|1.||Luszczki, Jarogniew J: 12 articles (12/2013 - 05/2003)|
|2.||Czuczwar, Stanislaw J: 8 articles (12/2011 - 05/2003)|
|3.||Borowicz, Kinga K: 7 articles (12/2015 - 08/2002)|
|4.||Czuczwar, Stanisław J: 7 articles (01/2012 - 08/2002)|
|5.||Patsalos, Philip N: 5 articles (02/2013 - 01/2005)|
|6.||Cnaan, Avital: 4 articles (10/2013 - 03/2010)|
|7.||Powell, Kim L: 3 articles (01/2015 - 02/2012)|
|8.||O'Brien, Terence J: 3 articles (01/2015 - 02/2012)|
|9.||Florek-Luszczki, Magdalena: 3 articles (12/2013 - 12/2011)|
|10.||Haratym-Maj, Agnieszka: 3 articles (12/2013 - 12/2011)|
09/01/2009 - "Observational studies of the efficacy of ethosuximide, a drug developed in the 1950s, reported complete seizure control in 40-60% of patients. "
05/05/2009 - "Ethosuximide eliminated the seizure frequency-dependent relationship and also significantly increased all indexes of the EPM test. "
10/01/2014 - "Therefore, the results of this study suggest that ethosuximide may compensate damage caused by seizure attacks and possibly other neuronal loss disorders."
10/01/1978 - "Acute dose--response studies were conducted to determine if ethosuximide had anticonvulsant activity against seizures evoked by stroboscopic stimulation of epileptic fowl and to correlate the observed effects with the concentration of the drug in the plasma. "
02/01/2015 - "Effects were greater when the anticonvulsant ethosuximide was injected 30 min prior to KA administration; ethosuximide allows forebrain seizure activity to be more easily examined in mice by suppressing seizures dominated by the brainstem. "
|2.||Absence Epilepsy (Absence Seizure)
12/01/1996 - "Ethosuximide is effective against absence seizures. "
05/01/2014 - "Due to reduced side effects, ethosuximide remains the first line treatment for childhood absence epilepsy."
10/30/2007 - "Mice heterozygous for the mutation demonstrated behavioral arrest associated with 6-to 7-Hz spike-and-wave discharges, which are blocked by ethosuximide, a first-line treatment for absence epilepsy in man. "
07/01/2012 - "Ethosuximide is a minor antiepileptic drug, available in France since 1965, indicated in the epilepsy absence, whose interest was reassessed from recent clinical trials, showing that it was the first choice, in term of risk benefit relationship, in this indication. "
10/01/2015 - "T-type (Ca(V)3) channels are a target of ethosuximide, widely used in absence epilepsy. "
03/01/1973 - "Improved control of epilepsy by monitoring plasma ethosuximide."
11/20/2015 - "Ethosuximide (ETH), an anticonvulsant drug is used for the treatment of epileptic seizures. "
10/01/2008 - "Ethosuximide is a medication used to treat seizure disorders in humans, and we previously demonstrated that ethosuximide can delay age-related changes and extend the lifespan of the nematode Caenorhabditis elegans. "
01/01/2007 - "In the treatment of epilepsy, ethosuximide has a narrow therapeutic profile. "
06/01/1999 - "Plasma ethosuximide levels ranged from 55 to 89 micrograms/mL. The clinical response was not influenced by the patients' preexisting treatment or by the etiology of the epilepsy. "
|4.||Partial Epilepsies (Epilepsy, Partial)
02/01/1994 - "It is suggested that ethosuximide might be effective in the control of probable partial seizure disorders. "
06/01/1999 - "Ethosuximide is effective in the treatment of epileptic negative myoclonus in childhood partial epilepsy."
06/01/1999 - "The aim of our study was to evaluate the effectiveness of ethosuximide in the treatment of epileptic negative myoclonus, a motor disorder that can occur in childhood partial epilepsy. "
01/01/2005 - "To clarify the neurophysiological mechanism of epileptic negative myoclonus (NM) of a patient with atypical benign partial epilepsy whose NM was completely suppressed with ethosuximide. "
06/01/1999 - "We introduced ethosuximide in nine patients with partial epilepsy of varying etiology (idiopathic, cryptogenic, symptomatic) who presented with epileptic negative myoclonus. "
|5.||Neurodegenerative Diseases (Neurodegenerative Disease)
|1.||Valproic Acid (Valproate, Semisodium)
|5.||Anticonvulsants (Antiepileptic Drugs)
|1.||Drug Therapy (Chemotherapy)