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Doxepin (Mareen)

A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
Also Known As:
Mareen; Zonalon; Aponal; Sinequan; Sinquan; Apo-Doxepin; Deptran; Desidox; Doneurin; Doxepia; Doxepin Hydrochloride; Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5); Doxepin beta; Doxepin-RPh; Espadox; Novo-Doxepin; Prudoxin; Quitaxon; Xepin; Apo Doxepin; ApoDoxepin; Doxepin RPh; Hydrochloride, Doxepin; Novo Doxepin; 1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl-
Networked: 363 relevant articles (49 outcomes, 77 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Rogowski, Roberta: 7 articles (02/2012 - 11/2007)
2. Roth, Thomas: 6 articles (02/2012 - 11/2007)
3. Lankford, Alan: 5 articles (02/2012 - 11/2007)
4. Ludington, Elizabeth: 5 articles (02/2012 - 10/2010)
5. Mika, Joanna: 4 articles (03/2021 - 01/2013)
6. Jochelson, Philip: 4 articles (10/2011 - 10/2010)
7. Epstein, Joel B: 4 articles (03/2008 - 01/2003)
8. Oien, Hal: 4 articles (03/2008 - 01/2003)
9. Truelove, Edmond L: 4 articles (03/2008 - 01/2003)
10. Zu, Hengbing: 3 articles (02/2020 - 10/2015)

Related Diseases

1. Sleep Initiation and Maintenance Disorders (Insomnia)
2. Pruritus (Itching)
3. Pain (Aches)
4. Neuralgia (Stump Neuralgia)
5. Atopic Dermatitis (Atopic Eczema)

Related Drugs and Biologics

1. Amitriptyline (Elavil)
2. Tricyclic Antidepressive Agents (Tricyclic Antidepressants)
3. Venlafaxine Hydrochloride (Effexor)
4. Imipramine (Janimine)
5. Fluoxetine (Prozac)
6. Histamine Antagonists (Antihistamines)
7. Antidepressive Agents (Antidepressants)
8. Mustard Gas (Sulfur Mustard)
9. Doxepin (Mareen)
10. Nortriptyline (Aventyl)

Related Therapies and Procedures

1. Therapeutics
2. Radiotherapy
3. Renal Dialysis (Hemodialysis)
4. Hemoperfusion
5. Topical Administration