|2.||Dysmenorrhea (Menstrual Pain)
|1.||Zhu, Jiang: 14 articles (01/2015 - 06/2010)|
|2.||Liu, Pei: 9 articles (01/2015 - 01/2011)|
|3.||Harel, Zeev: 7 articles (10/2012 - 01/2002)|
|4.||Ma, Liang-Xiao: 6 articles (01/2015 - 10/2010)|
|5.||Guo, Jianming: 6 articles (01/2015 - 04/2010)|
|6.||Gao, Shu-Zhong: 6 articles (01/2015 - 10/2010)|
|7.||Liu, Cun-Zhi: 6 articles (06/2014 - 05/2008)|
|8.||Guo, Sun-Wei: 6 articles (02/2014 - 01/2008)|
|9.||Tang, Yuping: 6 articles (01/2013 - 04/2010)|
|10.||Liang, Fanrong: 5 articles (08/2015 - 01/2013)|
|1.||Naproxen (Naprosyn)FDA LinkGeneric
02/01/2002 - "The patient had a pattern of naproxen use during menses for dysmenorrhea. "
05/01/1985 - "Also, adolescents who reported more severe dysmenorrhea symptoms following three months of naproxen therapy had significantly lower self-concepts than adolescents who reported less symptoms following treatment."
05/01/1985 - "Factors influencing adolescents' responses to regimens of naproxen for dysmenorrhea."
01/01/1983 - "Naproxen in the treatment of OC-resistant primary dysmenorrhea. "
05/01/1980 - "26 women aged 15-45 with severe, primary dysmenorrhea were treated with naproxen (NAPROSYN, SYNTEX) and placebo during 2 x 2 consecutive menstrual cycles in a randomized, double-blind crossover study. "
|2.||Ibuprofen (Motrin)FDA LinkGeneric
09/01/1979 - "The study shows that in severe primary dysmenorrhea there is increased release of PG in the menstrual fluid; this can be effectively suppressed with ibuprofen, which provides excellent relief from the symptoms of dysmenorrhea. "
06/01/1998 - "We conclude that the prophylactic administration of ibuprofen is an effective treatment for selected women experiencing severe and disabling primary dysmenorrhea."
01/01/2011 - "The purpose of this study was to compare the efficacy of fish oil and Ibuprofen on the treatment of primary dysmenorrhea. "
03/01/2001 - "To compare the efficacy of topically applied heat for menstrual pain with oral ibuprofen and placebo treatment. "
03/01/1981 - "We found that ibuprofen therapy reduced menstrual prostaglandin release and relieved dysmenorrhea but that placebo therapy did not. "
11/01/1978 - "Sixty-four women with primary dysmenorrhea participated in a double-blind, parallel trial of maproxen sodium versus placebo during three menstrual cycles. "
06/01/1956 - "Clearance of radioactive sodium from the cervix in women with normal menstrual cycles, primary dysmenorrhea, and nonorganic pelvic pain, and in postmenopausal individuals."
04/15/1977 - "The efficacy of naproxen sodium (naproxen-Na) in dysmenorrhea has been established in two independent double-blind (placebo-controlled) studies. "
05/01/1985 - "The efficacy of different regimens of naproxen sodium for relief of dysmenorrhea in female adolescents was compared and the effect of other social/psychologic factors on the response to treatment tested. "
01/01/1989 - "In conclusion, this study indicates that naproxen sodium is a useful and safe drug in the treatment of premenstrual and menstrual pain related symptoms."
10/01/2005 - "Oral contraceptives are effective for dysmenorrhea."
01/01/1979 - "When oral contraceptives became available it was found that they represented an effective remedy for dysmenorrhea. "
01/01/1983 - "The efficacy of oral contraceptives (OC) in the treatment of primary dysmenorrhea in controlled studies varies from 50 to 80%. "
10/01/2006 - "We recruited adolescents to study oral contraceptives versus placebo for dysmenorrhea. "
07/01/2005 - "Oral contraceptives for dysmenorrhea in adolescent girls: a randomized trial."
|5.||Diclofenac (SR 38)FDA LinkGeneric
09/01/1998 - "Diclofenac was effective in revealing menstrual pain both with and without the IUD, and reduced the PI in the absence of an IUD [pre-treatment 2.39 (0.62) versus post-treatment 2.12 (0.45); P < 0.001], but had no effect when the IUD was present [pre-treatment 2.13 (0.43) versus post-treatment 2.10 (0.41)]. "
09/01/1990 - "Diclofenac may not be as effective for dysmenorrhea. "
08/01/2009 - "Administration of diclofenac potassium compared to placebo not only attenuated the women's menstrual pain (P < 0.05), but also increased sleep efficiency (P < 0.05) and percentage of REM sleep (P < 0.01), decreased percentage of stage 1 sleep (P < 0.05) and number of sleep stage changes per hour of sleep (P < 0.05), and improved subjective ratings of sleep quality and morning vigilance (P < 0.05). "
02/01/2009 - "We assessed the efficacy of diclofenac potassium, a nonsteroidal anti-inflammatory drug, in alleviating menstrual pain and restoring exercise performance to that measured in the late-follicular phase of the menstrual cycle. "
01/01/2006 - "Clinical evaluation to assess the safety and efficacy of coded herbal medicine "Dysmo-off" versus allopathic medicine "Diclofenac sodium" for the treatment of primary dysmenorrhea."
|6.||Mefenamic Acid (Pontal)FDA Link
01/01/1980 - "It is concluded that the mefenamic acid is safe and effective in most patients for the relief of primary dysmenorrhea and represents a rational short-term therapy for this syndrome."
02/01/2003 - "The essence of fennel can be used as a safe and effective herbal drug for primary dysmenorrhea, however, it may have a lower potency than mefenamic acid in the dosages used for this study."
11/01/2014 - "Comparative evaluation of the efficacy of herbal drugs (fennelin and vitagnus) and mefenamic acid in the treatment of primary dysmenorrhea."
11/01/2014 - "The aim of this study was to compare the effects of herbal products (fennelin and vitagnus) and mefenamic acid in the treatment of primary dysmenorrhea. "
04/01/2014 - "The aim of this study was to assess the effect of Dill compared to mefenamic acid on primary dysmenorrhea. "
|7.||Levonorgestrel (Plan B)FDA LinkGeneric
09/01/1991 - " Levonorgestrel has also been associated with significant reduction in menstrual pain. "
04/01/1982 - "Patients suffering from dysmenorrhea experienced relief from this symptom after insertion of a levonorgestrel-IUD. "
11/01/2014 - "Compared with the Mirena group, scores for dysmenorrhea integral increased and scores for SDBSS decreased in the CM treatment group (P < 0.01, P < 0.05). "
03/01/2012 - "Two patients in levonorgestrel-releasing intrauterine system group (7.4%) and nine in the expectant management group (39.1%) had recurrent dysmenorrhea within 1 year postoperatively (P=.014). "
01/01/2012 - "However, statistically, Mirena reduced dysmenorrhea faster and earlier compared to cupper IUD (p<0.003). "
|8.||Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
05/20/1988 - "Cumulative data of clinical trials indicate that with the effective NSAIDs, 80 percent of patients with significant primary dysmenorrhea can be adequately relieved. "
05/20/1988 - " NSAIDs Relief can be obtained in 80-85% of patients studied, with NSAIDs shown to be clinically effective against primary dysmenorrhea. "
05/20/1988 - "With the official approval and availability of several effective NSAIDs for the specific treatment of primary dysmenorrhea in the United States, women who have primary dysmenorrhea have been greatly relieved and their productivity increased. "
08/01/2013 - "Management of primary dysmenorrhea is primarily based on a treatment by NSAIDS. "
10/01/2012 - "Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) is the preferred initial treatment for dysmenorrhea in nonsexually active adolescents/young adults. "
09/01/2008 - "The objective of the present investigation was to study differences in plasma concentrations of reproductive hormones in women with primary dysmenorrhea vs. healthy controls. "
06/01/2006 - "The purpose of the present study was to examine the associations among hormone concentrations, self-rated Tanner staging and dysmenorrhea, and to determine whether various psychosocial factors modulate these relationships. "
11/01/2014 - "Association of antimüllerian hormone levels with menstrual-cycle type and dysmenorrhea in young asymptomatic women."
01/01/2014 - "Menstrual symptoms such as dysmenorrhea usually occur during the hormone-free interval in oral contraceptive users. "
01/01/2014 - "Evaluations included changes in total dysmenorrhea score, visual analog scale for dysmenorrhea, severity of symptoms, hormone levels, endometrial thickness, and safety outcomes. "
|10.||Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
01/01/1979 - "The capacity of the technique is exemplified with results achieved in a study of the effect of prostaglandin synthetase inhibitors and beta-receptor stimulating agents during dysmenorrhea."
04/01/2011 - "Current therapies for dysmenorrhea include prostaglandin synthetase inhibitors and herbal remedies. "
01/01/1999 - "Ten plants used by traditional healers for menstrual pains were assayed for cyclooxygenase inhibitory activity. "
01/01/1999 - "Inhibition of cyclooxygenase and hence of the prostaglandin biosynthetic pathway may lead to relief of menstrual pain. "
01/01/1999 - "Plants used by Southern African traditional healers for the treatment of menstrual pains were screened for prostaglandin-synthesis inhibitors and the ability to reduce isolated uterine muscle contraction using the cyclooxygenase and in vitro uterine bioassays respectively. "
01/01/2013 - "Acupressure at SP6 may be effective in the relief from primary dysmenorrhea. "
11/01/2010 - "To examine whether applying a simple acupressure protocol to the Taichong point is effective in relieving dysmenorrhea. "
06/01/2002 - "An acupressure device is an effective and safe nonpharmacologic strategy for the treatment of primary dysmenorrhea. "
01/01/2013 - "To evaluate the efficacy of acupressure in the treatment of primary dysmenorrhea based on randomized controlled trials (RCTs), we searched MEDLINE, the Chinese Biomedical Database (CBM), and the Cochrane Central Register of Controlled Trials (CENTRAL) databases from inception until March 2012. "
11/01/2010 - "A randomized clinical trial of the efficacy of applying a simple acupressure protocol to the Taichong point in relieving dysmenorrhea."
03/01/2014 - "Topical heat, exercise, and nutritional supplementation may be beneficial in patients who have dysmenorrhea; however, there is not enough evidence to support the use of yoga, acupuncture, or massage. "
12/01/2012 - "This study showed that massage was effective in reducing dysmenorrhea. "
12/01/2015 - "Based on the present findings, it seems that massage therapy and isometric exercises were effective in reducing some symptoms of dysmenorrhea."
12/01/2015 - "We sought to compare the effects of massage and isometric exercises on primary dysmenorrhea. "
12/01/2015 - "Comparison of the Effect of Massage Therapy and Isometric Exercises on Primary Dysmenorrhea: A Randomized Controlled Clinical Trial."
|3.||Contraception (Birth Control)
03/01/1980 - " If a woman wants contraception concomitantly with seeking relief from severe dysmenorrhea, and if following a history and a physical she is found to be free of any pelvic pathology or contraindications for the oral contraceptive (OC), then OCs may be regarded as appropriate. "
08/01/1979 - "In all, 40 per cent of patients reported an increase in menstrual blood loss ad 26 per cent of patients an increase in menstrual pain, and this could not be attributed entirely to stopping oral contraception; 42 per cent of patients reported improvement in their sex lives after sterilisation, while 6.6 per cent reported deterioration mainly due to lack of libido. "
07/01/2013 - "The influence of intrauterine contraception on the prevalence and severity of dysmenorrhea: a longitudinal population study."
12/01/2015 - "Menstrual pain severity and oral contraception use was obtained from questionnaires at 20 and 22-year follow-ups. "
10/01/2015 - "Both methods identically demonstrated pronounced effect of combined hormonal contraception on decline in sexual desire and painful menstruation. "
|4.||Transcutaneous Electric Nerve Stimulation (TENS)
05/01/2007 - "Both transcutaneous electrical nerve stimulation and interferential current appear to be effective in primary dysmenorrhea. "
03/27/1996 - "[TENS is effective in painful menstruation]."
01/01/1994 - "We conclude that TENS is an effective and safe non-pharmacological means for the treatment of primary dysmenorrhea. "
01/01/1994 - "Transcutaneous electrical nerve stimulation (TENS) as a relief for dysmenorrhea."
10/01/2009 - "Conclusion. This result supports that women in our country who suffer from primary dysmenorrhea could benefit by using TENS, which is consistent with the previous studies. "
08/01/2011 - "Our data suggest that a far infrared-emitting sericite belt with a hot pack might be used as an effective and safe non-pharmacologic treatment option for women with primary dysmenorrhea, with a prolonged effect after treatment."
10/25/2011 - "Dysmenorrhea disappeared after treatment in 13 cases, relieved markedly in 2 and no improvement in 1. The endometrial ectopic growth was not observed after treatment. "
02/01/2006 - "Clinical study showed that in the treated group and the control group, after treatment, dysmenorrhea score were 2.40 +/- 1.85 and 3.47 +/- 2.03, the menoxenia score 1.67 +/- 2.04 and 3.73 +/- 1.72 (P < 0.05), and the pregnancy rate 63.2% and 23.5% respectively, the difference between them was significant (all P < 0.05). "
11/01/2015 - "203 of the 224 patients who showed varying degrees of dysmenorrhea before treatment had the symptom scores decreased significantly after treatment (P<0.001). "
08/01/2015 - "Clinical outcomes, including symptomatic changes of dysmenorrhea and HMB, uterine volume change, complications, and the overall success rate were evaluated in each patient after treatment with the LNG-IUS. "