Dydrogesterone

A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit OVULATION.

Also Known As:

Networked: 223 relevant articles (36 outcomes, 59 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Schindler, Adolf E: 7 articles (08/2018 - 12/2009)
2.	Mueck, Alfred O: 6 articles (11/2020 - 10/2007)
3.	Raghupathy, Raj: 5 articles (01/2022 - 08/2005)
4.	Szekeres-Bartho, Julia: 5 articles (01/2022 - 04/2005)
5.	Clavel-Chapelon, Françoise: 4 articles (09/2014 - 01/2008)
6.	Fournier, Agnès: 4 articles (09/2014 - 01/2008)
7.	Bergeron, C: 4 articles (06/2010 - 08/2000)
8.	Rozenberg, Serge: 3 articles (12/2021 - 07/2010)
9.	Ruan, Xiangyan: 3 articles (11/2020 - 08/2018)
10.	Zhang, Wei: 3 articles (08/2020 - 01/2013)

Related Diseases

1.	Endometriosis 09/01/2023 - "Dydrogesterone combined with non-steroidal anti-inflammatory drugs is a safe and effective treatment for patients with endometriosis. " 10/01/2007 - "In conclusion, dydrogesterone is an effective and safe post-laparoscopic treatment for endometriosis." 01/01/2023 - "Dydrogesterone after laparoscopic surgery in patients with endometriosis stage III and IV improved the natural pregnancy rate." 01/01/2003 - "[Efficacy of duphaston treatment in women with endometriosis after reconstructive surgery]." 07/01/2022 - "To the best of our knowledge this is the first study showing the effects of dydrogesterone on sexual function in patients with endometriosis.What"
2.	Dysmenorrhea (Menstrual Pain) 01/01/2019 - "Dydrogesterone is efficacious, safe, and clinically beneficial in patients with dysmenorrhea, thereby indicating that dydrogesterone can be considered as a treatment option for patients with dysmenorrhea." 01/01/2019 - "Baseline of the total dysmenorrhea score was 4.61, which went down over time following the administration of dydrogesterone, and the decrease was statistically significant at and after 2nd cycle of menstruation. " 01/01/2019 - "We sought to evaluate the efficacy and safety of dydrogesterone in Japanese women with dysmenorrhea. " 01/01/2019 - "The efficacy and safety of dydrogesterone for treatment of dysmenorrhea: An open-label multicenter clinical study." 01/01/2016 - "Dydrogesterone therapy was effective in achieving MC regularization and reducing menstrual pain and anxiety, during both treatment and 6-month FU. "
3.	Spontaneous Abortion (Miscarriage) 06/01/2015 - "Although all the predictive and confounding factors could not be controlled for, the results of this systematic review show a significant reduction of 29% in the odds for miscarriage when dydrogesterone is compared to standard care indicating a real treatment effect. " 12/01/2012 - "Although all the predictive and confounding factors could not be controlled for, the results of this systematic review show a significant reduction of 47% in the odds for miscarriage when dydrogesterone is compared to standard care indicating a real treatment effect." 09/08/2023 - "In this study, our objective was to analyze the cervical and vaginal microbiomes during early pregnancy among three groups: women with healthy ongoing pregnancies, women undergoing dydrogesterone treatment, and those who experienced miscarriages. " 10/01/2005 - "Oral dydrogesterone treatment during the first trimester of pregnancy: the prevention of miscarriage study (PROMIS). " 09/08/2023 - "Cervical and Vaginal Microbiomes in Early Miscarriages and Ongoing Pregnancy with and without Dydrogesterone Usage."
4.	Threatened Abortion 01/01/2023 - "Studies were included if they were randomized controlled trials (RCTs) evaluating the effect of integrating Gushen Antai Pills and dydrogesterone in patients with threatened miscarriage, and reported the outcomes of interest. " 01/01/2016 - "A randomized double-blind controlled trial of the use of dydrogesterone in women with threatened miscarriage in the first trimester: study protocol for a randomized controlled trial." 12/01/2009 - "The aim of this study was to determine whether dydrogesterone helps to preserve pregnancy in women with threatened miscarriage. " 01/01/2023 - "This meta-analysis aimed to systematically evaluate the effectiveness and safety of Gushen Antai Pills combined with dydrogesterone in the treatment of threatened miscarriage. " 01/01/2023 - "Efficacy and safety of Gushen Antai Pills combined with dydrogesterone in the treatment of threatened miscarriage: a systematic review and meta-analysis."
5.	Habitual Abortion (Recurrent Miscarriage) 12/01/2005 - "In order to draw final conclusions as to the usefulness of dydrogesterone in women with a history of recurrent miscarriage, further controlled, blinded, randomised clinical trials are needed." 10/01/2005 - "A prospectively randomized, placebo-controlled study of 20 mg dydrogesterone per day during the first trimester of pregnancy in women aged between 18 and 38 and with a history of idiopathic recurrent miscarriage. " 10/01/2005 - "A planned study to test the hypothesis that dydrogesterone given during the first trimester of pregnancy can positively influence the immune system of women suffering from recurrent miscarriages and thereby lead to successful pregnancies. " 09/04/2023 - "Experts unanimously agreed on the efficacy and safety of dydrogesterone and its recommendation in guidelines for threatened and recurrent miscarriage. " 09/04/2023 - "Opinions varied on the preference for dydrogesterone in recurrent miscarriage treatment. "

Related Drugs and Biologics

1.	Estradiol (Delestrogen)
2.	Progesterone
3.	Progestins (Progestagens)
4.	Hormones (Hormone)
5.	Lipids
6.	Immunologic Factors (Immunomodulators)
7.	Medrogestone
8.	Glucose (Dextrose)
9.	Anti-Bacterial Agents (Antibiotics)
10.	Norgestrel (DL-Norgestrel)

Related Therapies and Procedures

1.	Therapeutics
2.	Hormone Replacement Therapy (Therapy, Hormone Replacement)
3.	Estrogen Replacement Therapy
4.	Pessaries
5.	Contraception (Birth Control)