|2.||Venous Thrombosis (Deep-Vein Thrombosis)
|3.||Disseminated Intravascular Coagulation
|5.||Factor X Deficiency
|1.||Souri, Masayoshi: 5 articles (11/2014 - 12/2010)|
|2.||Ichinose, Akitada: 5 articles (11/2014 - 12/2010)|
|3.||Ashley, C: 2 articles (01/2015 - 01/2015)|
|4.||Mangione, A: 2 articles (01/2015 - 01/2015)|
|5.||Nugent, D J: 2 articles (01/2015 - 01/2015)|
|6.||Naderi, M: 2 articles (01/2014 - 01/2013)|
|7.||Dorgalaleh, A: 2 articles (01/2014 - 01/2013)|
|8.||Levy, Jerrold H: 2 articles (05/2013 - 03/2008)|
|9.||Oldenburg, Johannes: 2 articles (05/2012 - 06/2010)|
|10.||Inbal, Aida: 2 articles (05/2012 - 03/2006)|
|1.||Factor XIII (Coagulation Factor XIII)IBA
05/31/2012 - "Recombinant factor XIII: a safe and novel treatment for congenital factor XIII deficiency."
05/01/2000 - "We analysed the early implantation tissues of normal women and of a patient with congenital factor XIII deficiency in order to study the role of maternal subunit A of factor XIII (XIIIA) in the development of extravillous cytotrophoblast. "
01/01/1996 - "Acquired factor XIII deficiency, however, is much more common, and preliminary studies suggest a lack of factor XIII to be an important feature of various diseases. "
12/10/1982 - "A randomized and controlled study was undertaken to test whether substitution with factor XIII concentrates influences the clinical course in patients with acute leukaemia and acquired factor XIII deficiency (less than or equal to 60%). "
01/01/2015 - "Pharmacokinetics and safety of plasma-derived factor XIII concentrate (human) in patients with congenital factor XIII deficiency."
01/01/2008 - "We report a novel mutation in factor XIIIA gene that caused severe congenital factor XIII deficiency in a 6 year and 8 month old male. "
01/01/2006 - "Today, more than 60 mutations in the factor XIIIA- and B-subunit genes are known leading to congenital factor XIII deficiency. "
12/01/2005 - "Factor XIII deficiency: new nonsense and deletion mutations in the human factor XIIIA gene."
12/25/2003 - "The 2 mutations of the factor XIIIA cause the instability, degradation, and rapid disappearance of FXIIIA in cytoplasm, thus resulting in hereditary factor XIII deficiency."
12/25/2003 - "To investigate the mechanisms of two novel missense mutations of factor XIIIA subunit gene (Arg77-->Cys,Ser413-->Trp) in the pathogenesis of hereditary factor XIII deficiency. "
01/01/1984 - "Finally, the wound healing problems of patients with severe factor XIII deficiencies may occur because of their inability to incorporate fibronectin into blood clots."
11/01/1986 - "Infusion of activated Factor XIII (20 units/rat) during a period of hyperfibronectinemia (908.0 +/- 55.1 micrograms/ml) resulted in a significant (p less than 0.05) decrease in plasma fibronectin (548.5 +/- 49.9 micrograms/ml) within 30 min. Thus Factor XIII deficiency in rats with bacteremia may contribute to the elevation in plasma fibronectin by altering kinetics associated with the clearance of fibronectin from the blood."
01/01/1988 - "Presumptive diagnosis of Factor XIII deficiency was made with a clot solubility screening test, and confirmation was accomplished by demonstrating the absence of cross-linked fibrin chains by electrophoresis. "
05/01/1980 - "Fibrin cross-linking in congenital factor XIII deficiency."
10/01/2013 - "Fibrin abnormalities (hypo/dysfibrinogenemia) and factor XIII deficiency are associated with infertility and pregnancy loss. "
12/29/1984 - "This latter finding suggests that, in addition to factor XIII deficiency, other causes are responsible for the high rate of fibrin crosslinking impairment in acute leukemia."
10/01/1999 - "Congenital factor XIII deficiency is a rare hemorrhagic syndrome with an altered fibrin stability, hemorrhagic diathesis and habitual abortions. "
01/01/1996 - "Half-life studies of factor XIII from plasma in comparison with factor XIII from placenta were done in rabbits by determination of the antigen and in patients with congenital factor XIII deficiency by determination of the activity and antigen. "
01/01/2014 - "Factor XIII deficiency was identified by an automated assay that measured factor XIII antigen. "
09/01/2011 - "Factor XIII antigen levels were 25% of predicted, and the diagnosis of factor XIII deficiency was made. "
08/01/2003 - "Extensive laboratory analyses revealed a factor XIII activity level of 17%, indicating factor XIII deficiency confirmed by a reduced XIIIA-antigen. "
12/31/1970 - "[Presence of a plasma antigen indispensable to the stabilization of fibrin in 2 cases on congenital factor XIII deficiency]."
06/01/2011 - "Successful long-term replacement therapy with FXIII concentrate (Fibrogammin(®) P) for severe congenital factor XIII deficiency: a prospective multicentre study."
01/01/2013 - " diagnosis of disease all patients with severe factor XIII deficiency(<1 U/dl) shouldreceive prophylactic substitution therapywith fresh frozen plasma (FFP) and cryoprecipitate as traditional choices or purified concentrateof blood coagulation factor XIII (Fibrogammin P) inorder to control severe and life-threatening clinical complications of factor XIII deficiency. "
01/01/1988 - "In light of the long half-life of this factor and the relatively low risk associated with new Factor XIII concentrates, such as Fibrogammin, prophylactic life-long replacement therapy should be considered for patients with severe Factor XIII deficiency."
06/01/1984 - "These results suggest that an increased affinity of noncrosslinked fibrin for plasmin(ogen) is contributory to the accelerated fibrinolysis observed in factor XIII deficiency, in addition to an absence of crosslinking of alpha 2-plasmin inhibitor to fibrin."
|7.||Messenger RNA (mRNA)IBA
02/01/2015 - "[Study on the molecular mechanisms of a novel large deletion of FXIIIA mRNA in a new hereditary factor XIII deficiency]."
03/01/1998 - "Thus, both mutations impaired normal processing of mRNA for the A subunit, resulting in his severe factor XIII deficiency."
03/01/1998 - "Novel deletion and insertion mutations cause splicing defects, leading to severe reduction in mRNA levels of the A subunit in severe factor XIII deficiency."
02/01/2015 - "To investigate the mechanisms of DelCD11-279 of factor XIII subunit A mRNA in the pathogenesis of hereditary factor XIII deficiency. "
01/01/2000 - "To understand the structure-function relationships of the factor XIII molecule and its clinical implications in factor XIII deficiency, we characterized its genetic defects and closely examined its gene products, including mRNA and protein levels. "
|8.||Platelet Membrane Glycoprotein IIbIBA
|10.||Fibrinogen (Factor I)FDA Link
11/01/2013 - "A clear association has only been established in women with fibrinogen and factor XIII deficiency. "
10/01/2014 - "Fibrinogen but not factor XIII deficiency is associated with bleeding after craniotomy."
02/01/2012 - "With the exception of fibrinogen and factor XIII deficiencies, it is currently unclear whether women with inherited bleeding disorders are at increased risk of miscarriage or antepartum haemorrhage. "
07/01/2012 - "Inherited coagulation defects were found in 27.2%; hemophilia A (70.6%), hemophilia B (13.9%), factor I deficiency (2.3%), factor V deficiency (1.6%), factor X deficiency (4.2%), factor VII deficiency (2.6%), factor XIII deficiency (1.1%), combined factor deficiency (2.1%) and unclassified coagulation disorders in 1.6% of studied patients. "
10/01/1975 - "Effects of fibrinogen concentration, Factor XIII deficiency, and Factor XIII inhibition."
|3.||Extracorporeal Membrane Oxygenation (ECMO)
|4.||Tooth Extraction (Tooth Extractions)