Ergolines

01/01/1985 - "Both ergolines and ergopeptines are used in treatment of Parkinson's disease and their therapeutic efficacy, as well as their propensity to develop undesirable side effects is under investigation. "
04/01/2011 - "Observational studies addressing the frequency of moderate or severe valvular regurgitation among ergoline-treated patients with Parkinson's disease were considered for a meta-analysis. "
08/01/2006 - "Ergoline and non-ergoline derivatives in the treatment of Parkinson's disease."
01/01/2001 - "The tetracyclic ergoline derivative cabergoline was investigated in three studies to test its efficacy in treating the motor symptoms of Parkinson's disease. "
05/01/2014 - "Non-ergoline dopamine agonists (DA) are effective treatments for Parkinson's disease (PD). "

11/01/1983 - "Correlation between inhibitory effect on prolactin secretion and antitumor activity of new ergoline compounds on DMBA-induced tumors in rats."
01/01/1979 - "Nitrosourea derivatives of ergolines have been synthesized for the purpose of obtaining agents with both prolactin-and tumor-inhibitory activity. "
01/01/1977 - "Ergolines as potential prolactin and mammary tumor inhibitors."
09/01/1984 - "The effect of the new, prolactin-lowering ergoline derivative FCE21336 and medroxyprogesterone acetate (MPA) given alone and in combination was tested on DMBA-induced mammary tumors in rats. "
03/01/1976 - "Alteration of growth of dimethylbenz[a]anthracene-induced mammary tumors was caused by removal of estrogen (ovariectomy), or insulin (diabetes), or by inhibition of prolactin secretin (treatment with an ergoline derivative). "

08/01/2014 - "It displays favorable pharmacokinetic and in vitro safety profiles, and served as a lead compound in a program to explore ergoline derivatives as potential drug candidates for the treatment of narcolepsy. "
08/01/2014 - "Ergoline-derived inverse agonists of the human h3 receptor for the treatment of narcolepsy."
02/01/2015 - "From ergolines to indoles: improved inhibitors of the human H3 receptor for the treatment of narcolepsy."

02/01/1986 - "The ergoline derivative, Metergoline, in a dosage of 4 to 24 mg/day, was administered for one to eight months to 42 patients with hyperprolactinemic amenorrhea. "
08/01/1981 - "Pergolide, a synthetic ergoline, is a potent long-acting dopaminergic drug effective in Parkinson's disease and amenorrhea-galactorrhea. "

08/01/1981 - "Pergolide, a synthetic ergoline, is a potent long-acting dopaminergic drug effective in Parkinson's disease and amenorrhea-galactorrhea. "