|3.||Hereditary Hemorrhagic Telangiectasia
|1.||Davidson, Terence M: 8 articles (11/2013 - 03/2007)|
|2.||Holzmann, David: 6 articles (01/2015 - 08/2006)|
|3.||Zarrabeitia, Roberto: 6 articles (07/2012 - 06/2004)|
|4.||Lacombe, Pascal: 5 articles (01/2015 - 03/2012)|
|5.||Dupuis-Girod, Sophie: 5 articles (01/2015 - 04/2010)|
|6.||Olivieri, Carla: 4 articles (11/2015 - 07/2006)|
|7.||Pagella, Fabio: 4 articles (11/2015 - 07/2006)|
|8.||Danesino, Cesare: 4 articles (11/2015 - 07/2006)|
|9.||Paintaud, Gilles: 4 articles (01/2015 - 02/2012)|
|10.||Decullier, Evelyne: 4 articles (01/2015 - 02/2012)|
05/01/2012 - "Recent reports have demonstrated marked improvement of epistaxis with administration of either intravenous or topical bevacizumab. "
03/01/2012 - "Intranasal submucosal bevacizumab effectively treats HHT-associated epistaxis for up to 12 months following treatment."
05/01/2014 - "Secondary objectives were to study the bioavailability and efficacy of bevacizumab against epistaxis when given as a nasal spray. "
01/01/2015 - "The relationship between its serum concentration and change in both CI and epistaxis duration was investigated to design the bevacizumab maintenance dosing regimen of future therapeutic studies. "
07/01/2014 - "This study investigates whether drastically lower dosages of bevacizumab than normally used in oncological treatment could control epistaxis in patients with HHT and medically refractory epistaxis. "
08/01/2006 - "Bilateral epistaxis in children: efficacy of bilateral septal cauterization with silver nitrate."
06/01/2012 - "Nasal antiseptic ointment and silver nitrate cauterization were found to have similar outcomes in the treatment of recurrent epistaxis."
01/01/2012 - "The group treated with 75% silver nitrate had 88% complete resolution of epistaxis compared to 65% in the group treated with 95% silver nitrate (P = 0.01). "
01/01/2011 - "We would recommend the use of 75% silver nitrate cauterization in the management of childhood epistaxis, it appears to be more efficacious, has fewer side effects and is better tolerated."
01/01/2011 - " to evaluate which concentration of silver nitrate cauterization was more efficacious in the management of idiopathic childhood epistaxis. "
|3.||polyvinyl alcohol formaldehyde foamIBA
01/01/1989 - "Merocel intra-nasal pack are very effective in controlling epistaxis. "
08/01/2005 - "RapidRhino and Merocel are equally effective in the control of anterior epistaxis but RapidRhino is significantly more comfortable for the patient and easier for the healthcare worker during insertion and removal."
06/01/1996 - "Merocel nasal packing is an effective form of first line treatment in patients with epistaxis."
08/01/1995 - "It was concluded that Merocel nasal tampons should be considered effective in the first line treatment of severe epistaxis uncontrolled by simple measures. "
08/01/2005 - "A prospective non-blinded randomized controlled trial to compare the efficacy of Merocel and RapidRhino nasal packs in the treatment of anterior epistaxis. "
|4.||Tranexamic Acid (AMCA)FDA Link
12/01/2015 - "A short-cut review was carried out to establish whether intravenous tranexamic acid is beneficial in managing acute epistaxis. "
02/01/1988 - "This study evaluated oral tranexamic acid as an adjunct in controlling epistaxis and preventing or reducing recurrent epistaxis. "
12/01/2015 - "It is concluded that there is no evidence to support or refute the use of intravenous tranexamic acid in acute epistaxis and that local advice should be followed. "
12/01/2015 - "BET 1: Intravenous tranexamic acid in the treatment of acute epistaxis."
09/01/2014 - "Positive effects of tranexamic acid, an antifibrinolytic drug, have been reported on epistaxis related to this disorder. "
|5.||ankaferd blood stopperIBA
10/01/2011 - "The aim of this study was to assess the hemostatic efficacy of Ankaferd Blood Stopper (ABS) in an experimental epistaxis model and to determine the histopathologic alterations with topical ABS application. "
11/01/2011 - "Persistent nasal bleeding due to nasal CPAP application in 2 premature newborns successfully treated with topical "Ankaferd blood stopper"."
09/01/2010 - "Prospective, randomized, controlled clinical trial of Ankaferd Blood Stopper in patients with acute anterior epistaxis."
09/01/2010 - "This is a study evaluating the efficacy of Ankaferd Blood Stopper (ABS) as a hemostatic agent compared to hemostasis by phenylephrine in patients with anterior epistaxis. "
11/01/2011 - "The efficacy of Ankaferd Blood Stopper in heparin-induced hemostatic abnormality in a rat epistaxis model."
|6.||Lidocaine (Xylocaine)FDA LinkGeneric
05/01/2008 - "Compared with the CTNA method, in which the taste of lidocaine gel was more acceptable, EGNA appeared to be more tolerable, caused less epistaxis, improved visualization capacity, and reduced procedure time."
01/01/2005 - "Nebulized lidocaine before nasogastric tube insertion reduced patient discomfort but increased risk for nasal bleeding."
01/01/2005 - "Nebulised lidocaine before nasogastric tube insertion reduced patient discomfort but increased risk of nasal bleeding."
08/01/2004 - "Epistaxis occurred more frequently in the lidocaine group (17% versus 0%; difference 17%; 95% CI 3.5% to 31%). "
10/01/2011 - "Topical ABS, gelatin foam (GF), adrenalin + lidocaine (AL), and serum physiologic as negative control (C) were applied to the animals for controlling epistaxis. "
11/01/2000 - "Superselective embolisation with gelatin sponge is an effective and safe treatment technique for intractable idiopathic epistaxis."
11/01/2000 - "The embolic material was gelatin sponge in 27 procedures, microcoils in 9 and both gelatin sponge and microcoils in 4. Immediate cessation of nasal bleeding was obtained in all patients after embolisation. "
08/01/2010 - "The novel gelatin sponge appears to be a promising hemostatic matrix, which could be of great benefit for patients suffering from epistaxis and other acute injuries resulting in severe bleeding."
01/01/2014 - "This pilot study demonstrated that gelatin-thrombin matrix is a safe and both a clinically effective and cost-saving means of treating posterior epistaxis. "
01/01/2014 - "To evaluate the effectiveness of gelatin-thrombin matrix for first line treatment of posterior epistaxis. "
|8.||Betamethasone (Celestone)FDA Link
01/01/2015 - "Betamethasone was effective in reducing the size of polyps, but was associated with increased reports of mild side effects, nasal bleeding and discomfort.Risk"
01/01/2013 - "Betamethasone was effective in reducing the size of polyps, but was associated with increased reports of mild side effects, nasal bleeding and discomfort.Risk"
01/01/2011 - "Betamethasone was effective in reducing the size of polyps, but was associated with increased reports of mild side effects, nasal bleeding and discomfort.Risk"
06/01/2011 - "Tamoxifen appears to be an effective agent for the treatment of epistaxis due to HHT."
02/01/2009 - "Tamoxifen appears to be an effective agent for the treatment of epistaxis due to HHT."
06/01/2011 - "The aim of this study was to examine the efficacy of an anti-estrogenic agent, tamoxifen, in the treatment of HHT-associated epistaxis. "
02/01/2009 - "The aim of this study was to examine the efficacy of an antiestrogenic agent, Tamoxifen, in the treatment of HHT-associated epistaxis. "
02/01/2009 - "Of the 21 participants who completed the trial, alleviation of the epistaxis was noted in 9 of 10 tamoxifen-treated patients and 3 of 11 placebo-treated patients (including 2 with only temporary improvement). "
|10.||Cocaine (Cocaine HCl)IBA
03/01/2014 - "The aim of this study was to compare the efficacy of 4% and 6% topical cocaine solutions in reducing epistaxis during NTI. "
03/01/2014 - "The spraying of either 4% or 6% topical cocaine into the nasal cavity gives comparable effects for intubation-related epistaxis. "
03/01/2014 - "The incidence of epistaxis was 43.59% (17/39) in the 4% cocaine group and 50% (20/40) in the 6% cocaine group (p = 0.57). "
05/01/2000 - "There were no cases of postoperative epistaxis requiring nasal packing or hospital admission in the oxy/lido group, whereas one patient in the cocaine group developed epistaxis 8 days after surgery, which required treatment. "
11/01/2008 - "Two cocaine users presented with mid-facial pain, epistaxis, and systemic symptoms. "
01/01/2009 - "Being familiar with the pathway and branch patterns of the internal maxillary artery in pterygopalatine fossa is important for treating the uncontrol epistaxis and endoscopic pterygopalatine fossa surgery, the rules described by A, B, C, D in our experiments will be helpful in ligation of internal maxillary artery during the endoscopic transnasal/maxillary-pterygopalatine fossa surgery."
10/01/2007 - "Transcatheter external carotid arterial embolization is a simple, safe and effective treatment for the intractable epistaxis, which has more advantages than external carotid artery ligation, and comprehensive methods can effectively and thoroughly cure intractable epistaxis."
06/01/2007 - "A major advance in the management of posterior epistaxis has been the development of the technique of endoscopic ligation. "
08/01/1989 - "Internal maxillary artery ligation is effective in treating epistaxis. "
06/01/1984 - "Intraoral ligation of the maxillary artery for intractable posterior epistaxis has been used effectively in 14 consecutive patients, all of whom had failed conventional anterior and posterior packing techniques. "
08/01/2001 - "One other patient had a further minor epistaxis 2 days following embolization, which was treated successfully with cautery. "
10/01/2008 - "To determine the long-term outcome for children treated for recurrent epistaxis, and to compare the efficacy of antiseptic cream treatment and nasal cautery. "
05/01/2011 - "We present a study of our unit's management of epistaxis, comparing 48 h of nasal packing with nasendoscopic-guided cautery. "
04/01/2009 - "Twenty patients with severe intractable posterior epistaxis, who had underwent various procedures like nasal packing, electro- or chemical cautery or others and still exacerbated, were subjected to this study. "
06/01/2006 - "This study sought to determine if bipolar cautery can be effectively and safely used in treating HHT-associated epistaxis. "
10/01/2005 - "Although no curative treatment for HHT exists, Nd:YAG laser treatment seems to constitute a simple and efficient method of epistaxis control, resulting in a significant improvement in quality of life."
10/01/2005 - "Recurrence of epistaxis after Nd:YAG laser application and measurement of HR-QoL using the International Quality of Life Assessment questionnaire, version 1.1 (IQOLA 1.1), was found. "
10/01/2005 - "Twenty-seven consecutive patients with HHT and mild to moderate degrees of epistaxis were followed-up for 2 years after Nd:YAG laser treatments. "
06/28/2001 - "The therapeutic effects of epistaxis by radiofrequency and ND:YAG laser are similar, but radiofrequency is simpleier, easy to perform, more and useful than Nd:YAG laser."
06/28/2001 - "Three hundred and ten patients with epistaxis were treated with radiofrequency and Nd:YAG laser, respectively. "
07/01/2015 - "The most effective and safe treatment for intractable deep-seated epistaxis is electrocoagulation under nasal endoscopy."
06/01/2013 - "The SPA electrocoagulation technique seems to be safe, simple, fast, and effective with low rates of morbidity and complications for the management of refractory posterior epistaxis. "
06/01/2006 - "Bipolar electrocautery is a safe and effective tool for the intraoperative control of HHT-related epistaxis. "
11/01/2002 - "Transnasal sphenopalatine artery electrocautery is a simple, effective and safe method for the treatment of posterior epistaxis."
12/01/2013 - "The use of bipolar electrocautery in adult epistaxis management: using audit of one hundred and twenty-four cases to define a standardised protocol."
11/01/2013 - "Independent variables included sex, age, epistaxis severity score, surgical techniques (including laser), and blood pressure parameters (baseline, preinduction, and postintubation). "
10/01/2013 - "A 10-year-old KWPN (Royal Warmblood Studbook of the Netherlands) gelding was euthanized after developing severe neurological symptoms preceded by severe epistaxis during laser treatment for progressive ethmoid haematoma (PEH) in the right nasal cavity. "
12/01/2011 - "Laser treatment reduces epistaxis in HHT patients with mild to moderate epistaxis for at least 6 months; this group of patients have reduced quality of life compared to the background population."
12/01/2011 - "This prospective study measures the objective effect of laser treatment in HHT patients with mild to moderate epistaxis. "
03/01/2007 - "Retrospective review was performed of 64 individual laser treatments for epistaxis in HHT patients at the University of California, San Diego, Medical Center between 2002 and 2005. "