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Partial Epilepsies (Epilepsy, Partial)

Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
Also Known As:
Epilepsy, Partial; Subclinical Seizure; Epilepsy, Focal; Partial Epilepsy; Simple Partial Seizures; Epilepsies, Partial; Amygdalo-Hippocampal Epilepsy; Benign Focal Epilepsy, Childhood; Benign Occipital Epilepsy; Benign Occipital Epilepsy, Childhood; Childhood Benign Focal Epilepsy; Childhood Benign Occipital Epilepsy; Epilepsy, Benign Occipital; Epilepsy, Localization-Related; Occipital Lobe Epilepsy; Partial Seizures, Simple, Consciousness Preserved; Rhinencephalic Epilepsy; Seizure Disorder, Focal; Uncinate Seizures; Abdominal Epilepsies; Amygdalo-Hippocampal Epilepsies; Benign Occipital Epilepsies; Digestive Epilepsies; Disorders, Focal Seizure; Disorders, Partial Seizure; Epilepsies, Abdominal; Epilepsies, Amygdalo-Hippocampal; Epilepsies, Benign Occipital; Epilepsies, Digestive; Epilepsies, Focal; Epilepsies, Gelastic; Epilepsies, Localization-Related; Epilepsies, Occipital Lobe; Epilepsies, Rhinencephalic; Epilepsies, Simple Partial; Epilepsy, Abdominal; Focal Epilepsies; Focal Epilepsy; Focal Seizure Disorders; Gelastic Epilepsies; Lobe Epilepsy, Occipital; Localization-Related Epilepsies; Localization-Related Epilepsy; Occipital Epilepsies, Benign; Occipital Epilepsy, Benign; Occipital Lobe Epilepsies; Partial Epilepsies, Simple; Partial Seizure Disorders; Partial Seizures, Simple; Rhinencephalic Epilepsies; Seizure Disorders, Focal; Seizure Disorders, Partial; Seizure, Subclinical; Seizure, Uncinate; Seizures, Simple Partial; Seizures, Subclinical; Seizures, Uncinate; Simple Partial Epilepsies; Subclinical Seizures; Abdominal Epilepsy; Digestive Epilepsy; Epilepsy, Simple Partial; Focal Seizure Disorder; Gelastic Epilepsy; Partial Seizure Disorder; Seizure Disorder, Partial
Networked: 1729 relevant articles (173 outcomes, 338 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Seizures (Seizure)
2. Epilepsy (Aura)
3. Generalized Epilepsy
4. Infantile Spasms (West Syndrome)
5. Temporal Lobe Epilepsy

Experts

1. Marson, Anthony G: 23 articles (08/2015 - 03/2007)
2. Marson, A G: 15 articles (01/2008 - 01/2000)
3. Ryvlin, Philippe: 13 articles (07/2015 - 09/2004)
4. Perucca, Emilio: 11 articles (09/2015 - 03/2005)
5. Brodie, Martin J: 10 articles (11/2015 - 01/2004)
6. Verrotti, Alberto: 10 articles (01/2015 - 11/2005)
7. Hutton, Jane L: 10 articles (09/2014 - 01/2008)
8. Matsumoto, Riki: 9 articles (10/2015 - 05/2004)
9. Schulze-Bonhage, A: 9 articles (04/2013 - 02/2000)
10. Elger, C E: 9 articles (10/2012 - 02/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Partial Epilepsies:
1. Carbamazepine (Tegretol)FDA LinkGeneric
2. topiramate (Topamax)FDA LinkGeneric
3. etiracetam (levetiracetam)FDA LinkGeneric
4. Valproic Acid (Valproate, Semisodium)FDA LinkGeneric
5. lamotrigine (Lamictal)FDA LinkGeneric
6. zonisamide (Zonegran)FDA LinkGeneric
7. Anticonvulsants (Antiepileptic Drugs)IBA
8. gabapentin (Neurontin)FDA LinkGeneric
9. oxcarbazepine (Trileptal)FDA LinkGeneric
10. Phenytoin (Dilantin)FDA LinkGeneric

Therapies and Procedures

1. Electrodes (Electrode)
2. Vagus Nerve Stimulation
3. Drug Therapy (Chemotherapy)
4. Ketogenic Diet
5. Psychology Biofeedback (Biofeedback)
01/01/2001 - "Measures of depression and locus of control were administered to 20 patients with refractory partial epilepsy before and after biofeedback treatment. "
10/01/1997 - "Sixteen patients with partial epilepsy learned to produce positive or negative slow cortical potential shifts in a biofeedback condition during 20 consecutive training sessions. "
11/01/1996 - "Twenty sessions of biofeedback training were carried out with 12 drug-resistant patients with focal epilepsy who learned to produce either negative or positive shifts of their slow cortical potentials (SCPs) at vertex. "
01/01/2011 - "In this systematic review we present information relating to the effectiveness and safety of the following interventions: antiepileptic drugs after a single seizure; monotherapy for partial epilepsy using carbamazepine, gabapentin, lamotrigine, levetiracetam, phenobarbital, phenytoin, sodium valproate, or topiramate; addition of second-line drugs for drug-resistant partial epilepsy (allopurinol, eslicarbazepine, gabapentin, lacosamide, lamotrigine, levetiracetam, losigamone, oxcarbazepine, retigabine, tiagabine, topiramate, vigabatrin, or zonisamide); antiepileptic drug withdrawal for people with partial or generalised epilepsy who are in remission; behavioural and psychological treatments for partial or generalised epilepsy (biofeedback, cognitive behavioural therapy (CBT), educational programmes, family counselling, relaxation therapy (alone or plus behavioural modification therapy, yoga); and surgery for drug-resistant temporal lobe epilepsy ( lesionectomy, temporal lobectomy, vagus nerve stimulation as adjunctive therapy)."
01/01/2010 - "In this systematic review we present information relating to the effectiveness and safety of the following interventions: antiepileptic drugs after a single seizure; monotherapy for partial epilepsy using carbamazepine, gabapentin, lamotrigine, levetiracetam, phenobarbital, phenytoin, sodium valproate, or topiramate; addition of second-line drugs for drug-resistant partial epilepsy (allopurinol, eslicarbazepine, gabapentin, lacosamide, lamotrigine, levetiracetam, losigamone, oxcarbazepine, retigabine, tiagabine, topiramate, vigabatrin, or zonisamide); antiepileptic drug withdrawal for people with partial or generalised epilepsy who are in remission; behavioural and psychological treatments for partial or generalised epilepsy (biofeedback, cognitive behavioural therapy (CBT), educational programmes, family counselling, relaxation therapy (alone or plus behavioural modification therapy, yoga); and surgery for drug-resistant temporal lobe epilepsy ( lesionectomy, temporal lobectomy, vagus nerve stimulation as adjunctive therapy)."