|3.||Infantile Spasms (West Syndrome)
|4.||Absence Epilepsy (Absence Seizure)
|1.||Striano, Pasquale: 8 articles (08/2014 - 03/2006)|
|2.||Zara, Federico: 8 articles (08/2014 - 05/2002)|
|3.||George, Alfred L: 8 articles (12/2012 - 12/2003)|
|4.||Yamakawa, Kazuhiro: 8 articles (06/2012 - 05/2002)|
|5.||Dulac, Olivier: 7 articles (01/2013 - 03/2003)|
|6.||Escayg, Andrew: 6 articles (03/2011 - 02/2006)|
|7.||Scheffer, Ingrid E: 5 articles (05/2013 - 02/2002)|
|8.||Guerrini, Renzo: 5 articles (09/2011 - 06/2002)|
|9.||Berkovic, S F: 5 articles (06/2011 - 07/2001)|
|10.||Ohmori, Iori: 5 articles (05/2011 - 07/2002)|
|1.||Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
01/01/2009 - "We diagnosed her as having juvenile myoclonus epilepsy and initiated sodium valproate monotherapy, which relieved the symptoms. "
10/01/2002 - "She was diagnosed as having benign myoclonic epilepsy of infancy at 3.5 months of age and treated with valproic acid. "
10/01/2013 - "Valproic acid (VPA), an anticonvulsant and mood-stabilizing drug, is widely used for the treatment of different types of seizures and myoclonic epilepsy. "
09/01/2011 - "A 4.5 years old male with myoclonic epilepsy on Valproic acid (VPA) monotherapy, developed an acute pancreatitis. "
09/01/2008 - "In 5 pediatric patients with severe myoclonic epilepsy and valproic acid-induced liver failure, we identified 1 novel and 4 previously described pathogenic mutations in the linker region of this enzyme. "
|2.||clobazam (HR 376)IBA
11/01/1999 - "Ten of the 20 children with severe myoclonic epilepsy in infancy also responded with clobazam (CLB) as comedication. "
01/01/2007 - "Whereas the studies in adult patients were disappointing, the trials conducted in pediatric populations demonstrated a specific efficacy of STP in severe myoclonic epilepsy in infancy, Dravet syndrome, when combined with valproate and clobazam. "
07/01/2005 - "Although the studies in adult patients were disappointing, the trials conducted in paediatric populations demonstrated a specific efficacy of STP in a severe form of early childhood epilepsy, Dravet syndrome (severe myoclonic epilepsy in infancy), when combined with valproate and clobazam. "
11/01/2002 - "To describe the long term efficacy and tolerance of stiripentol associated with valproate and clobazam in an exhaustive cohort of patients with severe myoclonic epilepsy of infancy (Dravet's syndrome), in which short term efficacy of such a treatment has recently been demonstrated in a placebo-controlled trial. "
04/01/2006 - "A metabolic interaction between stiripentol (STP), an anticonvulsant agent that inhibits the activity of several cytochromes P450 (P450s), and clobazam (CLB), a 1,5-benzodiazepine, used in association with STP in severe myoclonic epilepsy in infancy was observed in vivo. "
|3.||etiracetam (levetiracetam)FDA LinkGeneric
06/01/2010 - "As for other myoclonic epilepsies, levetiracetam appears to be effective for the treatment of LOMEDS, and may be considered as a first line agent for this disorder."
07/17/2007 - "To conduct an open-label, add-on trial on safety and efficacy of levetiracetam in severe myoclonic epilepsy of infancy (SMEI). "
07/17/2007 - "An open-label trial of levetiracetam in severe myoclonic epilepsy of infancy."
07/17/2007 - "Levetiracetam add-on is effective and well tolerated in severe myoclonic epilepsy of infancy. "
01/01/2015 - "Paradoxical exacerbation of myoclonic-astatic seizures by levetiracetam in myoclonic astatic epilepsy."
08/01/2001 - "Stiripentol can be effective in severe myoclonic epilepsy in infancy. "
11/11/2000 - "Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial. "
11/01/2012 - "Stiripentol : in severe myoclonic epilepsy of infancy (dravet syndrome)."
01/01/2015 - "This is an updated version of the original Cochrane review published in Issue 11, 2013.Severe myoclonic epilepsy in infants (SMEI), also known as Dravet syndrome, is a rare, refractory form of epilepsy, for which stiripentol (STP) has been recently licensed as add-on therapy. "
01/01/2013 - "Severe myoclonic epilepsy in infants (SMEI), also known as Dravet syndrome, is a rare, refractory form of epilepsy, for whose treatment stiripentol (STP) has been recently licensed for add-on use. "
|5.||Lennox-Gastaut type Epileptic encephalopathyIBA
05/01/2011 - "No patient with myoclonic-astatic epilepsy or Lennox-Gastaut syndrome was aggravated. "
01/01/2006 - "To identify a specific neuropsychological profile associated with myoclonic astatic epilepsy (MAE) and Lennox-Gastaut syndrome (LGS). "
01/01/2006 - "Neuropsychological findings: myoclonic astatic epilepsy (MAE) and Lennox-Gastaut syndrome (LGS)."
01/01/2006 - "The purpose of this article is to present a short review of the natural history of myoclonic astatic epilepsy (MAE; Doose syndrome) and the Lennox-Gastaut syndrome (LGS). "
01/01/2006 - "The natural history of myoclonic astatic epilepsy (Doose syndrome) and Lennox-Gastaut syndrome."
|6.||Immunoglobulin E (IgE)IBA
04/01/1995 - "We propose that reflex myoclonic epilepsy of infancy (RMEI) is a new age-dependent idiopathic generalized epileptic (IGE) syndrome, with an apparently good prognosis."
11/01/2011 - "Benign myoclonic epilepsy in infancy (BMEI) is a rare syndrome included among idiopathic generalized epilepsies (IGE) and syndromes with age-related onset. "
08/03/2010 - "Epilepsy phenotypes varied widely, including idiopathic generalized epilepsies (IGE) with absence (8/12), myoclonic-astatic epilepsy (2/12), and focal epilepsy (2/12). "
08/01/2009 - "Mutations in the SCN1A gene are found in up to 80% of individuals with severe myoclonic epilepsy of infancy (SMEI), and mutations in KCNQ2 and KCNQ3 were identified in benign familial neonatal convulsions (BFNC) as well as in single families with Rolandic epilepsy (RE) and idiopathic generalized epilepsies (IGE). "
01/01/2005 - "Ten of them were over 50 years, 8 had a diagnosis of juvenile absence epilepsy (JAE); 12--juvenile myoclonic epilepsy (JME) and 16--awakening epilepsy (AE), IGE with isolated generalized tonic-clonic seizures. "
07/01/1975 - "[Polygraphic study of bismuth-induced myoclonic encephalopathy]."
12/01/2002 - "Myoclonic encephalopathy caused by chronic bismuth abuse."
02/01/1990 - "[Myoclonic encephalopathy caused by bismuth]."
03/01/1989 - "[Myoclonic encephalopathy caused by bismuth]."
07/01/1982 - "faecalis, which do not darken in the presence of Bismuth in vitro, and which had been previously isolated from faeces of patients having presented bismuthic myoclonic encephalopathy, were implanted in the digestive tract of axenic rats. "
|8.||Anticonvulsants (Antiepileptic Drugs)IBA
01/01/2015 - "Antiepileptic drugs for the treatment of infants with severe myoclonic epilepsy."
01/01/2013 - "Antiepileptic drugs for the treatment of severe myoclonic epilepsy in infancy."
10/01/2012 - "We describe the case of an 8-year-old girl with early-onset myoclonic epilepsy unresponsive to eight anticonvulsants. "
08/01/2014 - "During the second stage, myoclonic epilepsy manifested (mean age: 51.4 ± 7.2 years) with myoclonic jerks time-locked to diffuse epileptiform abnormalities upon awakening, which was controlled with antiepileptic drugs. "
12/01/2012 - "On the other hand, some myoclonic epilepsies remain refractory to drug treatment and some antiepileptic drugs may exacerbate or even induce myoclonus. "
|9.||lamotrigine (Lamictal)FDA LinkGeneric
09/01/1995 - "Lamotrigine can be helpful for severe myoclonic epilepsy and myoclonic absences. "
03/01/2000 - "In severe myoclonic epilepsy of infancy, there is a nearly constant aggravating effect of lamotrigine. "
01/01/1998 - "Recent evidence indicates that lamotrigine is inappropriate in severe myoclonic epilepsy. "
01/01/1998 - "Severe myoclonic epilepsy of infants usually worsens with lamotrigine, but occasionally, children improve. "
01/01/2013 - "Myoclonic astatic epilepsy (Doose syndrome) - a lamotrigine responsive epilepsy?"
06/01/1997 - "These occurred most often in patients with nonprogressive myoclonic epilepsy; therefore vigabatrin should be used with particular caution in such patients."
11/01/1993 - "Vigabatrin has been shown to aggravate "nonprogressive myoclonic epilepsies." Vigabatrin has been well tolerated in children, with mild drowsiness and agitation being the most commonly reported side effects."
01/01/2006 - "Vigabatrin caused rapidly progressive deterioration in two cases with early myoclonic encephalopathy associated with nonketotic hyperglycinemia."
11/01/1999 - "STP seems to be a promising add-on drug, particularly when combined with CBZ in patients with partial childhood epilepsy refractory to vigabatrin (VGB) and with CLB in patients with severe myoclonic epilepsy in infancy."
12/01/1993 - "Vigabatrin is also effective in infantile spasms, but seems to have negative effects on myoclonic epilepsies and absence seizures. "
08/01/2014 - "We report the successful use of the ketogenic diet in a child with myoclonic astatic epilepsy and type 1 diabetes. "
07/01/2012 - "Myoclonic astatic epilepsy and the use of the ketogenic diet."
05/01/2011 - "Myoclonic astatic epilepsy and the role of the ketogenic diet."
06/01/2006 - "In this prospective study we assess the efficacy and tolerability of the ketogenic diet in patients with myoclonic-astatic epilepsy. "
06/01/2006 - "Ketogenic diet in patients with myoclonic-astatic epilepsy."
|2.||Carbohydrate-Restricted Diet (Low Carbohydrate Diet)
|3.||Renal Dialysis (Hemodialysis)