|5.||Abdominal Pain (Pain, Abdominal)
|1.||Aktories, Klaus: 9 articles (04/2014 - 01/2003)|
|2.||Gerhard, Ralf: 5 articles (02/2015 - 01/2003)|
|3.||Just, Ingo: 4 articles (03/2011 - 01/2003)|
|4.||Pothoulakis, Charalabos: 3 articles (10/2011 - 06/2004)|
|5.||Giesemann, Torsten: 3 articles (02/2009 - 04/2006)|
|6.||Feng, Hanping: 2 articles (04/2015 - 03/2011)|
|7.||Papatheodorou, Panagiotis: 2 articles (04/2014 - 01/2013)|
|8.||Kim, Ho: 2 articles (10/2011 - 07/2008)|
|9.||Lee, Dong-Gun: 2 articles (09/2011 - 01/2007)|
|10.||Min, Woo-Sung: 2 articles (09/2011 - 01/2007)|
12/16/1978 - "The results suggest that vancomycin eliminates toxin-producing Cl difficile from the colon and is associated with rapid clinical and histological improvement in patients with pseudomembranous colitis."
11/01/1982 - "Vancomycin is recommended for treatment of pseudomembranous colitis when removal of the offending antimicrobial agent does not result in clinical improvement."
09/01/1980 - "After reporting the case of a child suffering from pseudomembranous colitis (PMC) rapidly cured by vancomycin, the authors present current knowledge which had led to this new mode of therapy. "
12/16/1978 - "The efficacy of vancomycin in pseudomembranous colitis was assessed in a prospective randomised controlled trial. "
05/01/1986 - "The diagnosis of antibiotic-associated colitis was excluded in our patient by the negative stool examination for Clostridium difficile toxin, the failure to obtain supportive features on rectal biopsy, and the failure to demonstrate sigmoidoscopic improvement with vancomycin therapy. "
|2.||Anti-Bacterial Agents (Antibiotics)IBA
01/01/1988 - "The disease, ironically, has been most effectively treated with antibiotics, although some of the newer methods of treatment such as the replacement of the bowel flora may prove more beneficial for patients who continue to relapse with pseudomembranous colitis. "
04/01/1996 - "Apart from one case of unconfirmed pseudomembranous colitis, none of the other 2468 deaths that occurred in these studies was attributed to the antibiotics. "
01/01/2013 - "Similarly, antibiotic treatment is also a matter of discussion due to the potential deleterious role of antibiotics in pseudomembranous colitis."
03/01/2012 - "After the surgery, during the antibiotic treatment, the patient developed pseudomembranous colitis treated with specific antibiotics. "
04/15/2011 - "Clostridium difficile is a Gram-positive obligate anaerobic pathogen that causes pseudomembranous colitis in antibiotics-treated individuals. "
|3.||Cholestyramine Resin (Questran)FDA LinkGeneric
03/09/2001 - "A potential therapy for antibiotic-associated pseudomembranous colitis is to bind Clostridium difficile toxins A and B using cholestyramine, a hydrophobic anion exchange medium. "
01/01/1980 - "These data suggest that the therapeutic benefit of cholestyramine in some patients with antibiotic-associated pseudomembranous colitis is due to its binding of the C. "
08/01/1979 - "Cholestyramine therapy for antibiotic-associated colitis."
03/01/1979 - "Seven patients treated with oral cholestyramine for antibiotic-associated pseudomembranous colitis are reported. "
09/01/1978 - "Treatment of antibiotic-associated pseudomembranous colitis with cholestyramine resin."
|4.||Clindamycin (Cleocin)FDA LinkGeneric
01/01/1992 - "In the present studies, we tested whether yogurt ingestion could prevent or ameliorate antibiotic associated colitis in the clindamycin-treated hamster model. "
03/01/1977 - "Many studies have shown that clindamycin may cause pseudomembranous colitis, a potentially fatal complication. "
04/01/2006 - "There are two reports of topical clindamycin causing pseudomembranous colitis after long-term and widespread usage. "
09/01/1998 - "With respect to clindamycin, the suggested association between its topical use and the occurrence of pseudomembranous colitis appears not to be of clinical relevance. "
09/02/1995 - "Clindamycin and pseudomembranous colitis."
|5.||Metronidazole (Metric)FDA LinkGeneric
05/01/1982 - "Our experience with metronidazole shows that it is an effective treatment for antibiotic-associated pseudomembranous colitis. "
04/01/1998 - "This study was designed to determine whether oral metronidazole, as part of preoperative bowel preparation, prevents or decreases incidence of antibiotic-associated colitis after elective colonic and rectal procedures. "
04/01/2002 - "This enzyme could be the target for metronidazole in the treatment of pseudomembranous enterocolitis caused by C. "
11/01/1988 - "Failure of parenteral metronidazole in the treatment of pseudomembranous colitis."
01/01/1988 - "Multidisciplinary cost-containment program promoting oral metronidazole for treatment of antibiotic-associated colitis."
|6.||Lincomycin (Lincocin)FDA Link
12/01/1983 - "The patient also had pseudomembranous enterocolitis, a well-known side effect of lincomycin."
03/03/1981 - "[Pseudomembranous colitis following an antibiotic treatment with lincomycin report of two cases (author's transl)]."
11/04/1978 - "Lincomycin-resistant Clostridium sporogenes obtained from the stools of a patient with lincomycin-associated pseudomembranous colitis produced a heat-stable cytotoxin in low titre when grown in chopped meat medium. "
08/01/1977 - "4 Two patients developed pseudomembranous colitis after parenteral lincomycin."
02/19/1977 - "One patient developed pseudomembranous colitis associated with two prolonged courses of lincomycin therapy. "
|7.||Bacitracin (Baci-Rx)FDA LinkGeneric
10/01/1980 - "Two patients with antibiotic-associated pseudomembranous colitis, and stool positive for Clostridium difficile cytotoxin were successfully treated with oral bacitracin. "
10/01/1980 - "Bacitracin therapy in antibiotic-associated pseudomembranous colitis."
06/01/1980 - "Four cases of antibiotic-associated colitis and diarrhea caused by Clostridium difficile were successfully treated with oral bacitracin, 25,000 units four times daily for 7-10 days. "
06/01/1980 - "Bacitracin treatment of antibiotic-associated colitis and diarrhea caused by Clostridium difficile toxin."
11/01/1985 - "A randomized double-blind study was carried out in patients with unresolving antibiotic-associated colitis due to Clostridium difficile, to compare the effect of bacitracin (80,000 U/day) with vancomycin (500 mg/day) on the resolution of symptoms, clearance of organism, and prevention of relapse. "
|8.||Antineoplastic Agents (Antineoplastics)IBA
12/01/2010 - "If a patient treated with immunosuppressive agents or antineoplastic agents complains diarrhea, fever or abdominal pain and has not improved with conservative care, pseudomembranous colitis should be taken into account as a differential diagnosis and prompt treatment is required for better prognosis."
02/01/1984 - "Eight patients are presented in whom treatment with antineoplastic agents, in particular the folic acid antagonist methotrexate, precipitated Clostridium difficile-related diarrhoea and pseudomembranous colitis. "
01/01/1984 - "In our study we evaluated the in vitro activity of three commonly used antineoplastic drugs (Daunorubicin, Cytosine arabinoside, Methotrexate) against aerobic and anaerobic intestinal bacteria and Clostridium difficile that is the aetiological agent of pseudomembranous colitis. "
01/01/2000 - "The concomitant antimicrobial properties of antineoplastic agents may play a role in causing pseudomembranous colitis, which has been documented for cisplatin, cyclophosphamide and 5-fluorouracil. "
|9.||Rifampin (Rifampicin)FDA LinkGeneric
06/01/1997 - "Delayed onset of pseudomembranous colitis after rifampin therapy."
12/01/2011 - "Pseudomembranous colitis (PMC) is known to be associated with antibiotic treatment, but is not commonly related to antitubercular (anti-TB) agent, rifampin. "
12/01/2011 - "Rifampin-induced Pseudomembranous Colitis with Rectosigmoid Sparing."
01/01/2011 - "Development of pseudomembranous colitis four months after initiation of rifampicin."
08/01/2009 - "Rifampin-associated pseudomembranous colitis."
06/02/2015 - "The receptor is highly expressed on the surface epithelium of the human colon and was observed to colocalize with TcdB in both an explant model and in tissue from a patient with pseudomembranous colitis. "
08/01/2007 - "Clostridium difficile toxins A and B (TcdA and TcdB) are the causative agents of antibiotic-associated pseudomembranous colitis. "
03/01/2001 - "difficile, TcdA-10463 (TcdA) and TcdB-10463 (TcdB), and a model intestinal epithelial cell line to characterize their influence on tight-junction (TJ) organization and hence to analyze the mechanisms by which they contribute to the enhanced paracellular permeability and disease pathophysiology of pseudomembranous colitis. "
03/01/2011 - "Toxin A (TcdA) and toxin B (TcdB) are the major virulence factors of Clostridium difficile and are the causative agents for clinical symptoms, such as secretory diarrhoea and pseudomembranous colitis. "
01/01/2001 - "TcdB from Clostridium difficile glucosylates small GTPases (Rho, Rac, and Cdc42) and is an important virulence factor in the human disease pseudomembranous colitis. "
01/01/1983 - "Double-contrast enema in antibiotic-related pseudomembranous colitis."
10/01/1960 - "Further observations on the value of donor fecal enemata as an adjunct in the treatment of pseudomembranous enterocolitis."
11/01/1958 - "Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis."
09/01/2014 - "The following Medical Subject Headings terms and keywords were used alone or in combination: Clostridium difficile; Clostridium infection; pseudomembranous colitis; feces; stools; fecal suspension; fecal transplantation; fecal transfer; fecal infusion; microbiota; bacteriotherapy; enema; nasogastric tube; colonoscopy; gastroscopy; fecal donation; donor. "
04/01/2012 - "The Cochrane Library, PubMed, EMBASE, CINAHL, Biological Abstracts, BIOSIS Previews and Web of Science were searched using the following Medical Subject Headings (MeSH) terms and keywords, alone or in combination: Clostridium infections/Clostridium difficile/pseudomembranous/colitis/faeces/rectal/colon flora/gastrointestinal/nasogastric tube/enema/donor/transplant/infusion/bacteriotherapy/human probiotic infusion. "
05/01/1993 - "Based on experimental evidence in animals showing that the oral administration of Saccharomyces boulardii is effective in reducing morbidity and mortality due to Clostridium difficile-induced pseudomembranous colitis, we conducted an open trial to examine the effects of the living yeast, given as primary therapy, in a selected group of infants and children with persistent intestinal symptoms related to toxinogenic C. "
11/01/1981 - "Unfortunately, oral administration is associated with pseudomembranous colitis in up to 10% of patients; consequently, it is no longer a generally accepted form of acne therapy. "
09/01/1990 - "On colonoscopic examination, 5 patients were diagnosed as having developed pseudomembranous colitis, and were treated by oral administrations of Vancomycin. "
07/01/1986 - "Although vancomycin is not appreciably absorbed from the intact gastrointestinal tract, several recent case reports have documented the attainment of therapeutic and potentially toxic vancomycin serum concentrations following oral administration to patients with pseudomembranous colitis. "
11/01/2009 - "To report a case in which the serum concentration of vancomycin (VCM) reached the supratherapeutic range following oral administration in a patient with severe pseudomembranous colitis and renal insufficiency. "
|3.||Drug Therapy (Chemotherapy)
01/01/2013 - "Development of nonantibiotic-associated pseudomembranous colitis has been reported in patients receiving chemotherapy. "
09/01/2006 - "Pseudomembranous colitis also demonstrates marked wall thickening and, occasionally, skip areas but is associated with broad-spectrum antibiotic treatment or chemotherapy. "
01/18/1992 - "Pseudomembranous colitis complicating chemotherapy."
07/01/1991 - "Decision analysis plus a drug therapy review had no greater impact on pharmacists' opinions on the selection of drug therapy for pseudomembranous colitis than did the review alone. "
05/01/1985 - "The diagnosis, etiology, epidemiology, and drug therapy of antibiotic-associated pseudomembranous colitis (AAPMC) are reviewed. "
10/01/2008 - "[Percutaneous endoscopic colostomy for treatment of an antibiotic-induced pseudomembranous colitis]."
06/01/1995 - "Pseudomembranous colitis in a patient with a colostomy."
03/01/1994 - "Pseudomembranous colitis as a cause of early colostomy dysfunction."
08/12/1978 - "Pseudomembranous colitis in a colostomy."
07/01/2004 - "Colostomy with vancomycin administration as an effective treatment for toxic megacolon associated with fulminant pseudomembranous colitis: a case report."