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Eclampsia

Onset of HYPERREFLEXIA; SEIZURES; or COMA in a previously diagnosed pre-eclamptic patient (PRE-ECLAMPSIA).
Also Known As:
Eclampsias
Networked: 1506 relevant articles (67 outcomes, 142 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pre-Eclampsia (Preeclampsia)
2. Seizures (Seizure)
3. Hypertension (High Blood Pressure)
4. HELLP Syndrome
5. Premature Obstetric Labor (Premature Labor)

Experts

1. Duley, Lelia: 13 articles (01/2015 - 06/2002)
2. Duley, L: 11 articles (01/2006 - 01/2000)
3. Moodley, J: 9 articles (02/2012 - 02/2000)
4. Magee, Laura A: 8 articles (11/2015 - 01/2004)
5. von Dadelszen, Peter: 8 articles (11/2015 - 01/2011)
6. Sibai, Baha M: 8 articles (05/2009 - 02/2003)
7. Vigil-De Gracia, Paulino: 6 articles (06/2015 - 11/2002)
8. Bhutta, Zulfiqar A: 5 articles (01/2015 - 01/2009)
9. Gülmezoglu, A M: 5 articles (03/2014 - 01/2002)
10. Cipolla, Marilyn J: 5 articles (01/2014 - 02/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Eclampsia:
1. MagnesiumIBA
10/01/2010 - "Simulation training is superior to traditional lecture alone for teaching crucial skills for the optimal management of both eclampsia and magnesium toxicity, 2 life-threatening obstetric emergencies."
01/01/2010 - "Six (11,444 women) compared magnesium sulphate with placebo or no anticonvulsant: magnesium sulphate more than a halved the risk of eclampsia (risk ratio (RR) 0.41, 95% confidence interval (CI) 0.29 to 0.58; number needed to treat for an additional beneficial outcome (NNTB) 100, 95% CI 50 to 100), with a non-significant reduction in maternal death (RR 0.54, 95% CI 0.26 to 1.10) but no clear difference in serious maternal morbidity (RR 1.08, 95% CI 0.89 to 1.32). "
09/01/2013 - "The purpose of this study was to determine whether a shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in controlling fits in eclampsia Between January and June 2011, 98 eclamptic mothers presenting at the labour ward of the University of Maiduguri Teaching Hospital were randomised to receive either the standard Pritchard regimen of magnesium sulphate or a shortened postpartum course in which only two doses of intramuscular magnesium sulphate is given four hours apart. "
09/01/2013 - "The shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in the management of eclampsia."
05/01/2011 - "In a randomised control study, we evaluated the efficacy of intravenous low-dose magnesium sulphate for the management of eclampsia. "
2. Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric
3. Phenytoin (Dilantin)FDA LinkGeneric
4. CalciumIBA
5. Diazepam (Valium)FDA LinkGeneric
6. EnzymesIBA
7. Hydralazine (Apresoline)FDA LinkGeneric
8. Fibrinogen (Factor I)FDA Link
9. LipidsIBA
10. Anticonvulsants (Antiepileptic Drugs)IBA

Therapies and Procedures

1. Prenatal Care
2. Cesarean Section (Caesarean Section)
3. Blood Transfusion (Blood Transfusions)
4. Critical Care
5. Curettage