Contagious Ecthyma (Orf)

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6373 relevant articles (24 outcomes, 151 trials/studies) found for this Disease

Description: An infectious dermatitis of sheep and goats, affecting primarily the muzzle and lips. It is caused by a poxvirus and may be transmitted to man.

Also Known As:

Orf; Ecthyma, Contagious; Contagious Pustular Dermatitides; Dermatitides, Contagious Pustular; Pustular Dermatitides, Contagious; Pustular Dermatitis, Contagious; Contagious Pustular Dermatitis; Dermatitis, Contagious Pustular

Relationship Network

Disease Context: Research Results

Virus Diseases: 1311

DNA Virus Infections: 22

Poxviridae Infections: 64

Contagious Ecthyma: 6373

Animal Diseases: 110

Sheep Diseases: 5

Contagious Ecthyma: 6373

Related Diseases

1.	Molluscum Contagiosum
2.	Poxviridae Infections
3.	Infection
4.	Papilloma (Papillomatosis)
5.	Retroviridae Infections (Infection, Retrovirus)

Experts

1.	Pistello, Mauro: 2 articles (05/2008 - 09/2006)
2.	Wolff, José Luiz Caldas: 1 article (10/2008)
3.	Romano, Camila Malta: 1 article (10/2008)
4.	Yeda, Fernanda Peres: 1 article (10/2008)
5.	de Castro Oliveira, Juliana Velasco: 1 article (10/2008)
6.	Iamarino, Atila: 1 article (10/2008)
7.	de Melo, Fernando Lucas: 1 article (10/2008)
8.	Hársi, Charlotte Marianna: 1 article (10/2008)
9.	de Andrade Zanotto, Paolo Marinho: 1 article (10/2008)
10.	Rizzi, Thais Sampaio: 1 article (10/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Contagious Ecthyma:

1.	cidofovir (Vistide)FDA Link 08/01/2001 - "A case of human orf in an immunocompromised patient treated successfully with cidofovir cream." 11/01/2003 - "Treatment of orf poxvirus lesion with cidofovir cream." 12/01/2000 - "Three parapoxviruses which cause orf or related diseases in humans and animals and the orthopoxvirus, vaccinia virus, were tested for their in vitro sensitivity to cidofovir" 07/01/2002 - "In humans, cidofovir has been used successfully in the treatment, by both the topical and intravenous route, of recalcitrant molluscum contagiosum and orf in immunocompromised patients" 12/01/2005 - "These findings provide a rationale for the use of HPMPC and other ANPs in the treatment of orf (contagious ecthyma) in humans and animals." Order ALL the reference details at left...
2.	Proteins (Proteins, Gene)IBA 09/01/2008 - "Identification of highly expressed, soluble proteins using an improved, high-throughput pooled ORF expression technology." 06/01/2008 - "Experiments undertaken in this study were intended to confirm the sequence-based gene allocation of JPV and to determine if proteins encoded by the SH gene, the novel TM gene and ORF-X are expressed" 09/01/2007 - "In this study, the virulence of 2b proteins from subgroup IB strains was analysed using four intraspecies hybrid viruses, which were generated by precise replacement of the 2b open reading frame (ORF) in subgroup IA strain Fny-CMV with the 2b ORFs of four subgroup IB strains, Cb7-CMV, PGs-CMV, Rad35-CMV and Na-CMV, generating FCb7(2b)-CMV, FPGs(2b)-CMV, FRad35(2b)-CMV and FNa(2b)-CMV, respectively" 08/01/2006 - "The introduction of defined mutations into open reading frames (ORF) or non-translated regions of the genome is important to study of the structure-function relationship of amino acid residues in proteins or that of sequence motifs at the genome level" 11/25/2005 - "In this study, we have analyzed an ORF from Corynebacterium glutamicum, which codes for a homologue of the Streptomyces coelicolor WhiB-family of proteins known to be involved in sporulation" Order ALL the reference details at left...
3.	Initiator Codon (Start Codon)IBA 01/30/2002 - "In each case, the entire ORF, with the exception of the first nucleotide of the start codon, was eliminated and replaced by the kanMX4 cassette" 04/15/2008 - "Occurrence of a mutation at the corresponding position of the CK/CH/LLN/98I start codon in the 3a gene led to the absence of ORF 3a in this virus, resulting in a novel genomic organization at the 3'-encoding regions: S-3b, 3c-M-5a, 5b-N" 08/01/2007 - "Thus, the overlapping region can direct the ribosome back onto the start codon of the second ORF while the upstream coding sequence of the M2-1 ORF determines the levels of coupled expression." 01/01/2007 - "Most notable are short ORFs located upstream of the start codon, which are known to regulate the translation of the main ORF in the transcript" 01/01/2007 - "A uORF can attenuate translation of the main ORF by interfering with translational reinitiation at the main start codon" Order ALL the reference details at left...
4.	Messenger RNA (mRNA)IBA 04/25/2006 - "Since exon 2 contains two upstream AUGs or open reading frames (uORFs), we hypothesized that these AUGs would inhibit the translation of the downstream hAT(1)R protein ORF harbored in exon 4. This study demonstrates that the inclusion of exon 2 in hAT(1)R mRNA transcripts dramatically reduces hAT(1)R protein levels (nine-fold) and significantly attenuates Ang II responsiveness ( approximately four-fold)" 01/01/1999 - "In the present study, the translational capacities of three mRNA species starting at the p97 promoter and containing the 880/2581, 880/2708 and 226/2708 splice junctions upstream of the E2 ORF were investigated" 01/01/1998 - "Analysis of transcripts and time-course studies demonstrated that the UL8 protein is translated from a delayed-early expressed 3.1 kb polyadenylated mRNA which initiates within the UL9 ORF." 02/01/1994 - "The LTR-ORF mRNA was expressed in activated B cells and activated mature CD8 but not CD4 T cells, consistent with previous functional studies assessing MLS activity in these cell types" 11/01/1993 - "mRNA studies revealed that ORF 5 formed a monocistronic operon and showed increased expression before onset of solventogenesis." Order ALL the reference details at left...
5.	TANDEMIBA 09/01/2008 - "This article describes an improved pooled open reading frame (ORF) expression technology (POET) that uses recombinational cloning and solution-based tandem mass spectrometry (MS/MS) to identify ORFs that yield high levels of soluble, purified protein when expressed in Escherichia coli" 07/01/2005 - "We demonstrated the efficacy of these methods by deleting an ORF, inserting the tandem affinity purification (TAP) tag, and replacing a wild-type allele with a mutant allele." 06/01/2007 - "They exist in three different domain configurations: a single ORF encoding one NrpR domain following an N-terminal helix-turn-helix (HTH); a single ORF encoding two NrpR domains fused in tandem following an N-terminal HTH; and two separate ORFs, one with a single domain following an N-terminal HTH and one with a single domain without a HTH" 01/01/2005 - "These collections consist of strains with an epitope tag integrated at the C-terminus of essentially every open reading frame (ORF), one with the tandem affinity purification (TAP) tag, and one with the green fluorescent protein (GFP) tag" 12/01/2001 - "DNA sequence analysis at this locus was extended and revealed a complete ORF for cbsT1 and no other ORFs in tandem" Order ALL the reference details at left...
6.	Complementary DNA (cDNA)IBA 05/01/1999 - "The ORF of this cDNA was subcloned into an expression vector, which relieved the unsaturated fatty acid (UFA) auxotrophy of a desaturase-deficient yeast strain following genetic transformation" 06/30/2008 - "In this study, we established new systematic protocols for the preparation of cDNA clones, conventionally termed open reading frame (ORF) clones, suitable for characterization of their gene products by adopting a restriction-enzyme-assisted cloning method using the Flexi cloning system" 11/01/2006 - "In the present study, a novel GmHSFA1 with an ORF of 1,533 bp (full-length cDNA sequence of 1,781 bp) was cloned from soybean genome via comparative genomic approach and RACE (rapid amplification of cDNA ends)" 11/01/2006 - "Using 5'-RACE with a specially designed primer based on the FDD study, a 1,401 bp cDNA clone was obtained containing a 1,311 bp open reading frame (ORF, GenBank accession number DQ306881)" 01/01/2000 - "In this study, the complete cDNA sequence of the rice (Oryza sativa cv Hinohikari) FDH gene, which contains an open reading frame (ORF) of 1128 bp, was determined" Order ALL the reference details at left...
7.	DNA (Deoxyribonucleic Acid)IBA 01/15/2002 - "Both percent survival and kinetics of cumulative deaths were improved using the combination DNA vaccine encoding ORF 6 and ORF 59" 01/01/2007 - "Preliminary studies using blood of eight gay men infected by human immunodeficiency virus-1 (HIV-1) revealed that, for the detection of HHV-8 DNA derived from open reading frame (ORF) 26 of the HHV-8 genome, this protocol provided substantially higher rates (100%) compared to one involving red blood cell (RBC) lysis (0%) and to another requiring double density gradient centrifugation (DDGC) of leukocytes (13%)" 10/01/2006 - "STUDY DESIGN: The open reading frames (ORF) 1, 6, 10, 21, 50, 54, and 62 were analyzed by sequencing of amplified DNA fragments" 09/25/2002 - "These results demonstrate that shotgun DNA-arrays and ORF-based DNA-arrays are appropriate tools to study physiology of microorganism." 10/15/1989 - "In the present study we show by in vitro synthesis of the td intron ORF product, that the protein possesses endonuclease activity and efficiently cleaves double-stranded DNA at or near the site of intron integration" Order ALL the reference details at left...
8.	RNA (Ribonucleic Acid)IBA 02/01/2008 - "These studies suggest that altering the fine structure of regulatory RNA or expression of a putative LAT ORF regulates the anti-apoptosis activity of LAT" 04/05/2005 - "Sequence analysis of the M RNA, thrips transmissibility assays, G(C) protein analysis, and transmission electron microscopic studies revealed that a specific nonsynonymous mutation (C1375A) in the G(N)/G(C) ORF of the M RNA resulted in the loss of thrips transmissibility without inhibition of virion assembly" 05/10/2003 - "Mutagenesis studies revealed that the production of this protein depends on the 5' X ORF ATG, suggesting that the 3.9-kb RNA is active in translation of the X ORF" 07/20/1999 - "As a prerequisite for further studies on the structure and function of this gene region, we mapped the transcripts encoded within MCMV HindIII-I. Probes for ORFs M140 and M141 hybridized to 5.4- and 7.0-kb RNA, respectively, which were transcribed with early kinetics and were 3' coterminal with HindIII-J ORF M139" 03/01/1993 - "Extending these in situ studies, we now report that VZV RNAs colinear with open reading frames (ORFs) 29 and 62 are demonstrable in non-neuronal cells; however, neither VZV RNA colinear with ORF 28 nor antisense RNAs of ORFs 29 and 62 are detected" Order ALL the reference details at left...
9.	Staphylococcal Protein A (A, Protein)IBA 11/01/1989 - "Nuclear extracts prepared from adenovirus-infected HeLa cells were cleared of E2F binding activity using the ORF 6/7 peptide-specific serum, but not the preimmune serum, suggesting that E2F and the E4 ORF 6/7 product form a protein-protein complex in solution" 04/01/2007 - "These studies suggest that a protein encoded by ORF-E has the potential to alter the physiology or metabolism of neuronal cell types, which may be important for long-term latency." 10/15/1996 - "The results of these studies indicate that ORF AV3 does not encode a protein" 08/01/2008 - "This gene has an open reading frame (ORF) of 249 bp in length, encoding a protein of 82 amino acid residues with the molecular mass of 8.1 kDa and theoretical pI of 4.71" 05/15/2008 - "Lessons learned from the accessory ORF-A protein of FIV." Order ALL the reference details at left...
10.	Glycoproteins (Glycoprotein)IBA 04/01/2003 - "The ORF 5 gene product of ILTV was previously described as a 60-kD glycoprotein (gp60), whereas multiple protein bands with apparent molecular masses of 85, 115, 160, and 200 kD were identified in the present study" 01/01/2006 - "A gene in UL/b' of HCMV, UL132 open reading frame (ORF), encodes glycoprotein (gpUL132) which is identified as a low-abundance structural component of HCMV" 12/01/2005 - "Sequencing of the genes flanking gG, Southern blot, PCR and western blot analyses of the mutant viruses demonstrated that the deletions were as expected, except for EHV4DeltagG mutants, which in addition to deletion of gG contained unexpected deletions in the adjacent down stream gene ORF 71 (glycoprotein 2)" 05/01/2005 - "Human cytomegalovirus (HCMV) ORF UL73 encodes the envelope glycoprotein gpUL73-gN, which shows seven genotypes (gN-1, gN-2, gN-3a, gN-3b, gN-4a, gN-4b, gN-4c)" 12/01/2004 - "The vcRNA ORF coded for viral glycoprotein (G1/G2) precursor of TCSV (128.46 kDa) and for glycoprotein precursor of GRSV (128.16 kDa)" Order ALL the reference details at left...

Therapies and Procedures

1.	Transplants (Transplant) 05/01/2006 - "Two giant orf lesions in a heart/lung transplant patient." 08/01/2001 - "The case is described of a renal transplant with a giant orf lesion, which continued growing instead of regressing spontaneously as is observed usually" 10/01/1989 - "The ORF graft implanted for 1 month was found crinkled in its mid-section and the external capsule was ruptured in the graft implanted for 6 month, without crinkling" 07/01/1998 - "DNA obtained from three laboratory reference strains (U1102, R104 and St.W.) and from HHV-6 infected peripheral white blood cells of bone marrow transplant patients and blood donors was used to test the applicability of two different SSCP analysis systems for the identification of HHV-6 variants using amplicons derived by PCR from the two genomic regions described above (U11 [pp100], U67 [13R-ORF])" 10/01/1989 - "At 6 month, the Mitrathane grafts were occluded by a thick thrombus originating from the anastomoses, while the ORF graft showed infiltration of collagen through the polyurethane fibrillar structure of the wall with an endothelial-like lining covering the flow surface in the vicinity of both anastomoses." Order ALL the reference details at left...
2.	Lasers (Laser) 03/01/2004 - "The proteomic analysis allowed matrix-assisted laser desorption/ionization-time of flight mass spectrometry-assisted identification of 86 protein spots which represent the product of 30 individual open reading frames (ORF)" 08/01/2007 - "By matrix-assisted laser desorption/ionization-time of flight analysis of the purified enzyme, ORF PA1029 was identified as a coding gene, gapor, in the sequenced genome of Pyrobaculum aerophilum" 04/01/1996 - "MATERIALS AND METHODS: Patients with either occlusion orf > 50% diameter stenosis less than 3 cm in length in the superficial femoral artery, and with two or three calf vessel run-off were eligible and randomised to receive either balloon angioplasty alone or with laser assistance" Order ALL the reference details at left...
3.	Kidney Transplantation 01/01/1999 - "A 48-year-old patient under immunosuppressive therapy for renal transplantation had contagious ecthyma which relapsed after excision" 02/01/1998 - "Parapoxvirus Orf in kidney transplantation." Order ALL the reference details at left...
4.	Heterologous Transplantation (Xenotransplantation) 10/01/2000 - "The BARF1 ORF was found to be transcribed and translated in >85% of our NPC biopsies, with high p31 protein level detected in several NPC patient biopsies as well as in NPC-derived xenografts" 07/01/2005 - "Four single nucleotide polymorphisms (G11A, G615C, G684A, T726G) in the ORF of the porcine PRNP gene were found, and the G-->C nucleotide substitution resulted in a serine to asparaginate amino acid substitution at codon 4. We conclude that pigs raised under specific pathogen-free conditions, with the exclusion of rendered mammalian material for at least two generations, will have little risk of being infected with a TSE, and even less possibility of transmitting prion disease to humans through xenotransplantation." Order ALL the reference details at left...
5.	Transplantation (Transplant Recipients) 01/01/1999 - "Hot spot mutations in morphological transforming region II (ORF 79) of cytomegalovirus strains causing disease from bone marrow transplant recipients." 11/05/1998 - "METHODS: Using an enzyme-linked immunosorbent assay with the recombinant HHV-8 protein orf 65.2, we analyzed serum samples from 220 renal-transplant recipients for the presence of antibodies to HHV-8 on the day of transplantation and one year later" Order ALL the reference details at left...

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