Droperidol

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703 relevant articles (160 outcomes, 142 trials/studies) found for this Drug

Description: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)

Also Known As:

Dehidrobenzperidol; Droleptan; Inapsine; Janssen Brand of Droperidol; Kern Brand of Droperidol; Taylor Brand of Droperidol; Dehydrobenzperidol; 2H-Benzimidazol-2-one, 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydro-4-pyridinyl)-1,3-dihydro-

Relationship Network

Drug Context: Research Results

Organic Chemicals: 42

Heterocyclic Compounds: 25

2-Ring Heterocyclic Compounds

Benzimidazoles: 83

Droperidol: 703

Innovar: 68

Experts

1.	Tanaka, H: 5 articles (03/2001 - 01/2000)
2.	Fujii, Y: 5 articles (03/2001 - 01/2000)
3.	Gan, Tong J: 4 articles (11/2006 - 07/2002)
4.	Fujii, Yoshitaka: 3 articles (12/2003 - 09/2002)
5.	Peixoto Filho, A J: 2 articles (08/2006 - 10/2000)
6.	Peixoto, A J: 2 articles (08/2006 - 10/2000)
7.	Celich, M F: 2 articles (08/2006 - 10/2000)
8.	Horta, M L: 2 articles (06/2006 - 03/2000)
9.	Tanaka, Hiroyoshi: 2 articles (04/2003 - 09/2002)
10.	White, Paul F: 2 articles (11/2002 - 07/2002)

Related Diseases

1.	Postoperative Nausea and Vomiting (PONV) 01/01/1999 - "CONCLUSION: Prophylactic antiemetic therapy with droperidol 50 microg.kg(-1) (maximum dose, 2.5 mg) is highly effective for preventing PONV after LC." 09/01/1999 - "Treatment with droperidol was more effective when the baseline risk for PONV was higher than 25% for early PONV and 35% for late PONV. " 09/01/2005 - "All treatment groups, except droperidol during the postoperative 3-24 h, were effective for prevention of postoperative nausea and vomiting during the postoperative 0-24 h." 09/01/2001 - "The continuous epidural administration of droperidol is effective in prevention of postoperative nausea and vomiting and the effect lasts during its infusion with no side effects." 09/01/2000 - "Droperidol was effective for this purpose with incidence of PONV of 25% (P < 0.05). " Order ALL the reference details at left...
2.	Vomiting 05/01/1981 - "The results showed that the dose of droperidol used in this study was very effective in reducing vomiting in children 11 to 15 years of age. " 05/01/1995 - "There was a significant reduction in the incidence of vomiting in the recovery room (1.4% vs 9.2%, P < 0.005) and in the day ward (9.4% vs 18.3%, P < 0.05) in patients receiving droperidol. " 01/01/1992 - "Droperidol seems to be more effective in reducing severe vomiting. " 01/01/1992 - "Droperidol was more effective in reducing severe vomiting. " 09/01/2003 - "In controls, the incidence of vomiting was 24.4%; with droperidol 5 micro g, it was 23.2% (NNT compared with control, 82 [7 to -8.5]); with 15 micro g, it was 22.0% (NNT, 41 [6.5 to -9.6]); and with 50 micro g, it was 12% (NNT, 8.1 [4.2-142]). " Order ALL the reference details at left...
3.	Nausea 09/01/2009 - "RESULTS: Over 24 h, nausea was reduced from 42.9% in the control to 32.0% in the droperidol group, corresponding to a relative risk (RR) of 0.75 (95% CI from 0.66 to 0.84). " 10/01/2003 - "Droperidol trended toward a greater mean reduction of nausea than placebo at 5 minutes (20 versus 4, p=0.077). " 09/01/2003 - "In controls, the incidence of nausea was 48.8%; with droperidol 5 micro g, it was 42.7% (NNT compared with control, 16 [95% confidence interval, 4.7 to -11]); with 15 micro g, it was 32.9% (NNT, 6.3 [3.3-100]); and with 50 micro g, it was 21.7% (NNT, 3.7 [2.4 to 7.6]). " 11/01/2000 - "Small-dose droperidol effectively reduces nausea in a general surgical adult patient population." 08/01/1999 - "CONCLUSION: Despite the prophylactic administration of 0.5 mg droperidol i.v., patients undergoing ambulatory laparoscopic surgery reported a high incidence of nausea after discharge. " Order ALL the reference details at left...
4.	Strabismus (Squint) 02/01/2004 - "STUDY OBJECTIVE: To compare the frequency of postoperative emetic symptoms and side effects in pediatric strabismus surgery using four doses of droperidol. " 02/01/2004 - "Effects of droperidol dosage on postoperative emetic symptoms following pediatric strabismus surgery." 06/01/1990 - "Droperidol-induced extrapyramidal symptoms in an adolescent following strabismus surgery." 12/01/1983 - "The antiemetic effect of droperidol following outpatient strabismus surgery in children." 03/01/1981 - "Low doses (0.05 mg/kg) of intravenously administered droperidol were given intraoperatively to randomly assigned pediatric strabismus patients in a controlled double-masked paradigm. " Order ALL the reference details at left...
5.	Migraine Disorders (Migraine) 06/01/2003 - "The butyrophenone neuroleptic droperidol is very effective in aborting acute migraine attacks. " 07/01/1999 - "Droperidol 2.5 mg intramuscular may be a safe and effective therapy for the ED management of acute migraine headache. " 06/01/1997 - "Droperidol is effective and safe in treating status migrainosus or refractory migraine. " 01/01/2002 - "The objective of the study was to further assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache. " 01/01/2002 - "A randomized clinical trial to assess the efficacy of intramuscular droperidol for the treatment of acute migraine headache." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Ondansetron (Zofran)
2.	Metoclopramide (Reglan)
3.	Granisetron (Kytril)
4.	Dexamethasone (Maxidex)
5.	Propofol (Diprivan)
6.	Antiemetics
7.	Morphine (MS Contin)
8.	dolasetron mesylate (dolasetron)
9.	Fentanyl (Sublimaze)
10.	Cisplatin (Platino)

Related Therapies and Procedures

1.	Laparoscopic Cholecystectomy
2.	General Anesthesia
3.	Tonsillectomy
4.	Analgesia
5.	Gynecologic Surgical Procedures (Gynecologic Surgery)

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