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Ethacrynic Acid (Etacrynic Acid)

A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
Also Known As:
Etacrynic Acid; Edecrin; Ethacrinic Acid; Ethacrynate Sodium; Ethacrynic Acid, Sodium Salt; Hydromedin; Acid, Etacrynic; Acid, Ethacrinic; Acid, Ethacrynic; Sodium, Ethacrynate; Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-
Networked: 272 relevant articles (13 outcomes, 30 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Schmidt-Wolf, Ingo G H: 4 articles (10/2014 - 01/2009)
2. Yuan, Fan: 4 articles (10/2012 - 08/2004)
3. Czuczwar, Stanisław J: 3 articles (01/2013 - 12/2009)
4. Łukawski, Krzysztof: 3 articles (01/2013 - 12/2009)
5. Zhao, Guisen: 3 articles (12/2012 - 08/2007)
6. Wang, Rui: 3 articles (12/2012 - 08/2007)
7. Jing, Yongkui: 3 articles (12/2012 - 08/2007)
8. Roarke, Michael C: 2 articles (12/2015 - 07/2010)
9. Nguyen, Ba D: 2 articles (12/2015 - 07/2010)
10. Miller, Jamie L: 2 articles (08/2014 - 01/2014)

Related Diseases

1. Glaucoma
2. Heart Failure
3. Alkalosis
4. Ascites
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Diuretics
2. Cisplatin (Platino)
3. Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)
4. Indomethacin (Indometacin)
5. Cysteine (L-Cysteine)
6. Acetylcysteine (Siran)
7. NF-kappa B (NF-kB)
8. Aurintricarboxylic Acid
9. Aldehydes
10. meralluride

Related Therapies and Procedures

1. Sutures (Suture)
2. Microelectrodes
3. Lasers (Laser)
4. Intravenous Injections
5. Ischemic Postconditioning