Fonofos

11/15/2023 - "Compared to the reference group (never use, PRS < median), men with ever use of fonofos and PRS > median had elevated risks of total (OR 1.35 [1.06-1.73], p-interaction = 0.03) and aggressive (OR 1.49 [1.09-2.04], p-interaction = 0.19) prostate cancer. "
11/15/2023 - "We observed interaction between ever use of fonofos and the PRS in relation to total and aggressive prostate cancer risk. "
02/01/2012 - "Men carrying the variant A allele at ERCC1 rs2298881 exhibited increased prostate cancer risk with high versus no fonofos use [odds ratio (OR) 2.98; 95% confidence interval (CI) 1.65-5.39; P(interact) = 3.6 × 10(-4); FDR-adjusted P = 0.11]. "
12/01/2011 - "Our significant finding regarding fonofos is consistent with previous AHS findings of increased prostate cancer risk with fonofos exposure among those with a family history of prostate cancer. "
12/01/2011 - "Fonofos exposure was associated with a monotonic increase in prostate cancer risk among men with CT/TT genotypes for rs1983132 [odds ratios (95% confidence intervals) for low and high use compared with no use were 1.65 (0.91, 3.01) and 3.25 (1.78, 5.92), respectively], whereas fonofos was not associated with prostate cancer risk among men with the CC genotype. "

12/01/2006 - "Fonofos exposure and cancer incidence in the agricultural health study."
12/01/2006 - "This finding along with findings of associations between organophosphate pesticides and cancer more broadly led to this study of fonofos and risk of any cancers among 45,372 pesticide applicators enrolled in the AHS. "

07/01/1999 - "Pigeons kept individually under ad libitum feeding conditions in the laboratory do not suffer lethal poisoning because they develop a strong avoidance response to fonofos-treated seed, which restricts consumption to below lethal levels. "
07/01/1999 - "Effects of food restriction on food avoidance and risk of acute poisoning of captive feral pigeons from fonofos-treated seeds "
09/01/1982 - "An accidental poisoning (in 1977) of 28 Holstein cows occurred when approximately 0.9 kg of 25% active ingredient fonofos, O-ethyl S-phenyl ethylphosphonothiolothionate, was spilled onto bulk feed in a delivery truck. "
09/01/1982 - "Fonofos toxicosis in dairy cows: an accidental poisoning (1977)."
02/01/2002 - "The risk of acute poisoning by phorate and fonofos continued though the winter."

02/10/1990 - "A 32-year-old woman who had ingested 300 ml of a potent cholinesterase inhibitor insecticide (Fonofos) with suicidal intent became progressively comatose and finally suffered respiratory arrest. "