|1.||Rogers, Duncan F: 4 articles (09/2007 - 01/2005)|
|2.||Poole, P J: 4 articles (01/2006 - 01/2000)|
|3.||Black, P N: 4 articles (01/2006 - 01/2000)|
|4.||Rubin, Bruce K: 3 articles (07/2015 - 01/2006)|
|5.||Poole, Phillippa: 3 articles (01/2015 - 01/2010)|
|6.||Black, Peter N: 3 articles (01/2012 - 01/2003)|
|7.||Cates, Christopher J: 2 articles (01/2015 - 01/2012)|
|8.||Seok, Jeong Ho: 2 articles (03/2014 - 01/2014)|
|9.||Lee, Sang Kook: 2 articles (03/2014 - 01/2014)|
|10.||Park, Su Hyun: 2 articles (03/2014 - 01/2014)|
01/01/1997 - "Productive coughs are helped by expectorants. "
02/01/2010 - "There are no new studies showing that mucolytic agents are of value as monotherapies for chronic cough. "
08/01/2013 - "Expectorants can help patients who cough with marked sputum formation. "
05/01/2013 - "Role of mucolytics in wet cough."
01/01/2013 - "reduction of cough at day seven) from mucolytic agents, although differences were of little clinical relevance. "
|2.||Chronic Obstructive Pulmonary Disease (COPD)
01/01/2015 - "Mucolytics can improve disease outcome in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). "
01/01/2010 - "Even in patients with severe COPD who remain symptomatic despite maximal inhaled therapy the role of mucolytics remains unproven."
01/01/2010 - "Data that mucolytics improve symptoms, alter mucus or impact health-related quality of life in COPD patients receiving other standard therapy are unconvincing. "
01/01/2010 - "The review is based upon peer reviewed publications relating to the use of mucolytics in COPD cited in PubMed. "
01/01/2010 - "The evidence for the use of oral mucolytic agents in chronic obstructive pulmonary disease (COPD)."
01/01/1995 - "In a multicentre, comparative post-marketing surveillance study of more than 3000 patients with acute bronchitis, about half were treated with a herbal remedy (SinupretR) and the other half with various other expectorants. "
10/01/1954 - "[The treatment of chronically recurrent colds and bronchitis in children with percutaneous expectorants]."
11/01/2002 - "Our review did not identify any study of rigorous methodological quality that supported the efficacy or safety of mucolytics agents in infants for their in-label (isolated cough, acute bronchitis) and off-label (rhinopharyngitis) indications. "
05/01/2010 - "Patients with acute bronchitis, acute exacerbations of chronic bronchitis and asthmatic bronchitis suffer from cough with tenacious bronchial secretions requiring expectorants in addition to bronchodilating therapy. "
01/01/2008 - "The substantial antitussive effects of erdosteine were first documented in clinical trials even though mucolytic agents are regarded as not consistently effective in ameliorating cough in patients with bronchitis, although they may be of benefit to this population in other ways. "
|4.||Cystic Fibrosis (Mucoviscidosis)
04/01/1998 - "Modifications of bronchial secretions in cystic fibrosis patients account for the long-lasting use of mucolytic agents, despite the lack of adequately controlled clinical studies supporting this approach. "
03/01/2007 - "Mucolytics in cystic fibrosis."
01/01/2007 - "Actin limits enhancement of nanoparticle diffusion through cystic fibrosis sputum by mucolytics."
01/01/2006 - "Genetically engineered bacteria may be useful for delivery of mucolytics into cystic fibrosis lungs."
04/01/2003 - "aeruginosa (13 mucoïd and 7 non mucoïd) were selected from expectorants of cystic fibrosis children. "
|5.||Asthma (Bronchial Asthma)
08/01/2012 - "However, mucolytic agents have not been found effective in reversing the obstruction of acute asthma. "
05/31/1968 - "[Effect of mucolytic agents in the management ofbronchial asthma. "
04/20/1984 - "Do mucolytics help in chronic bronchitis and asthma?"
01/01/1983 - "Mucolytic agents induce bronchospasm and for the present should be contraindicated in asthma management. "
01/03/1977 - "[Selection of expectorants in the treatment of asthma and chronic bronchitis]."
|1.||Anti-Bacterial Agents (Antibiotics)
|4.||Adrenal Cortex Hormones (Corticosteroids)
|5.||Antitussive Agents (Antitussives)
|6.||Cholinergic Antagonists (Anticholinergics)
|7.||Codeine (Codeine Phosphate)
|8.||human DNASE1 protein (dornase alfa)
|9.||Bronchodilator Agents (Bronchodilators)
|10.||Nasal Decongestants (Decongestants)
|1.||Positive-Pressure Respiration (PEEP)
|2.||Drug Therapy (Chemotherapy)
|3.||Nutritional Support (Artificial Feeding)