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Estradiol (Estrace)

Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.
Also Known As:
Estrace; Oestradiol; 17 beta-Oestradiol; Aerodiol; Estraderm TTS; Estradiol Hemihydrate; Estradiol Hemihydrate, (17 alpha)-Isomer; Estradiol Monohydrate; Estradiol, (+-)-Isomer; Estradiol, (-)-Isomer; Estradiol, (16 alpha,17 alpha)-Isomer; Estradiol, (16 alpha,17 beta)-Isomer; Estradiol, (17-alpha)-Isomer; Estradiol, (8 alpha,17 beta)-(+-)-Isomer; Estradiol, (8 alpha,17 beta)-Isomer; Estradiol, (9 beta,17 alpha)-Isomer; Estradiol, (9 beta,17 beta)-Isomer; Estradiol, Monosodium Salt; Estradiol, Sodium Salt; Estradiol-17 alpha; Estradiol-17beta; Novartis Pharmaceuticals Brand of Estradiol; Orion Brand of Estradiol; Ovocyclin; Vivelle; 17 beta Estradiol; 17 beta Oestradiol; Estradiol 17 alpha; Estradiol 17 beta; Estradiol 17beta; Estradiol Orion Brand; 17 beta-Estradiol; Estradiol-17 beta; Estra-1,3,5(10)-triene-3,17-diol (17beta)-
Networked: 10364 relevant articles (363 outcomes, 1195 trials/studies)

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Drug Context: Research Results

Experts

1. Stanczyk, Frank Z: 27 articles (10/2015 - 01/2003)
2. Hankinson, Susan E: 25 articles (10/2014 - 11/2002)
3. Dowsett, Mitch: 24 articles (02/2016 - 01/2005)
4. Mueck, A O: 24 articles (06/2012 - 07/2000)
5. Seeger, H: 23 articles (06/2012 - 07/2000)
6. Ylikorkala, Olavi: 20 articles (10/2015 - 01/2004)
7. Etgen, Anne M: 20 articles (09/2013 - 09/2003)
8. Santen, Richard J: 19 articles (07/2015 - 02/2002)
9. Suzuki, Takashi: 18 articles (01/2015 - 05/2003)
10. Sasano, Hironobu: 18 articles (05/2013 - 05/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Hemorrhage
4. Ischemia
5. Osteoporosis

Related Drugs and Biologics

1. Estrogens (Estrogen)
2. Progesterone
3. Testosterone (Sustanon)
4. Hormones
5. Tamoxifen
6. Estrone (Folliculin)
7. Prolactin
8. Insulin (Novolin)
9. Cyproterone Acetate
10. Follicle Stimulating Hormone (Follitropin)

Related Therapies and Procedures

1. Hormone Replacement Therapy (Therapy, Hormone Replacement)
2. Female Contraceptive Devices (Vaginal Ring)
3. Ovariectomy (Oophorectomy)
4. Estrogen Replacement Therapy
5. Drug Therapy (Chemotherapy)