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Dysgerminoma

A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)
Also Known As:
Disgerminomas; Dysgerminomas; Disgerminoma
Networked: 315 relevant articles (21 outcomes, 21 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Seminoma
3. Teratoma (Teratoid Tumor)
4. Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
5. Endodermal Sinus Tumor (Endodermal Sinus Tumors)

Experts

1. Cheng, Liang: 6 articles (05/2011 - 10/2004)
2. Schneider, Dominik T: 5 articles (01/2013 - 01/2006)
3. Roth, Lawrence M: 5 articles (05/2011 - 10/2004)
4. Zheng, Wenxin: 5 articles (05/2011 - 10/2004)
5. Looijenga, Leendert H J: 4 articles (01/2012 - 02/2002)
6. Karim, Fadi W Abdul: 4 articles (08/2006 - 10/2004)
7. Stoop, Hans: 3 articles (01/2012 - 02/2002)
8. Oosterhuis, J Wolter: 3 articles (01/2012 - 02/2002)
9. Jones, Timothy D: 3 articles (08/2006 - 11/2005)
10. Michael, Helen: 3 articles (04/2006 - 10/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dysgerminoma:
1. Cisplatin (Platino)FDA LinkGeneric
2. Cyclophosphamide (Cytoxan)FDA LinkGeneric
3. Keratins (Keratin)IBA
4. alpha-Fetoproteins (AFP)IBA
5. PlatinumIBA
6. Periodic AcidIBA
7. Hematoxylin (Haematoxylon)IBA
8. Eosine Yellowish-(YS) (Eosin)IBA
9. PyronineIBA
10. Methyl Green (Green, Light)IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Radiotherapy
3. Ovariectomy (Oophorectomy)
4. Hysterectomy
5. Combination Drug Therapy (Combination Chemotherapy)