|3.||Echinococcosis (Hydatid Cysts)
|1.||Ito, Akira: 26 articles (12/2015 - 09/2002)|
|2.||Wen, Hao: 24 articles (05/2015 - 01/2006)|
|3.||Craig, Philip S: 22 articles (05/2015 - 12/2002)|
|4.||McManus, Donald P: 21 articles (02/2015 - 01/2003)|
|5.||Sako, Yasuhito: 17 articles (12/2012 - 11/2002)|
|6.||Nakao, Minoru: 16 articles (12/2012 - 11/2002)|
|7.||Vuitton, Dominique A: 14 articles (05/2015 - 11/2002)|
|8.||Zhang, Wenbao: 14 articles (02/2015 - 01/2003)|
|9.||Xiao, Ning: 12 articles (01/2013 - 11/2002)|
|10.||Siracusano, A: 12 articles (03/2011 - 11/2000)|
|1.||Albendazole (Albenza)FDA Link
01/07/2015 - "Radical surgery with pre- and post-operative administration of albendazole is the best treatment option for liver hydatid cysts due to low recurrence and complication rates."
09/01/1992 - "We report a 33-year-old woman who was harboring multiple cerebral hydatid cysts and who was treated successfully with albendazole. "
09/01/1996 - "Albendazole in this study has proved to be effective in decreasing the viability of liver hydatid cysts when given for 3 weeks preoperatively."
03/01/2005 - "Dual albendazole treatment is effective in the prevention of recurrences and/or secondary hydatidosis."
01/01/2000 - "Our results support that perioperative albendazole treatment is effective in the prevention of secondary hydatidosis."
01/01/2012 - "Improved serodiagnosis of cystic echinococcosis using the new recombinant 2B2t antigen."
11/01/1997 - "All the hydatidosis patients responded positively by LPA to either crude or purified echinococcal antigens: 95% of them responded to either crude HCF, or a mixture of antigens A plus B and 83% to antigen B alone. "
09/01/1989 - "Efficacy of EIA with intact (IA) and fractionated (FA) antigens on 34 lung echinococcosis patients' sera and 42 control sera samples has been evaluated. "
01/01/1977 - "None of the sera from 22 patients suffering from illnesses other than hydatidosis or of the sera from 34 apparently normal individuals gave positive results with CIEP when either HHF or SHF was used as the source of antigen. "
01/01/2015 - "The study revealed that 72 (5.03%) out of 1,429 subjects asymptomatic for hydatidosis were seropositve to E.granulosus antigen by ELISA. "
|3.||Mebendazole (Vermin)FDA Link
01/01/1983 - "High oral doses of mebendazole have been only partly effective in the treatment of patients with alveolar or cystic echinococcosis, possibly due to an inadequate plasma concentration of the drug in some patients. "
01/01/1981 - "High oral doses of mebendazole have been only partly effective in the treatment of patients with alveolar or cystic echinococcosis. "
03/01/1981 - "Mebendazole has proved effective in the treatment of secondary echinococcosis. "
12/01/1985 - "Mebendazole was administered to 22 patients, 17 of whom had developing or cured hydatid cysts, and to 5 volunteers. "
10/01/1986 - "This study was undertaken to evaluate the prophylactic effect of mebendazole in experimental peritoneal hydatidosis. "
|4.||Praziquantel (Biltricide)FDA Link
12/01/2005 - "To assess the epidemiological efficacy of type SRP III slow-released praziquantel-medicated bars for dogs in the prevention and control of cystic echinococcosis in man and livestock, praziquantel-medicated bars were implanted subcutaneously in over 90% of dogs in villages in north Xinjiang, China, where cystic echinococcosis is highly endemic. "
12/01/2005 - "These results demonstrated not only that the slow released praziquantel-medicated bars efficiently blocked reinfection in dogs at least for 2 years, but also the measure was effective in preventing transmission of cystic echinococcosis to both man and livestock."
12/01/2005 - "Epidemiological evaluations of the efficacy of slow-released praziquantel-medicated bars for dogs in the prevention and control of cystic echinococcosis in man and animals."
07/01/2015 - "Cost-utility analysis revealed that dosing dogs with praziquantel (a cestocide) at six week intervals to control cystic echinococcosis is not currently cost-effective at a threshold of $20,000-100,000 per Quality Adjusted Life Year (QALY) gained, even in a health region with the highest incidence rate in Canada ($666,978-755,051 per QALY gained). "
05/01/2015 - "Regular praziquantel dosing of owned dogs in remote and semi-nomadic communities such as those in Hobukesar County is logistically very difficult and additional measures should be considered to reduce canine echinococcosis."
01/01/2012 - "In the present study, anti- Echinococcus antibodies were investigated by ELISA in patient's serum samples, which were routinely delivered to the Medical Microbiology Laboratory of Gazi University Faculty of Medicine due to suspected hydatid cyst. "
01/01/2012 - "To further investigate the epidemiology of echinococcosis in Greece a study was designed to determine the seroprevalence of Echinococcus granulosus antibodies in the population of Thessaly, Central Greece. "
05/01/2007 - "The aim of this study was to investigate anti-E granulosus antibodies by ELISA test as a complementary laboratory method in the diagnosis of human echinococcosis. "
01/01/2005 - "The aim of this study was to analyze the anti-Echinococcus antibodies in garbage men in Malatya who are regarded as high risk-group with regard to hydatid cysts. "
01/01/2016 - "In conclusion, our results suggest that antibodies - either natural or induced - play a role in the susceptibility degree to murine secondary cystic echinococcosis. "
|6.||Immunoglobulin G (IgG)IBA
04/01/2005 - "To determine the efficacy of immunoprecipitation (DD5), enzyme immunoanalysis (ELISA-IgG), and immunoelectrotransference or Western blot (WB) in patients with liver echinococcosis (LE) used separately, in parallel and in series. "
10/01/2000 - "This study shows the usefulness of the commercially available Echinococcus Western Blot IgG for the serological confirmation of human echinococcosis."
06/01/2000 - "The aim of the study is to evaluate the IgG subclasses for the diagnosis and follow-up of hydatidosis disease. "
04/01/2015 - "The IgG1 antibody shows the highest detection sensitivity by HCF, thus having potential value in diagnosis of cystic echinococcosis."
04/01/2015 - "ELISA was used to measure IgG and its subclasses IgG1, IgG2, and IgG4 specific for Echinococcus granulosus HCF, in the sera of 37 cystic echinococcosis (CE) patients and 29 healthy subjects in Huan County, Gansu Province. "
01/01/2015 - "The patient was started on perioperative benzimidazole therapy with resection of the hydatid cyst. "
01/01/2012 - "Cystic echinococcosis (CE) of the liver can be treated with ultrasound-guided puncture, aspiration, injection, and re-aspiration (PAIR), with surgery and with benzimidazole derivatives. "
05/01/2006 - "After the initially treatment with benzimidazole the curative surgery had been conducted and histological examination confirmed the liver echinococcosis diagnosis. "
02/01/2003 - "Benzimidazole treatment of cystic echinococcosis."
04/01/1995 - "These results suggest that a 5-day preoperative benzimidazole therapy either combined or not with a monthly postoperative course according to the viability of the protoscoleces at the time of operation, may erase the risk of recurrence after surgical treatment of the liver hydatidosis."
01/01/2000 - "Albendazole sulfoxide injection as a scolecidal agent in the percutaneous treatment of cystic echinococcosis seems to be effective in this animal model. "
10/01/2013 - "In vivo evaluation of the efficacy of albendazole sulfoxide and albendazole sulfoxide loaded solid lipid nanoparticles against hydatid cyst."
01/01/2015 - "granulosus, as well as the in vitro synergic therapeutic effects observed in presence of Met plus albendazole sulfoxide (ABZSO), suggest the importance of carrying out chemoprophylactic and clinical efficacy studies combining Met with conventional anti-echinococcal agents to test the potential use of this drug in hydatidosis therapy. "
01/01/1988 - "[Study of the distribution of albendazole sulfoxide by liquid chromatography in plasma and cyst fluid in hydatidosis]."
09/01/2011 - "These effects were compared with those of albendazole sulfoxide (800 µg/ml), a commonly used treatment drug for hydatidosis. "
10/01/2015 - "Chemoprophylactic and therapeutic efficacy of thymol in murine cystic echinococcosis."
10/01/2015 - "Thymol demonstrated efficacy against experimental murine cystic echinococcosis. "
02/01/1955 - "[General study of thymol therapy of hydatid cyst; method of Cuervo of Salamanca]."
03/01/2013 - "Could thymol have effectiveness on scolices and germinal layer of hydatid cysts?"
06/01/1956 - "[Medical treatment of hydatid cyst by injections of iodized thymol; Cuervo's method]."
|10.||Ivermectin (Mectizan)FDA Link
04/01/2002 - "Percutaneous treatment of cystic echinococcosis with ivermectin as a scolicidal agent seems to be effective in this animal model."
04/01/2002 - "In this experimental study, the effectiveness of intracystic injection of ivermectin was studied as a new approach of percutaneous treatment of cystic echinococcosis. "
02/01/1996 - "The effect of ivermectin on the hydatid cysts of Echinococcus granulosus was studied in vivo. "
02/01/1996 - "The effects of ivermectin on the hydatid cyst of Echinococcus granulosus after direct injection at laparotomy."
06/01/2002 - "The efficacy of a combination of ivermectin (IVM) and albendazole (ABZ) used as a chemoprophylactic treatment and as treatment of secondary hydatidosis is described for the first time. "
|1.||Drug Therapy (Chemotherapy)
01/01/2009 - "Is primary chemotherapy effective in large hydatid cyst of liver?"
06/01/2006 - "A serious public health problem caused by echinococcosis was evident in southern NHAR, typified by: a long diagnostic history for both AE and CE (7.5 years) compared with a shorter treatment history (4.7 years); a significant mortality rate (39%) caused by AE in one surveyed village, where patients had no previous access to treatment; family aggregation of CE and AE cases; a high proportion of both AE (62.5%) and CE (58%) in females; a high rate of recurrent surgery (30%) for CE demonstrated by surgical records; and frequent symptomatic recurrences (51%) because of discontinuous or sporadic access to chemotherapy for AE. The disease burden for both human AE and CE is thus very severe among these rural communities in NHAR, and this study provides the first attempt to determine the costs of morbidity and surgical intervention of human CE and AE cases both at the hospital and community level in this setting. "
07/01/2000 - "With regard to the studies' findings on cases of spinal hydatid cysts, the authors found that administration of chemotherapeutic drugs was the only statistically significant parameter (t = 3.78, p < 0.05), with the rate of chemotherapy higher in the cooperative study. "
07/01/2000 - "The two statistically significant findings of that study were expanded use of chemotherapy in the management of hydatidosis, and a higher rate of extraneural involvement in the disease. "
09/01/1997 - "We performed this study in 134 patients with hydatidosis: 17 patients with pre and post surgery treatment, 50 patients with post surgery treatment and 67 patients with chemotherapy only. "
02/01/2004 - "This method is simple and effective for obliteration of extremely large residual cavities after cystectomy for liver hydatidosis. "
09/01/2010 - "According to our experiences, transthoracic approach in lung hydatidosis, external drainage, and cystectomy in liver hydatidosis is safe and effective choices in surgical treatment."
01/01/2014 - "Efficacy of diffusion-weighted magnetic resonance imaging in follow-up patients treated with open partial cystectomy of liver hydatid cysts."
08/01/2014 - "The aim of this study was to compare postoperative outcome and long-term results after management of liver hydatid cysts (LHC) by subadventitial cystectomy (SC) and resection of the protruding dome (RPD) in two tertiary liver surgery centers. "
04/01/2014 - "This study evaluated omentoplasty versus partial cystectomy with drainage in surgical management of hydatid cysts of the liver in endemic area (Yemen). "
01/01/2008 - "The study was designed to determine comparatively the prognostic value of immunoblotting and ELISA in the serological follow-up of young cystic echinococcosis (CE) patients exhibiting either a cured or a progredient (non-cured) course of disease after treatment. "
04/01/2009 - "The objective of this study was to determine the values of different antigenic fractions of sheep hydatid cyst fluid in the follow-up of CE patients after treatment. "
07/01/2015 - "Eggs were infectious after heat exposure at 65 °C for up to 120 min, however, no echinococcosis developed after treatment of the eggs at 65 °C for 180 min or at 70, 75 and 80 °C for 7.5, 15 or 30 min."
01/01/1986 - "Osseous hydatidosis is a very uncommon disease which often recurs after treatment. "
10/01/2005 - "The main aims were to evaluate the effect of each drug on the hydatid cysts, to follow the changes in cyst morphology during and after treatment, and to determine how quickly each drug produced the first, detectable, degenerative changes in the cysts. "
08/01/2015 - "Spleen hydatidosis treated by hemi-splenectomy: A low-morbidity, cost-effective management by a recently improved surgical technique."
08/01/2015 - "Partial splenectomy for hydatidosis is effective and safe. "
08/01/2015 - "Demographic, clinical and surgical data were collected of four consecutive patients undergoing partial (or hemi-) splenectomy using an original, recently improved technique as a treatment for polar splenic hydatid cyst. "
12/01/2014 - "This study evaluated two surgical procedures, total splenectomy and spleen-preserving surgery, for the treatment of spleen cystic echinococcosis (CE). "
11/01/2010 - "The aim of this study was to outline the advantages of robotic partial splenectomy as a treatment for splenic hydatid cysts. "
09/01/2005 - "The purpose of the present study was to investigate the effects of the intracystic injections of alcohol and albendazole solutions on the hydatid cysts and hepatobiliary system of rabbits. "
02/01/1988 - "For the last 25 years, antisera for testing P1 in man have been obtained by i.v. injections in goats using hydatid cyst fluid from livers of pigs infected by Echinococcus granulosus. "
06/01/1956 - "[Medical treatment of hydatid cyst by injections of iodized thymol; Cuervo's method]."
12/02/1955 - "[Treatment of hydatid cysts with injections of iodized thymol (Cuervo's method)]."
02/01/1955 - "[Cuervo method in medical therapy of hydatid cysts; a case of hydatid cyst of the psoas apparently cured by injections of iodized thymol]."