|1.||Marte, Filippo: 11 articles (12/2011 - 05/2009)|
|2.||Patanè, Salvatore: 11 articles (12/2011 - 05/2009)|
|3.||Peyvandi, Flora: 5 articles (10/2015 - 10/2002)|
|4.||Wojtukiewicz, Marek Z: 4 articles (05/2014 - 01/2012)|
|5.||Menegatti, Marzia: 3 articles (10/2015 - 06/2009)|
|6.||Yang, Likui: 3 articles (11/2014 - 07/2005)|
|7.||Rezaie, Alireza R: 3 articles (11/2014 - 07/2005)|
|8.||Kisiel, Walter: 3 articles (05/2014 - 04/2012)|
|9.||Ostrowska-Cichocka, Krystyna: 3 articles (05/2014 - 04/2012)|
|10.||Sierko, Ewa: 3 articles (05/2014 - 04/2012)|
09/01/1993 - "We suggest that the possibility of a spontaneous factor X recovery must be considered when evaluating efficacy of therapeutic agents in amyloidosis."
12/07/1992 - "Initially, factor X infusion studies showed a normal recovery, but when amyloidosis became overt the recovery decreased to 0%. "
06/01/1988 - "A reproducible model for the study of factor X kinetics in AA amyloidosis."
02/01/2014 - "Acquired factor X (FX) deficiency unrelated to amyloidosis is a rare disorder in which an anti-FX antibody is infrequently detected. "
03/01/2010 - "Systemic light-chain (AL) amyloidosis may be associated with acquired factor X (FX) deficiency and optimal management of this coagulopathy is unknown. "
|2.||Factor X Deficiency
01/01/2005 - "Genetic analysis of hereditary factor X deficiency in a French patient of Sri Lankan ancestry: in vitro expression study identified Gly366Ser substitution as the molecular basis of the dysfunctional factor X."
11/01/1988 - "Congenital factor X (Stuart-Prower factor) deficiency: a family study."
07/01/2015 - "Inherited Factor X (Stuart-Prower Factor) deficiency and its management."
01/01/2015 - "A novel factor X gene mutation Val (GTC) 384Ala (GCC) in a Chinese family resulting in congenital factor X deficiency."
11/01/2013 - "Femur fracture in a woman with severe factor X deficiency - an experience using factor X concentrate in surgery."
01/01/2016 - "The most frequent and severe bleeding complications occurred in patients with factor X levels below 10%. "
10/01/2015 - "Direct sequencing of the factor X gene (F10) identified two different mutations: the novel 33 bp in-frame deletion p.Thr176_Gln186, c.526_558del, which seems to be associated with milder bleeding symptoms and the c.785G>A, p.Gly262Asp missense mutation (previously reported as Gly222Asp), which is associated with severe bleeding symptoms. "
10/01/2015 - "Congenital factor X (FX) deficiency is a rare bleeding disorder inherited as an autosomal recessive trait with an incidence of 1 : 500 000-1 000 000. "
03/01/2015 - "Congenital factor X (FX) deficiency is a rare coagulation disorder of autosomal recessive inheritance, characterized by bleeding of variable severity. "
01/01/2014 - "The patient developed severe gastrointestinal bleeding as a result of a significant decrease of factor X activity. "
|4.||Venous Thrombosis (Deep-Vein Thrombosis)
04/01/2006 - "In conclusion, APTT-based assays, but not direct factor X activation-based assays, effectively detect the risk for venous thrombosis independent of FVL. "
06/01/2001 - "Factor X levels, polymorphisms in the promoter region of factor X, and the risk of venous thrombosis."
02/16/2007 - "This exosite is physiologically highly relevant for the recognition and inhibition of factor X/Xa by macromolecular substrates and provides a structural motif for the development of a new class of inhibitors for the treatment of deep vein thrombosis and angioplasty."
04/01/2006 - "One hundred ninety-seven subjects with a history of venous thrombosis and 211 controls were explored using 3 APCR assays, the original APTT-based assay (test A), an APTT-based assay with factor V depleted plasma pre-dilution (test B) and a direct factor X activation-based assay with the same pre-dilution (test C). "
05/01/2003 - "Factor X inhibitors are also being evaluated for use in the treatment of the acute coronary syndromes, pulmonary embolism and deep vein thrombosis. "
|5.||Disease Susceptibility (Diathesis)
10/01/1979 - "A case of severe haemorrhagic diathesis due to acquired deficiency of factor X (both immunologically and in procoagulant activity) is presented. "
12/01/2010 - "Factor X Umuahia: a severe bleeding diathesis associated with a novel mutation."
07/01/2004 - "The mutations in factor X, in this part of the world are most probably not the one, which would cause a severe bleeding diathesis."
01/01/2003 - "In utero transplantation of wild-type fetal liver cells rescues factor X-deficient mice from fatal neonatal bleeding diatheses."
12/01/1982 - "From these experiments, it is inferred that normal activation of factor X in plasma due to dilute thromboplastin requires factors VII, IX and VIII. An alternative extrinsic pathway that involves factors VII, IX, and VIII may be a major physiologic extrinsic pathway, and this pathway may help to explain the clinical observations of bleeding diatheses in patients deficient in factors IX or VIII."
|2.||Thromboplastin (Tissue Factor)
|3.||Fibrinogen (Factor I)
|4.||Factor Xa (Coagulation Factor Xa)
|5.||prothrombin complex concentrates (PPSB)
|6.||Amyloid (Amyloid Fibrils)
|9.||Prothrombin (Factor II)
|10.||Factor IX (PTC)
|1.||Drug Therapy (Chemotherapy)
|5.||Angioplasty (Angioplasty, Transluminal)