|3.||Hypertension (High Blood Pressure)
|5.||Premature Obstetric Labor (Premature Labor)
|1.||Duley, Lelia: 13 articles (01/2015 - 06/2002)|
|2.||Duley, L: 11 articles (01/2006 - 01/2000)|
|3.||Moodley, J: 9 articles (02/2012 - 02/2000)|
|4.||Magee, Laura A: 8 articles (11/2015 - 01/2004)|
|5.||von Dadelszen, Peter: 8 articles (11/2015 - 01/2011)|
|6.||Sibai, Baha M: 8 articles (05/2009 - 02/2003)|
|7.||Vigil-De Gracia, Paulino: 6 articles (06/2015 - 11/2002)|
|8.||Bhutta, Zulfiqar A: 5 articles (01/2015 - 01/2009)|
|9.||Gülmezoglu, A M: 5 articles (03/2014 - 01/2002)|
|10.||Cipolla, Marilyn J: 5 articles (01/2014 - 02/2005)|
10/01/2010 - "Simulation training is superior to traditional lecture alone for teaching crucial skills for the optimal management of both eclampsia and magnesium toxicity, 2 life-threatening obstetric emergencies."
01/01/2010 - "Six (11,444 women) compared magnesium sulphate with placebo or no anticonvulsant: magnesium sulphate more than a halved the risk of eclampsia (risk ratio (RR) 0.41, 95% confidence interval (CI) 0.29 to 0.58; number needed to treat for an additional beneficial outcome (NNTB) 100, 95% CI 50 to 100), with a non-significant reduction in maternal death (RR 0.54, 95% CI 0.26 to 1.10) but no clear difference in serious maternal morbidity (RR 1.08, 95% CI 0.89 to 1.32). "
09/01/2013 - "The purpose of this study was to determine whether a shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in controlling fits in eclampsia Between January and June 2011, 98 eclamptic mothers presenting at the labour ward of the University of Maiduguri Teaching Hospital were randomised to receive either the standard Pritchard regimen of magnesium sulphate or a shortened postpartum course in which only two doses of intramuscular magnesium sulphate is given four hours apart. "
09/01/2013 - "The shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in the management of eclampsia."
05/01/2011 - "In a randomised control study, we evaluated the efficacy of intravenous low-dose magnesium sulphate for the management of eclampsia. "
|2.||Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric
07/01/2010 - "Despite the presence of high-quality evidence that magnesium sulfate is safe and effective at preventing and treating eclampsia, its use is extremely limited in many low-income countries. "
12/01/2001 - "Magnesium sulfate (MgSO4) is widely used for the treatment of eclampsia. "
02/01/1999 - "The data show that it is as effective as magnesium sulfate in preventing eclampsia, with less maternal and fetal side effects. "
03/01/2002 - "Magnesium sulfate therapy has been demonstrated to be both safe and effective in preventing neurological complications in obstetrical patients with eclampsia. "
04/01/1997 - "The results of this study are in support of a recent randomized trial on the efficacy of magnesium sulfate as a prophylactic agent against eclampsia. "
|3.||Phenytoin (Dilantin)FDA LinkGeneric
09/01/2002 - "The aim was to evaluate the changing trends in patients of eclampsia and to assess the efficacy of dilantin in its treatment. "
03/01/1997 - "Efficacy of phenytoin in eclampsia."
09/01/2002 - "Dilantin as anticonvulsant in eclampsia."
07/27/1995 - "Anticonvulsant prophylaxis with phenytoin for eclampsia has been recommended, but there are virtually no data to support its efficacy. "
11/01/1992 - "To investigate the efficacy of phenytoin in relation to total and free serum levels in patients with severe pre-eclampsia and eclampsia. "
08/01/1983 - "Results of the study support an association between calcium intake and development of eclampsia."
08/01/1983 - "In this study, the eclampsia incidence and calcium intake for three countries, Guatemala (low eclampsia incidence, high calcium intake); Cali, Colombia (high eclampsia incidence, low calcium intake); and the USA (low eclampsia incidence, high calcium intake) have been compared. "
03/04/1983 - "Epidemiologic and animal studies have suggested an inverse relationship between calcium intake and BP. Furthermore, calcium intake seems to be inversely correlated with the incidence of eclampsia in pregnancy. "
07/15/2000 - "In addition, some dogs with eclampsia may have low ionized calcium concentrations and not manifest typical clinical signs."
02/27/1992 - "Correction: platelet calcium metabolism in the prediction of eclampsia."
|5.||Diazepam (Valium)FDA LinkGeneric
01/01/2012 - "The study found a remarkable reduction in case fatality rate due to eclampsia in those who received MgSO4 therapy with minimal increase in costs when compared to diazepam therapy. "
01/01/2012 - "Prior to February 2008, diazepam was widely used for the management of eclampsia in Kano State (within northern Nigeria) with case fatality rate being over 20%. "
01/01/2012 - "Across Nigeria, diazepam is routinely used for the management of eclampsia. "
10/01/2011 - "Eclampsia occurred only in a member of the diazepam group but there were no maternal deaths. "
01/01/2004 - "Approximately one-third of obstetricians and family doctors use diazepam to treat eclampsia. "
01/01/1998 - "Platelets from eclampsia patients have reduced membrane microviscosity and lower activities of the signalling enzymes."
04/01/1992 - "Lack of significant changes in liver enzymes and in hemoconcentration in PIH and eclampsia indicate that liver damage and altered hemodynamics only play a partial role in causing hyperferritinemia. "
01/01/2016 - "There were no significant difference between the three groups as regards the incidence of eclampsia, elevated liver enzymes and low platelets syndrome, maternal ICU admission and; however The incidence of flushing was significantly higher in group III than group II and I (24 [30%] versus 12 [15%] versus 4 [5%]; p < 0.001) respectively. "
08/01/2015 - "In our multivariate model, African-American race [adjusted odds ratio (aOR)=1.9; 95% confidence interval (CI)=1.7-2.2], Hispanic ethnicity (aOR=1.5; 95% CI=1.2-1.8), other race (aOR=1.4; 95% CI=1.1-1.9), and haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome or eclampsia (aOR=2.8; 95% CI=2.2-3.5) were independently associated with receiving general anaesthesia for preterm Caesarean delivery. "
01/01/2015 - "Clinical data were collected to assess risk factors and the presence of severe complications, such as eclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome. "
|7.||Hydralazine (Apresoline)FDA LinkGeneric
08/01/1998 - "Hydralazine is the drug of choice for patients with eclampsia. "
04/01/1959 - "Routine use of intramuscular apresoline for the prevention of eclampsia."
01/01/1954 - "Prevention of an experimental eclampsia-like syndrome by Apresoline."
11/01/1953 - "Apresoline (l-hydrazinophthalazine) in the experimental eclampsia-like syndrome and related aspects of water metabolism."
07/01/1982 - "Although many institutions consider hydralazine the antihypertensive agent of choice in pre-eclampsia/eclampsia, there have been no comparative studies to document that hydralazine is the safest or most efficacious agent and only one human study evaluated its effects on maternal blood pressure, fetal heart rate, growth retardation, and uterine activity. "
|8.||Fibrinogen (Factor I)FDA Link
01/01/2006 - "Serum fibrinogen concentrations >450 mg/dL seem to be protective for eclampsia. "
01/01/2006 - "An initial diastolic blood pressure >or=120 mm Hg, blood leukocyte count >16,000/microL, and serum fibrinogen value <450 mg/dL were associated with a 25.4-, 7.1-, and 26.6-fold increased risk of eclampsia, respectively. "
05/15/1978 - "Studies on plasma fibrinogen level in pre-eclampsia and eclampsia."
03/01/1984 - "Fibrinogen proteolysis and platelet alpha-granule release in preeclampsia/eclampsia."
05/15/1978 - "The plasma fibrinogen value increased by about 70% and 145% in pre-eclampsia and eclampsia, respectively. "
11/01/2013 - "Serum lipids were found significantly higher thus early assessment may be helpful in prevention of complications in the eclampsia patients."
06/01/1961 - "Serum lipids in preeclampsia-eclampsia."
06/01/2004 - "The objective of this study in Gombe was to compare the levels of serum lipids and homocysteine in healthy pregnant women and women with preeclampsia/eclampsia in Nigeria. "
06/01/2004 - "Previous studies have produced contradictory findings regarding total homocysteine (tHcy) levels in women with preeclampsia/eclampsia and there is little information about the relationship between particular serum lipids and tHcy. "
04/01/2006 - "The terms preeclampsia, eclampsia, pregnancy-induced hypertension or toxemia were combined with dyslipidemia, hyperlipidemia, hypertriglyceridemia, lipids, cholesterol, triglycerides (TG) or lipoprotein. "
|10.||Anticonvulsants (Antiepileptic Drugs)IBA
06/01/1997 - "Comparative study of different anticonvulsants in eclampsia."
05/01/1996 - "Anticonvulsants in eclampsia: is this the final answer?"
08/19/1995 - "Anticonvulsants for eclampsia."
08/19/1995 - "Anticonvulsants for eclampsia."
08/19/1995 - "Anticonvulsants for eclampsia."
07/01/2006 - "Improvement in the quality and quantity of prenatal care should help reduce the incidence of eclampsia."
10/01/1989 - "Determinants aside from prenatal care that are responsible for maternal death from eclampsia are analyzed in this study. "
01/01/2013 - "Inadequate prenatal care among teenagers was a risk factor of eclampsia (12.6, 2.6 to 62.6), UTI (5.8, 1.7 to 19.7) and adverse neonatal outcomes. "
04/01/2004 - "This risk increases in the presence of eclampsia, particularly in neglected cases who have not sought prenatal care."
08/01/2003 - "To decrease the adverse outcome associated with eclampsia a community-based approach is needed to improve community health education, socioeconomic status and prenatal care. "
|2.||Cesarean Section (Caesarean Section)
11/01/2010 - "The use of the charts has resulted in improved monitoring of women with eclampsia and may have contributed to the reduction in the planned prelabour caesarean section rate from 87% to 33%, as more women underwent induction of labour after stabilisation (P = 0.020). "
08/01/2011 - "Ante partum eclampsia predominated (64%) and incidence of caesarean section was 22.25%.The overall case fatality rate was 6.05% and eclampsia contributed 27.85% of all maternal deaths during the last two years of the study period. "
01/01/2015 - "The clinical case presented deals with a 35 year-old pregnant woman whose history of eclampsia was observed after a cesarean section. "
10/01/2014 - "Ninety-nine cases of eclampsia were reviewed, of which 87 had Caesarean section. "
03/01/2012 - "Primary diagnosis was eclampsia, and for that reason she underwent cesarean section. "
|3.||Blood Transfusion (Blood Transfusions)
01/01/2013 - "Severe acute maternal morbidity (admission to an intensive care unit, eclampsia, blood transfusion of four or more packed cells, and other serious events), postpartum haemorrhage, and manual removal of placenta. "
06/01/2012 - "Maternal mortality ratio, with distribution of specific obstetric causes, and severe acute maternal morbidity, which included: eclampsia, surgery and blood transfusion for obstetric haemorrhage, and intensive-care unit admission. "
01/29/1949 - "Postpartum haemorrhage following eclampsia; treated by blood-transfusion."
05/01/2015 - "The main outcome was MNM, pragmatically defined as intensive care unit admission, eclampsia, hysterectomy, or blood transfusion. "
07/01/2013 - "According to a pragmatic definition, any woman reporting eclampsia, hysterectomy, blood transfusion, or admission to the intensive care unit during her pregnancy/childbirth was considered a near-miss case. "
10/01/2014 - "Eclampsia is still associated with high maternal and perinatal and perinatal morbidity and mortality, especially in resource poor countries with limited access to perinatal and critical care facilities. "
06/01/2013 - "We sought to investigate the concurrence of posterior reversible encephalopathy syndrome (PRES) with eclampsia and to describe the obstetric, radiological, and critical care correlates. "
12/01/2012 - "All patients obstetrical patients admitted to Critical Care Units of Seine-Maritime for eclampsia over a period of 7 years (2002-2008) were included. "
07/01/2012 - "We sought to investigate the concurrence of PRES with eclampsia and to describe the associated obstetric, radiologic and critical care correlates. "
04/01/2008 - "To assess the proportion of eclampsia among patients admitted to the critical care unit (CCU) with an acute neurological emergency in the peripartum period, and careful clinical, laboratory, and radiological evaluation of non-eclampsia cases responsible for such presentation. "
04/01/2007 - "The purpose of this study was describe two patients with rapid recovery of refractory late postpartum eclampsia (LPPE) following uterine curettage, and to evaluate the literature about supportive evidence for such a management in LPPE. "
04/01/2007 - "Late postpartum eclampsia: report of two cases managed by uterine curettage and review of the literature."
01/01/1969 - "[Place of uterine curettage in postpartum eclampsia]."
11/01/1964 - "[UTERINE CURETTAGE IN THE TREATMENT OF POSTPARTUM ECLAMPSIA]."
11/15/1962 - "Postpartum eclampsia treated by curettage."