Endometritis

10/01/1986 - "Antibiotic application in 79% of all these patients led to a significant reduction in puerperal febrile morbidity and endomyometritis. "
11/01/1983 - "There was a significant reduction in the incidence of postoperative endomyometritis in the group prophylactic antibiotics (12/45, 26.7%) compared to the control group not given prophylactic antibiotics (20/39, 51.3%), p less than 0.05. "
01/01/1986 - "Administration of antibiotics by irrigation is equally effective in preventing postoperative febrile morbidity and endomyometritis as intravenous dosing and a combination of intravenous and irrigation. "
01/01/2023 - "The impact of antibiotic-cured chronic endometritis (CE) on perinatal outcomes of patients conceived with frozen embryo transfer (FET) was unclear. "
01/01/2023 - "Impact of antibiotic cured chronic endometritis on perinatal outcomes: Re-evaluation of a cohort study with a detailed follow-up."

06/01/1996 - "In patients with postpartum endometritis, once-daily gentamicin dosing provides consistently high peak serum levels of gentamicin, requires less nurse tasking time, costs less, and is as effective as the 8-hour dosing regimen."
06/01/1996 - "To evaluate whether once-daily gentamicin dosing is as effective as the traditional 8-hour regimen for the treatment of postpartum endometritis. "
02/01/1989 - "Postpartum women receiving gentamicin for endometritis were studied to determine if selective determination of gentamicin serum levels was cost-effective in terms of safety and efficacy. "
11/01/2020 - "The aim of the present study was to use PGF2α and/or gentamicin 10% for treatment of endometritis and to determine biochemical parameters in serum that could be used to diagnose endometritis in buffalo cows. "
03/01/2001 - "In this study 10 women with post partum endometritis were given once daily intravenous gentamicin (4 mg/kg ideal body weight) followed at a later day by a similar intramuscular dose. "

05/01/2023 - "In the present study, we determined the protective effects of FXR on lipopolysaccharide (LPS)-induced endometritis in mice and the underlying mechanisms. "
01/01/2022 - "This study investigated the protective effects and mechanisms of KYNA using a mouse model of against lipopolysaccharide (LPS)-induced endometritis. "
08/01/2018 - "In this study, we reported the protective effects and mechanism of SSA on lipopolysaccharide (LPS)-induced endometritis in mice. "
11/01/2023 - "Here, the protective effects of NF on lipopolysaccharide (LPS)-induced endometritis in mice were investigated in our research. "
12/01/2022 - "Enhanced expression of miR-26a ameliorates lipopolysaccharide-induced endometritis by targeting MAP3K8 to inactivate MAPK signaling pathway."

05/01/1981 - "The levels of clindamycin in the above-mentioned tests state how samples were compared with the minimal inhibitory concentration of the offending anaerobic pathogens in cases of endometritis."
07/01/1984 - "hominis has been strongly linked to postabortal fever and to postpartum fever and endometritis, our results indicate that clindamycin should be evaluated in treatment trials in pregnancy aimed at prevention of M. "
01/03/1981 - "Patients with endometritis or adnexitis usually received clindamycin in combination with an aminopenicillin. "
09/01/1991 - "The addition of clindamycin to provide anaerobic coverage for intra-amnionic infection does not significantly alter the incidence of endometritis in women delivered by cesarean section, although it may have an impact on women delivering vaginally."
01/01/2003 - "The objective of the study was to evaluate the efficacy of gentamicin and clindamycin given once daily versus the more common 8-hour dosing regimen for the treatment of postpartum endometritis. "

03/01/2006 - "Ampicillin has been reported to be an effective AMA in reducing post-partum endometritis and our observation also corroborates with this finding."
01/01/1996 - "Group B streptococcal prophylaxis with a short course of intravenous ampicillin increases the risk of postpartum endomyometritis in patients with premature PROM."
01/01/1996 - "There was a significantly higher incidence of postpartum endomyometritis among the patients who received ampicillin (62% vs. 22%; P < 0.01). "
06/01/2020 - "All three patients had an infection with ampicillin-susceptible Enterococcus faecalis; one patient had post-partum endometritis, one had urosepsis and one had a complex polymicrobial bone and joint infection. "
06/01/2023 - "Among women who received ampicillin alone compared with dual therapy, rates were higher of endometritis (16.5% vs. 3.2%, p<0.001), neonatal early onset sepsis (7.5% vs. 0%, p=0.03), Enterobacteriaceae positive placental swab culture (67.9% vs. 15.7%, p<0.001), and histopathological subchorionitis (25.3% vs. 8.0%, p=0.008). "

01/01/2019 - "Rankings of vaginal preparations indicated that povidone-iodine 1% had the highest probability (72.7%) of being the most effective treatment for the prevention of endometritis. "
11/01/2012 - "The purpose of the present study was to determine whether the vaginal preparation with povidone-iodine prior to caesarean delivery decreased the incidence of postpartum endometritis. "
01/01/2019 - "Subgroup analyses also found that povidone-iodine significantly reduced risk of endometritis for women in labor (odds ratio, 0.42; 95% confidence interval, 0.20-0.88; 5 studies/1211 women), with ruptured membranes(odds ratio, 0.21; 95% confidence interval, 0.10-0.44; 4 studies/476 women), and undergoing planned cesarean delivery (odds ratio, 0.39; 95% confidence interval, 0.27-0.57; 8 studies/1825 women). "
11/01/2022 - "Regarding post-cesarean endometritis, we found that povidone-iodine had the highest significant risk reduction compared to "no vaginal cleaning" (RR = 0.08, 95% CI [0.01, 0.69]). "
05/03/2016 - "Thus, an intrauterine infusion of 2.0% PVP-I was better than 0.5% in treating clinical endometritis in these dairy cattle. "

01/01/2021 - "These results suggest that building an environment where there is an increase in bacteria that are generally recognized as beneficial, such as Lactobacillus, may be one possible solution to reduce the abundance of Trueperella and control endometritis."
01/15/2017 - "Chlorhexidine gluconate solution is a potent antimicrobial and therefore could be used effectively for treatment of endometritis, but historically this substance has been implicated as irritating to mucous membranes, including the endometrium of the mare. "
01/01/2019 - "Vaginal cleansing with povidone-iodine solution 10% prior to elective CS appears to be effective in reducing rates of post-CS infectious morbidity mainly endometritis."
01/15/2021 - "This study investigated the efficacy of intrauterine infusion of a chitosan solution (CHT) on uterine recovery in early postpartum dairy cows with or without endometritis, and their subsequent reproductive performance. "
01/15/2021 - "Effects of Intrauterine Infusion of a Chitosan Solution on Recovery and Subsequent Reproductive Performance of Early Postpartum Dairy Cows with Endometritis: A Pilot Field Trial."

11/01/2001 - "To estimate the efficacy of preoperative administration of intravaginal metronidazole for the prevention of postcesarean endometritis. "
10/01/2004 - "Because these organisms were strongly associated with endometritis, we recommend that all women with PID be treated with regimens that include metronidazole."
11/01/2001 - "The preoperative administration of 5 g of intravaginal metronidazole gel appears to reduce the incidence of postcesarean endometritis."
11/01/2001 - "Of 112 patients receiving metronidazole, eight (7%) developed postcesarean endometritis, compared with 19 of 112 (17%) of those receiving placebo gel (relative risk 0.42, 95% confidence interval 0.19, 0.92). "
11/01/2001 - "Adjunctive intravaginal metronidazole for the prevention of postcesarean endometritis: a randomized controlled trial."

09/10/2023 - "The risk of endometritis was 1.5% in the azithromycin group and 2.3% in the placebo group (RR 0.64, 95% CI 0.55-0.75), and the evidence certainty was high. "
01/01/2020 - "Two cohort studies (n = 13,809) found that azithromycin significantly reduces the risk of endometritis RR [0.16; 95 %, 0.04-0.62] P = 0.008, however significant heterogeneity was seen. "
01/01/2008 - "Extended-spectrum antibiotic prophylaxis involving the addition of azithromycin to standard narrow-spectrum prophylaxis was associated with a significant reduction in postcesarean endometritis. "
03/01/2022 - "Our meta-analysis of RCTs showed that addition of azithromycin as prophylaxis in CD significantly reduced the risk of endometritis [relative risk (RR) = 0.62, 95% confidence interval (CI) 0.49-0.79; P < 0.0001] and wound infection (RR = 0.40, 95% CI 0.27-0.58; P < 0.00001). "
01/01/2016 - "There were significant differences between the azithromycin group and the placebo group in rates of endometritis (3.8% vs. 6.1%, P=0.02), wound infection (2.4% vs. 6.6%, P<0.001), and serious maternal adverse events (1.5% vs. 2.9%, P=0.03). "

09/25/2023 - "Our analysis showed statistically significant lower levels of uterine cytokines TNF-α (p = 0.001) and IL-1beta (p = 0.000) in the KIR AA genotype group as compared to KIR AB and BB among study participants with chronic endometritis. "
04/01/2019 - "Taken together, our results suggested that let-7c ameliorates LPS-induced endometritis by attenuating the expression of pro-inflammatory cytokines via inhibition of the activation of NF-κB."
01/01/2022 - "This study proved that the mechanism of action of IOP is to inhibit the TLR4/NF-κB signaling pathway to reduce the release of pro-inflammatory cytokines from body cells, thereby alleviating the symptoms of endometritis induced by LPS. "
06/01/2019 - "The objective of the study was to investigate the role of pro-inflammatory cytokines in the pathogenesis of endometritis in buffaloes, which can lead to early diagnosis of endometritis. "
06/01/2019 - "Pro-inflammatory cytokine expression studies of subclinical and clinical endometritis in endometrial tissues of buffaloes."

12/01/1980 - "Patients who underwent primary cesarean section were at significantly greater risk of developing postoperative endometritis than were patients undergoing a repeat procedure. "
05/01/1980 - "Therefore, patients with post-cesarean section endomyometritis have less febrile morbidity if they are initially treated with a drug effective against anaerobic bacteria, especially B fragilis."
07/01/1991 - "A retrospective analysis of 1000 case histories of women who delivered by cesarean section has helped define the principal factors of postsurgical endometritis risk. "
04/01/2021 - "The aim of the study was to compare the rates of postpartum endometritis due to uterine cleaning and no cleaning in patients delivered by elective cesarean section. "
01/18/2012 - "The use of amnioinfusion for potential or suspected umbilical cord compression may be of considerable benefit to mother and baby by reducing the occurrence of variable FHR decelerations, improving short-term measures of neonatal outcome, reducing maternal postpartum endometritis and lowering the use of caesarean section, although there were methodological limitations to the trials reviewed here. "

10/18/2004 - "Once uncomplicated endometritis has clinically improved with intravenous therapy, oral therapy is not needed."
01/01/2002 - "Once uncomplicated endometritis has clinically improved with intravenous therapy, oral therapy is not needed."
01/01/2000 - "Once uncomplicated endometritis has clinically improved with intravenous therapy, oral therapy is not needed."
10/01/2013 - "The objectives of the current study were to investigate the efficacy of PGF₂α as a therapy to reduce the prevalence of subclinical endometritis and improve pregnancy per artificial insemination (P/AI) in cows subjected to a timed artificial insemination (AI) program. "
05/01/2003 - "In this study, we wanted to establish a method for cryopreservation of functionally competent neutrophils for an intended local endometritis therapy in mares. "

09/01/1990 - "Efficacy of antibiotic prophylaxis in preventing postoperative endometritis in certain high-risk patients has been well documented. "
10/20/2014 - "There are no randomized controlled trials to evaluate the effectiveness of antibiotic prophylaxis to prevent endometritis after manual removal of placenta in vaginal birth."
04/19/2006 - "There are no randomized controlled trials to evaluate the effectiveness of antibiotic prophylaxis to prevent endometritis after manual removal of placenta in vaginal birth."
05/01/1985 - "The literature review shows multiple prospective well-designed and executed studies that demonstrate reliable decreases in the incidence of endometritis with short course antibiotic prophylaxis. "
07/01/2023 - "Uterine exploration or instrumentation increases the risk of postpartum endometritis and requires antibiotic prophylaxis. "

01/20/2021 - "Outcome study of five cases receiving in vitro fertilization after treatment of intrauterine platelet-rich plasma (PRP) for chronic endometritis."
03/01/2018 - "Histopathological lesions in uterus showed efficient induction of endometritis by presence of inflammatory cells which are lessened effectively after treatment with Eucalyptus leaves extract. "
04/01/2014 - "The per-pregnancy LBR for the treated chronic endometritis group was 7% (7/98) before treatment versus 56% (28/50) after treatment. "
01/01/2014 - "Echotexture parameters determined by the evaluation of sonographic B-mode images reflect changes in the endometrium and could be used for the evaluation of the recovery period after treatment of endometritis."
01/01/2014 - "Evaluation of endometrial echotexture and cervical cytology in cows during and after treatment of endometritis."

01/01/1982 - "The short-term and long-term prophylaxes were equally effective in reducing morbidity, assessed by postoperative temperatures, presence or absence of endometritis, and duration of postoperative hospital stay."
07/16/2008 - "Manual removal of the placenta was associated with more endometritis (relative risk (RR) 1.64, 95% confidence interval (CI) 1.42 to 1.90; 4134 women, 13 trials); more blood loss (ml) (weighted mean difference (WMD) 94.42 ml, 95% CI 17.19 to 171.64; 2001 women, eight trials); more blood loss > 1000 ml (RR 1.81, 95% CI 1.44 to 2.28; 872 women, two trials); lower haematocrit after delivery (%) (WMD -1.55, 95% CI -3.09 to -0.01; 384 women, two trials); greater haematocrit fall after delivery (%) (WMD 0.39, 95% CI 0.00 to 0.78; 1777 women, five trials); longer duration of hospital stay (days) (WMD 0.39 days, 95% CI 0.17 to 0.61; 546 women, three trials). "
01/01/2017 - "The quality of the evidence using GRADE was low for both endometritis and maternal length of stay. "
06/01/2016 - "The most frequent complications were haemorrhage, transfusion, length of stay >7 days, and endometritis. "
10/13/2014 - "The quality of the evidence using GRADE was low for both endometritis and maternal length of stay. "