|1.||Renné, Thomas: 24 articles (09/2015 - 07/2005)|
|2.||Gailani, David: 12 articles (03/2014 - 07/2005)|
|3.||Kleinschnitz, Christoph: 9 articles (01/2014 - 03/2006)|
|4.||Nieswandt, Bernhard: 9 articles (02/2012 - 07/2005)|
|5.||Bork, Konrad: 7 articles (01/2015 - 05/2006)|
|6.||Stoll, Guido: 7 articles (02/2012 - 03/2006)|
|7.||Björkqvist, Jenny: 5 articles (08/2015 - 02/2011)|
|8.||Maas, Coen: 5 articles (08/2015 - 09/2008)|
|9.||Tucker, Erik I: 5 articles (03/2014 - 01/2009)|
|10.||McCarty, Owen J T: 5 articles (03/2014 - 01/2009)|
12/01/2015 - "Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding."
01/01/2014 - "we here report a case of ET accompanied with coagulation factor XII deficiency, which had clinically significant bleeding tendency. "
05/01/2012 - "In our case, a deficiency of factor XII was found, which is not associated with an increased bleeding risk. "
05/01/2012 - "Ten patients had decreased factor XII. Five patients had a suspected bleeding disorder which was confirmed in two of them. "
04/01/2011 - "Targeting polyphosphate-mediated factor XII activation offers the exciting possibility for a safe anticoagulation with minimal therapy-associated bleeding."
04/06/2010 - "Recent studies with factor XII-deficient mice revealed that the factor XII-induced intrinsic coagulation pathway is essential for pathological thrombus formation but dispensable for hemostasis. "
01/01/2015 - "Coagulation factor XII (fXII) is important for arterial thrombosis, but its physiological activation mechanisms are unclear. "
12/01/2014 - "Generation of active Factor XII (FXIIa) triggers blood clotting on artificial surfaces and may also enhance intravascular thrombosis. "
09/01/2014 - "Factor XII is also a key component in the fibrinolytic system and its deficiency is associated with increased thrombosis. "
08/01/2014 - "Factor XII regulates the pathological process of thrombus formation on ruptured plaques."
09/01/2012 - "Contact factor XII (FXII), an upstream activator of FXI, also contributes to experimental stroke, but is not required for hemostasis. "
02/01/2012 - "Blood coagulation factor XII--a neglected player in stroke pathophysiology."
09/01/2011 - "Further experimental work indicates that these pathways in conjunction with coagulation factor XII (FXII)-driven processes orchestrate a 'thrombo-inflammatory' cascade in acute stroke that results in infarct growth. "
02/15/2010 - "Intrinsic coagulation factor XII deficient (FXII(-/-)) mice are protected from ischemic stroke. "
02/15/2010 - "Enhanced cortical reperfusion protects coagulation factor XII-deficient mice from ischemic stroke as revealed by high-field MRI."
09/01/2008 - "Patient studies, genetically altered mouse models, and plasma assays analyzed functions of the factor XII-driven contact activation system for coagulation and inflammation. "
01/01/1993 - "Factor XII activation and inhibition in inflammation."
07/01/1978 - "A review of current knowledge of the biochemical mechanisms involved in the Hageman factor system is presented because of the potential role of these components in the development of inflammation."
04/01/2004 - "Thrombolytic therapy activates the contact system, and factor XII activation may activate the coagulation cascade and inflammation. "
09/01/2014 - "Factor XII: a drug target for safe interference with thrombosis and inflammation."
|5.||Habitual Abortion (Recurrent Miscarriage)
01/01/2000 - "The aim of this study was to assess the prevalence of factor XII (FXII) deficiency in women with a history of recurrent miscarriage. "
01/01/2014 - "Role of coagulation factor XII in unexplained recurrent abortions in the Greek population."
04/01/2008 - "A decrease in factor XII (FXII) activity has been observed in women with unexplained recurrent miscarriages. "
10/01/2005 - "The C46T polymorphism of the coagulation factor XII gene and idiopathic recurrent miscarriage."
09/01/2003 - "Ten of 67 women with primary recurrent abortion (14.9%) and 4 of 33 women (12.1%) with secondary recurrent abortion had reduced factor XII activity (<60%). "
|1.||Factor XI (Plasma Thromboplastin Antecedent)
|2.||Proteins (Proteins, Gene)
|3.||High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)
|5.||Aspirin (Acetylsalicylic Acid)
|6.||Complement C1s (C1 Esterase)
|4.||Renal Dialysis (Hemodialysis)