Drug Administration Schedule

12/01/2021 - "The identification of optimal drug administration schedules to overcome the emergence of resistance that causes treatment failure is a major challenge in cancer research. "
01/01/2017 - "The identification of optimal drug administration schedules to battle the emergence of resistance is a major challenge in cancer research. "
08/01/2016 - "The simulation results show that the drug administration schedule could differentiate the damages against proliferation of normal and cancer cells. "
08/21/2014 - "Evolutionary theory has contributed to the understanding of the dynamics of resistance mutations in a cancer cell population, the risk of resistance pre-existing before the initiation of therapy, the composition of drug cocktails necessary to prevent the emergence of resistance, and optimum drug administration schedules for patient populations at risk of evolving acquired resistance. "
11/01/2009 - "Our methodology can be used to identify optimum drug administration schedules to avoid resistance conferred by one (epi)genetic alteration for any cancer and treatment type."

10/01/2007 - "To ascertain whether treatment of anemia in the critically ill with exogenous erythropoietin and iron might improve outcomes and to optimize drug administration schedules and dosage, further studies with sufficient statistical power and adequate follow-up are warranted."

12/01/1999 - "In phase II trials in patients with colorectal cancer that was recurrent or refractory to 5-Ruorouracil (5-FU)based front-line therapy, response rates of 14% to 22% and median survival times of 8 to 10 months have been consistently reported by groups from Japan, Europe, and the United States using avariety of drug administration schedules Two recently reported phase III trials comparing CPT-II against infusional 5-FU or best supportive care demonstrated that CPT-II confers a survival advantage over either of the two other approaches. "

10/01/2007 - "To ascertain whether treatment of anemia in the critically ill with exogenous erythropoietin and iron might improve outcomes and to optimize drug administration schedules and dosage, further studies with sufficient statistical power and adequate follow-up are warranted."

01/01/1988 - "[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; problems on standardization of the appropriate time for the withdrawal of anti-ulcer agents]."
01/01/1988 - "[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; administration of synergistic drugs for protective factors in peptic ulcer--criteria of drug selection according to clinical symptoms and administration methods]."
01/01/1988 - "[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; intermittent and long-term administration]."
01/01/1988 - "[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; combination therapy of inhibitors of attacking factors and synergistic drugs for protective factors in peptic ulcer--selection of drug combinations and clinical efficacy]."