Dysarthria (Spastic Dysarthria)

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273 relevant articles (20 outcomes, 18 trials/studies) found for this Disease

Description: Disorders of speech articulation caused by imperfect coordination of pharynx, larynx, tongue, or face muscles. This may result from CRANIAL NERVE DISEASES; NEUROMUSCULAR DISEASES; CEREBELLAR DISEASES; BASAL GANGLIA DISEASES; BRAIN STEM diseases; or diseases of the corticobulbar tracts (see PYRAMIDAL TRACTS). The cortical language centers are intact in this condition. (From Adams et al., Principles of Neurology, 6th ed, p489)

Also Known As:

Spastic Dysarthria; Dysarthosis; Dysarthria, Flaccid; Dysarthria, Guttural; Dysarthria, Mixed; Dysarthria, Scanning; Dysarthria, Spastic; Dysarthoses; Dysarthrias; Dysarthrias, Flaccid; Dysarthrias, Guttural; Dysarthrias, Mixed; Dysarthrias, Scanning; Dysarthrias, Spastic; Flaccid Dysarthria; Flaccid Dysarthrias; Guttural Dysarthria; Guttural Dysarthrias; Mixed Dysarthria; Mixed Dysarthrias; Scanning Dysarthria; Scanning Dysarthrias; Spastic Dysarthrias

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3405

Neurologic Manifestations: 2874

Neurobehavioral Manifestations: 295

Communication Disorders: 83

Language Disorders: 73

Speech Disorders: 89

Articulation Disorders: 20

Dysarthria: 273

Signs and Symptoms Pathological Conditions

Signs and Symptoms

Neurologic Manifestations: 2874

Neurobehavioral Manifestations: 295

Communication Disorders: 83

Language Disorders: 73

Speech Disorders: 89

Articulation Disorders: 20

Dysarthria: 273

Related Diseases

1.	Paresis (Hemiparesis)
2.	Parkinson Disease (Parkinson's Disease)
3.	Ataxia (Dyssynergia)
4.	Deglutition Disorders (Dysphagia)
5.	Headache (Headaches)
166 Diseases and 209 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Hughes, T: 3 articles (01/2005 - 01/2001)
2.	Langhorne, P: 3 articles (01/2005 - 01/2001)
3.	Sellars, C: 3 articles (01/2005 - 01/2001)
4.	Playford, E D: 2 articles (01/2001 - 01/2001)
5.	Whurr, R: 2 articles (01/2001 - 01/2001)
6.	Deane, K H: 2 articles (01/2001 - 01/2001)
7.	Ben-Shlomo, Y: 2 articles (01/2001 - 01/2001)
8.	Clarke, C E: 2 articles (01/2001 - 01/2001)
9.	Dumas, Claude: 1 article (05/2007)
10.	Laffont, Isabelle: 1 article (05/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dysarthria:

1.	Cyclosporine (Ciclosporin)FDA LinkGeneric 06/01/1992 - "Immediate withdrawal of cyclosporine at the onset of a change in mental status or dysarthria and improvement in intra- and postoperative management may have contributed to the decreased incidence of neurological complications." 11/01/1998 - "Therefore, cyclosporine may cause central pontine myelinolysis, being dysarthria the first manifestation of neurotoxicity" 11/01/1998 - "Three liver transplant recipients treated with cyclosporine developed a reversible neurologic syndrome characterized by early dysarthria, which evolved to anarthria, and tetraparesis" 11/01/2002 - "In patients receiving cyclosporin and tacrolimus, headache, tremors, dysarthria, seizures and delirium are the most common disorders and are not always related to toxic drug concentrations or overdosage" 03/01/1997 - "He had been treated for Behçet uveitis using cyclosporine and colchicine during the past 5 years, and he acutely presented with fever and headache, followed left hemiparesis, dysarthria and dysphagia" Get all the results and reference details, order at left...
2.	Carbamazepine (Tegretol)FDA LinkGeneric 06/01/2001 - "The patient's complaints, including dysarthria, improved after carbamazepine treatment." 09/01/1990 - "We report a case of a patient who attained toxic carbamazepine serum concentrations (ranging from 18.2 to 21.5 micrograms/mL) two days after cardiothoracic surgery and an intraoperative myocardial infarction, and experienced lethargy, diplopia, dysarthria, diaphoresis, and horizontal and downgaze nystagmus" 11/01/2000 - "The neurologic signs and symptoms of carbamazepine and phenytoin toxicity, such as ataxia, dysarthria, and nystagmus, are well known" Get all the results and reference details, order at left...
3.	antineoplaston A10 (A 10)IBA 02/01/1993 - "The present communication concerns a 46 year old woman with a 10 year history of chronic progressive multiple sclerosis (MS) in whom external application of magnetic fields (MF) (7.5 picoTesla; 5 Hz) during a period of remission resulted in a rapid and dramatic improvement in symptoms including vision, cerebellar symptomatology (ataxia and dysarthria), mood, sleep, bowel and bladder functions as well as fatigue" 09/01/2002 - "As a differential diagnosis, we report a 10 year-old boy who had long episodes of abdominal pain accompanied by blurring of vision, vertigo, gait ataxia, dysarthria, acroparesthesias and vomiting" 06/01/1994 - "A 68 year old man with a 10 year history of apparently benign IgM kappa paraproteinaemia presented with dysarthria, left hemiparesis, and a sensory peripheral neuropathy" Get all the results and reference details, order at left...
4.	Intravenous Immunoglobulins (IVIG)FDA Link 09/01/2008 - "This is a report about an immunocompetent 4-year-old female child affected with acute encephalitis by parvovirus B19, documented by polymerase chain reaction performed on cerebrospinal fluid, who was treated with intravenous immunoglobulins and dexamethasone and who developed a cerebellar syndrome with ataxia, dysmetria, and dysarthria" 03/01/2000 - "Assuming intravenous immunoglobulins (IVIG) to also be effective in CPM, 0.4 g/kg body weight/d immunoglobulins were applied to a 48-year-old patient who developed CPM with double vision, dysarthria, dysphagia, and left-sided hemiparesis 3 weeks after spontaneous normalization of hyponatremia" Get all the results and reference details, order at left...
5.	Acetazolamide (Diamox)FDA LinkGeneric 01/01/1985 - "Clinical features: paroxysmal bouts of ataxia and dysarthria, nystagmus of permanent gaze, the dominant autosomal transmission, the benign nature of the affection and the remarkable efficacy of acetazolamide were typical of familial paroxysmal ataxia" 02/01/1995 - "Acetazolamide responsive hereditary paroxysmal cerebellar ataxia (APCA) is a rare autosomal dominant disorder characterized by attacks of cerebellar ataxia and dysarthria with normal or near normal neurologic function between attacks" Get all the results and reference details, order at left...
6.	Paroxetine (Paxil)FDA LinkGeneric 01/30/2007 - "The symptoms were initially regarded as further manifestations of her somatic symptoms of depression, and paroxetine was increased to 30 mg/day resulting in frequent clonus, increased shivering, serious dysarthria, ongoing impairment in visual acuity and agitation" 01/30/2007 - "Ten mg/day of paroxetine rechallenge provoked dysarthria, tremor and headache, but these symptoms improved again upon paroxetine discontinuation" Get all the results and reference details, order at left...
7.	DroxidopaIBA 01/01/1985 - "Marked improvement in frozen gait was observed in 1-2 weeks, and that of dysarthria in 2-3 weeks, after the initiation of L-threo-DOPS administration" 01/01/1985 - "Frozen gait and dysarthria were markedly alleviated by L-threo-DOPS administration, and the rigidity persisting under conventional medication was also relieved" Get all the results and reference details, order at left...
8.	Thyrotropin-Releasing Hormone (Prolactin Releasing Hormone)FDA Link 05/01/1991 - "Her neurological symptoms (drowsiness, emotional lability, dysarthria, dysphagia, and quadriparesis) were improved dramatically by treatment with thyrotropin-releasing hormone (TRH) and rehabilitation" Get all the results and reference details, order at left...
9.	Piracetam (Nootropil)IBA 11/01/1996 - "Piracetam also had positive benefits on gait ataxia and convulsions but not on dysarthria, and feeding and hand writing improved much more significantly" Get all the results and reference details, order at left...
10.	PapaverineIBA 01/01/1999 - "The patient was treated successfully with intra-arterial papaverine and achieved a nearly full recovery, with only mild dysarthria, by the time of the 7-month follow-up examination" Get all the results and reference details, order at left...
152 Drugs and Important Bio-Agents and 204 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Language Therapy (Language Training) 01/01/2005 - "OBJECTIVES: To determine the efficacy of speech and language therapy interventions for adults with dysarthria following non-progressive brain damage" 02/01/2002 - "OBJECTIVE: To determine the efficacy of speech and language therapy interventions for adults with dysarthria following nonprogressive brain damage" 01/01/2002 - "OBJECTIVES: To determine the efficacy of speech and language therapy interventions for adults with dysarthria following non-progressive brain damage" 01/01/2001 - "OBJECTIVES: To determine the efficacy of speech and language therapy interventions for adults with dysarthria following non-progressive brain damage" 12/15/2005 - "The study examines judgements of the cognitive status of speakers with acquired dysarthria made by health care professionals.METHODS AND PROCEDURES: Doctors, speech and language therapists and speech and language therapy students viewed videos of speakers with acquired dysarthria and of controls matched for age and gender who had acquired neurological deficits that did not affect their speech" Get all the results and reference details, order at left...
2.	Biofeedback (Psychology) (Biofeedback) 01/01/1999 - "The results of the study demonstrated that real-time continuous visual biofeedback techniques for modifying speech breathing patterns were not only effective, but superior to the traditional therapy techniques for modifying abnormal speech breathing patterns in a child with persistent dysarthria following severe TBI" 01/01/1994 - "An EMG biofeedback technique was developed for the treatment of dysarthria" 01/01/1994 - "EMG biofeedback in the treatment of dysarthria." 05/01/1985 - "A microcomputer-based wearable biofeedback device to improve transfer of treatment in parkinsonian dysarthria." 02/01/1984 - "EMG biofeedback in the modification of hypertonia in spastic dysarthria: case report." Get all the results and reference details, order at left...
3.	Transplantation (Transplant Recipients) 07/01/2008 - "Eight months following transplantation, he presented with progressive dysarthria, cognitive and visual decline" 05/01/1993 - "Dysarthria and cerebellar ataxia: late occurrence of severe neurotoxicity in a liver transplant recipient." 12/01/2004 - "Two weeks after transplantation, dysarthria and right hemiparesis began to resolve, and CT showed spontaneous resolution of the hematoma" 12/01/2004 - "Nine days before the scheduled transplantation, she developed dysarthria and right hemiparesis; computed tomography (CT) of the brain disclosed an acute hematoma in the left parietal lobe exceeding 3 cm in diameter" 11/01/1998 - "Three liver transplant recipients treated with cyclosporine developed a reversible neurologic syndrome characterized by early dysarthria, which evolved to anarthria, and tetraparesis" Get all the results and reference details, order at left...
4.	Occupational Therapy (Therapy, Occupational) 09/01/2002 - "We identified 16 physiotherapy randomised controlled trials (399 patients), two occupational therapy trials (84 patients), and five speech and language therapy for dysarthria trials (154 patients)" 01/01/1995 - "Moreover, symptoms do not respond equally to drug treatment, balance (with succeeding falls) and swallowing being special problems for anti-parkinsonian drug treatment, but also vegetative symptoms, dysarthria, motor skills etc. Apart from medication patients get relief also from adjuvant therapy like physiotherapy, occupational therapy, and speech therapy, which all can lead to improvement of quality of life" 12/01/2005 - "The multiplicity and progressiveness of the disabilities in ALS, highlights the need for a coordinated multidisciplinary rehabilitation program managing symptoms, respiratory care, dysphagia and nutrition, dysarthria and communication, physical and occupational therapy" 09/01/2005 - "INTERVENTIONS: Basic rehabilitative treatment that included physical therapy, occupational therapy and/or speech therapy for impairments such as hemiplegia, ataxia or dysarthria was administered for two weeks (control treatment)" Get all the results and reference details, order at left...
5.	Pallidotomy 08/01/2006 - "AE thought to be related to the STN DBS following pallidotomy included worse dysarthria (three) and worse balance (two)" 12/01/2000 - "The present study was designed to examine changes in vocal intensity following unilateral posteroventral pallidotomy (PVP) in a large sample of speakers with Parkinson's disease (PD) that exhibited a range of hypokinetic dysarthria" Get all the results and reference details, order at left...
40 Therapies and Procedures and 83 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Patient-Physician
Research Summary Report
on Dysarthria

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