Esophageal Perforation

05/01/2021 - "In acute intrathoracic esophageal perforation cases, high index of suspicion, multidisciplinary team expertise, antibiotics and hybrid treatment strategies, have significantly improved outcomes of patients in recent years. "
01/01/2019 - "Nutrition, thyroid repletion, and culture-directed IV antibiotics are necessary to optimize esophageal perforation repair."
12/01/2003 - "Although esophageal perforations are generally managed surgically, conservative management of localized perforations has become more common especially with improved antibiotics and the use of nonsurgical interventional drainage techniques. "
07/01/1986 - "A study of 90 cases of esophageal perforation in the antibiotic era emphasizes individualized treatment and options of therapy based on a fundamental understanding of modifying pathophysiologic factors. "
01/01/2016 - "In this largest reported sample of neonates treated for esophageal perforation, nonoperative management with bowel rest, parenteral nutrition, and antibiotics was successful."

01/01/2012 - "We report a case of barotraumatic esophageal perforation caused by the explosion of a carbonated beverage containing plastic bottle into the mouth. "
06/01/2010 - "The use of a self-expandable plastic stent for an iatrogenic esophageal perforation."
03/01/2001 - "Successful treatment of esophageal perforation with a removable self-expanding plastic stent."
12/01/2008 - "We sought to determine the efficacy of a self-expanding plastic stent for esophageal perforation before neoadjuvant chemoradiation in a single patient. "
09/01/2008 - "Meta-analysis of randomized, controlled trials showed that metallic stents were associated with significantly reduced stent-related mortality (1.7% vs. 11.1% for the plastic group, odds ratio (OR), 0.2; 95% confidence interval (CI), 0.06-0.74; P = 0.02), morbidity in the form of reduced esophageal perforation (1.4% vs. 9.4% for plastic stent, OR, 0.27; 95% CI, 0.08-0.89; P = 0.03), and stent migration, yet increased rate of tumor in-growth (13% vs. 1.6% for plastic stents, OR, 4.84; 95% CI, 0.99-23.76; P = 0.05). "

11/01/2007 - "The aim of this study was to investigate the efficacy of the fibrin tissue patch and to analyze its use in patients with esophageal perforation. "
11/01/2007 - "Surgical primary repair with fibrin tissue patch is the most successful treatment option in the management of esophageal perforation."
11/01/2007 - "The sealing effect of a fibrin tissue patch on the esophageal perforation area in primary repair."
01/01/2000 - "Esophageal perforations up to 20 cm aboral and a maximum diameter of 1.5 cm could be treated by rigid endoscopical fibrin gluing. "
01/01/2000 - "This case demonstrates the successful endoscopic treatment of an esophageal perforation with mediastinal empyema by fibrin gluing. "

12/01/2019 - "However, perioperative and delayed esophageal perforations were caused by chronic irritation because of metal failure. "
12/01/2019 - "In the delayed group (N=3), chronic irritation caused by metal failure was the main cause of esophageal perforation. "
06/01/2013 - "[Successful treatment of a wide iatrogenic esophageal perforation after late implentation of double covered metal prothesis]."
04/01/2009 - "Esophageal perforation from a metal screw and plate."
01/01/2018 - "Self-expanding metal stent (SEMS) is effective and safe for the treatment of benign esophageal perforations or leaks. "

01/01/2013 - "This case report suggests that effective drainage and the use of fibrin glue sealant may be one of the treatment options for esophageal perforation. "
02/01/2000 - "[Esophageal perforation and postoperative fistulae of the upper digestive tract treated endoscopically with the application of Tissucol]."
05/01/1996 - "Beneficial effects of fibrin glue on esophageal perforation."
02/01/2000 - "We consider that the endoscopic application of fibrin glue should become the first step in the conservative treatment of small esophageal perforations or postoperative esophageal pleural fistulae, especially in cases of high output fistulae. "
01/01/2013 - "Esophageal perforation caused by a fish bone treated with surgically indwelling drainage and fibrin glue injection for fistula formation."

07/28/2018 - "Stent migration, which causes issues in stent therapy for esophageal perforations, can counteract the therapeutic effects and lead to complications. "
05/01/1983 - "It is basically a consecutive, multimodal integration of selective concentration of therapeutic effects (extensive radiotherapy, topical application of bleomycin polyacrylate pasta, lymphatic chasing with colloidal bleomycin, and spatial concentration of cisplatin as the result of radiation-induced inflammation), perpetuation of the repairable DNA damage, and biological amplifications (protection against esophageal perforation with polyacrylate coating, and specific cancer cell recruitment). "

12/01/2019 - "A 73-year-old patient had esophageal perforation on the fourth day of the first docetaxel, cisplatin, 5-fluorouracil cycle. "
12/01/2019 - "Here, we report the case of a successfully treated patient with thoracic esophageal cancer who had esophageal perforation during docetaxel, cisplatin, and 5-fluorouracil chemotherapy. "
05/01/1983 - "It is basically a consecutive, multimodal integration of selective concentration of therapeutic effects (extensive radiotherapy, topical application of bleomycin polyacrylate pasta, lymphatic chasing with colloidal bleomycin, and spatial concentration of cisplatin as the result of radiation-induced inflammation), perpetuation of the repairable DNA damage, and biological amplifications (protection against esophageal perforation with polyacrylate coating, and specific cancer cell recruitment). "

02/01/2019 - "Our experience suggests that the use of PGA sheets with fibrin glue is a feasible, safe, and effective way of treating large esophageal perforations during ESD."

10/01/1977 - "Since proteolytic enzyme digestion of bolus impaction carries a clear risk of fatal esophageal perforation, early therapeutic administration of glucagon during initial esophagography affords a safe and effective acute-care radiologic adjunct. "

10/01/1977 - "Since proteolytic enzyme digestion of bolus impaction carries a clear risk of fatal esophageal perforation, early therapeutic administration of glucagon during initial esophagography affords a safe and effective acute-care radiologic adjunct. "

07/01/2009 - "Endoluminal esophageal stent placement is an effective treatment of most spontaneous esophageal perforations. "
01/01/2017 - "Covered stents appear to be beneficial in closing esophageal perforations in children and can avoid the high morbidity of a surgical repair. "
08/01/2014 - "The stents appear to be safe and beneficial in closing esophageal perforations, especially post-dilation. "
10/01/2008 - "We report a case of esophageal perforation with a wooden fence post treated successfully with a covered esophageal stent."
10/01/2002 - "A self-expanding coated stent was eventually placed to seal the esophageal perforation with significant improvement in the clinical condition of the patient. "

05/01/2023 - "Endoscopic stenting and endoscopic vacuum therapy are the 2 therapies most widely described across a diverse patient population and appear to be safe and effective when treating esophageal perforation, in the proper clinical setting. "
08/20/2018 - "Utilized as either a primary or rescue therapy, EVAC therapy appears to be beneficial in the management of esophageal perforations or leaks."
10/01/2023 - "Endoscopic vacuum therapy for esophageal perforations: is it risk effective for every size of defect?"
01/01/2023 - "BACKGROUND : Endoscopic vacuum therapy (EVT) is a novel treatment for esophageal perforations. "
08/20/2018 - "To investigate the efficacy of primary and rescue endoluminal vacuum (EVAC) therapy in the treatment of esophageal perforations and leaks. "

12/01/2021 - "The first-line treatment in most cases is the conservative treatment (dilatation with a Savary bougie or balloon), but in some CES types, dilatation may be ineffective or result in esophageal perforation with serious complications or lethal outcome. "
07/01/2018 - "we report a case of cervical esophageal perforation that was effectively treated by a conservative management with acrylic glue injection. "
04/01/2013 - "Efficacy of surgical versus conservative treatment in esophageal perforation: a systematic review of case series studies."
11/01/2010 - "The purpose of this study is to report our management and add to the growing evidence for conservative management of esophageal perforation in children. "
10/01/2000 - "The aim of this study was to analyse the outcome of patients with esophageal perforations given surgical and conservative treatment. "

01/01/2017 - "Although traditional open techniques are the accepted gold standard of treatment for esophageal perforation, minimally invasive esophagectomy plays an important role in experienced hands and may be offered to such patients."
09/01/2015 - "Emergent esophagectomy represents a safe option for the treatment of esophageal perforation, with mortality comparable to elective esophagectomy."
11/01/2010 - "We undertook this study to report on primary esophagectomy and reconstruction in esophageal perforations with expert surgeons and selected patients. "
08/01/2022 - "Urgent endoscopy was conducted in eight cases, of which three were worse after endoscopy, and in one case, total esophagectomy was conducted due to subsequent esophageal perforation. "
07/01/2022 - "While patients diagnosed early can be managed by primary closure of esophageal perforation, those presenting beyond 24 hours often require an esophagectomy with salivary diversion and feeding access with a plan for the reconstruction of the alimentary tract at a later date. "

12/01/2007 - "The creation of a symmetric and floppy wrap during Nissen fundoplication can be facilitated greatly by intraoperative endoscopy and may lead to improved clinical outcomes without the risk of esophageal perforation."
01/01/1996 - "The purpose of this study was to determine possible mechanisms of 17 gastric and esophageal perforations that occurred during laparoscopic Nissen fundoplication. "
07/01/2019 - "The patient with esophageal perforation submitted to mesh removal, drainage, and an anterior partial fundoplication. "
12/01/2005 - "The overall complication rate for laparoscopic fundoplication was 7.7% (5.7% surgical and 2% nonsurgical complications), including rates of 0.6% for esophageal perforations and 0.6% for splenic lesions. "
04/01/2002 - "Fundoplication was used in 8 patients as part of hiatus reconstruction (n = 6) or repair of esophageal perforation (n = 2). "