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Myelin Basic Proteins

A group of 7 proteins produced from a single gene by alternate splicing found in central and peripheral nervous system myelin. The major basic protein (MBP) has long been of interest because it is the antigen, that, when injected into an animal, elicits a cellular immune response that produces the CNS autoimmune disease called experimental allergic encephalomyelitis (ENCEPHALOMYELITIS, ALLERGIC). In the peripheral nervous system, myelin basic protein 18.5-kDa is often referred to as the P1 protein. (From Siegel et al., Basic Neurochemistry, 5th ed, p130, 133)
Also Known As:
Basic Protein, Encephalitogenic; Basic Proteins, Encephalitogenic; Encephalitogenic Basic Protein; Neuritogenic Protein; Protein, Encephalitogenic Basic; Proteins, Encephalitogenic Basic; Basic Proteins, Myelin; Protein, Neuritogenic; Proteins, Myelin Basic; Encephalitogenic Basic Proteins
Networked: 43 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Hattori, Nobutaka: 1 article (05/2013)
2. Hatano, Taku: 1 article (05/2013)
3. Sasaki, Makoto: 1 article (05/2013)
4. Hori, Masaaki: 1 article (05/2013)
5. Saito, Fumine: 1 article (05/2013)
6. Aoki, Shigeki: 1 article (05/2013)
7. Kawamura, Miwako: 1 article (05/2013)
8. Toyoshima, Y: 1 article (11/2009)
9. Nishizawa, M: 1 article (11/2009)
10. Tan, C-F: 1 article (11/2009)

Related Diseases

1. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
2. Neoplasms (Cancer)
3. Autoimmune Diseases (Autoimmune Disease)
4. Granular Cell Tumor
5. Neurofibroma

Related Drugs and Biologics

1. Antigens
2. Myelin P2 Protein
3. Horseradish Peroxidase
4. Antibodies
5. Complementarity Determining Regions (Complementarity Determining Region)
6. Amyloid beta-Protein Precursor (Amyloid Protein Precursor)
7. Transferrin (beta 2 Transferrin)
8. Proteins (Proteins, Gene)
9. Protein Kinase C
10. Phorbol Esters