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Esophageal Achalasia (Megaesophagus)

A motility disorder of the ESOPHAGUS in which the LOWER ESOPHAGEAL SPHINCTER (near the CARDIA) fails to relax resulting in functional obstruction of the esophagus, and DYSPHAGIA. Achalasia is characterized by a grossly contorted and dilated esophagus (megaesophagus).
Also Known As:
Megaesophagus; Cardiospasm; Achalasia; Achalasias; Achalasias, Esophageal; Cardiospasms; Esophageal Achalasias; Achalasia, Esophageal
Networked: 1407 relevant articles (137 outcomes, 168 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Deglutition Disorders (Dysphagia)
2. Gastroesophageal Reflux (GERD)
3. Spasm (Spasms)
4. Diffuse Esophageal Spasm (Esophageal Spasm)
5. Heartburn (Pyrosis)

Experts

1. Huebner, Angela: 19 articles (09/2015 - 02/2003)
2. Koehler, Katrin: 12 articles (09/2015 - 03/2006)
3. Patti, Marco G: 12 articles (07/2015 - 05/2003)
4. Zaninotto, Giovanni: 9 articles (06/2015 - 01/2004)
5. Huebner, A: 9 articles (08/2010 - 11/2000)
6. Kashiwagi, Hideyuki: 8 articles (10/2015 - 01/2006)
7. Omura, Nobuo: 8 articles (10/2015 - 01/2006)
8. Yano, Fumiaki: 7 articles (10/2015 - 01/2006)
9. Tsuboi, Kazuto: 7 articles (10/2015 - 01/2006)
10. Yanaga, Katsuhiko: 7 articles (10/2015 - 01/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Esophageal Achalasia:
1. Botulinum Toxins (Botulinum Toxin)IBA
2. onabotulinumtoxinA (Botox)FDA Link
3. Nifedipine (Adalat)FDA LinkGeneric
4. BariumIBA
5. CosmeticsIBA
6. Colloids (Colloid)IBA
7. AntibodiesIBA
8. Nitric Oxide (Nitrogen Monoxide)FDA Link
9. Calcium Channel Blockers (Blockers, Calcium Channel)IBA
10. CalciumIBA

Therapies and Procedures

1. Fundoplication
2. Balloon Dilation
3. Injections
4. Stents
5. Esophagectomy