Doxepin (Mareen)

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230 relevant articles (25 outcomes, 43 trials/studies) found for this Drug

Description: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.

Also Known As:

Mareen; Zonalon; Aponal; Sinequan; Sinquan; Aliud Brand of Doxepin Hydrochloride; Alphapharm Brand of Doxepin Hydrochloride; Apo-Doxepin; Apotex Brand of Doxepin Hydrochloride; Azupharma Brand of Doxepin Hydrochloride; Bioglan Brand of Doxepin Hydrochloride; Deptran; Desidox; Desitin Brand of Doxepin Hydrochloride; Doneurin; Doxepia; Doxepin AL; Doxepin AZU; Doxepin Holsten; Doxepin Hydrochloride; Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5); Doxepin Lindo; Doxepin Stada; Doxepin beta; Doxepin dura; Doxepin-RPh; Doxepin-TEVA; Doxepin-neuraxpharm; Doxepin-ratiopharm; Espadox; Healthpoint Brand of Doxepin Hydrochloride; Hexal Brand of Doxepin Hydrochloride; Holsten Brand of Doxepin Hydrochloride; Krewel Brand of Doxepin Hydrochloride; Lindopharm Brand of Doxepin Hydrochloride; Merck dura Brand of Doxepin Hydrochloride; Nepalm Brand of Doxepin Hydrochloride; Novo-Doxepin; Novopharm Brand of Doxepin Hydrochloride; Pfizer Brand of Doxepin Hydrochloride; Prudoxin; Quitaxon; Roche Brand of Doxepin Hydrochloride; Rodleben Brand of Doxepin Hydrochloride; Stadapharm Brand of Doxepin Hydrochloride; Temmler Brand of Doxepin Hydrochloride; Teva Brand of Doxepin Hydrochloride; Xepin; betapharm Brand of Doxepin Hydrochloride; biomo Brand of Doxepin Hydrochloride; doxepin-biomo; esparma Brand of Doxepin Hydrochloride; neuraxpharm Brand of Doxepin Hydrochloride; ratiopharm Brand of Doxepin Hydrochloride; Apo Doxepin; ApoDoxepin; Doxepin RPh; Doxepin TEVA; Doxepin neuraxpharm; Doxepin ratiopharm; Hydrochloride, Doxepin; Lindo, Doxepin; Novo Doxepin; Stada, Doxepin; doxepin biomo; doxepinbiomo; 1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)-ylidene-N,N-dimethyl-

Relationship Network

Drug Context: Research Results

Organic Chemicals: 40

Heterocyclic Compounds: 23

3-Ring Heterocyclic Compounds

Experts

1.	Epstein, Joshua D: 3 articles (03/2008 - 08/2006)
2.	Oien, Hal: 3 articles (03/2008 - 08/2006)
3.	Epstein, Matthew S: 3 articles (03/2008 - 08/2006)
4.	Epstein, Joel B: 3 articles (03/2008 - 08/2006)
5.	Truelove, Edmond L: 3 articles (03/2008 - 08/2006)
6.	McCleane, Gary: 2 articles (01/2004 - 01/2002)
7.	Rüther, E: 2 articles (12/2003 - 06/2001)
8.	Rodenbeck, A: 2 articles (12/2003 - 06/2001)
9.	Hajak, G: 2 articles (12/2003 - 06/2001)
10.	Cohrs, S: 2 articles (12/2003 - 06/2001)

Related Diseases

1.	Pain (Aches) 08/01/1982 - "The efficacy of doxepin compared with that of placebo was thus documented in several depressive and pain parameters, indicating that doxepin is a valuable treatment for patients with chronic pain and depression." 01/01/2003 - "The purpose of this study was to assess the anesthetic effect of doxepin oral rinse in normal subjects to identify the duration of effect and to contrast the anesthetic effect with reported pain relief in patients with oral mucosal lesions" 12/01/2001 - "The results of this single dose trial suggest that topical doxepin rinse has significant ability to provide clinically significant pain relief in patients with mucosal damage with an extended duration of effect." 03/01/1984 - "Doxepin's effects on chronic pain and depression: a controlled study." 03/01/2008 - "These results indicate that doxepin rinsing continues to produce reduced intensity of pain levels over a 1-week span of repeated dosing." Order ALL the reference details at left...
2.	Pruritus (Itching) 12/01/1995 - "RESULTS: Twenty-four hours after initiation of treatment, and continuing throughout the remainder of the study, patients treated with doxepin cream experienced significantly greater pruritus relief than did vehicle-treated patients as determined by all efficacy parameters (P < .002)" 10/01/1994 - "Pruritus severity scores demonstrated significantly greater improvement with topical doxepin at each study visit (p < 0.01)" 08/01/1999 - "Pruritus relief and lessening of pruritus severity were significantly greater with doxepin/TAC than doxepin alone" 10/01/1994 - "At each of three visits, the physician's global evaluation for relief of pruritus also showed significant improvement in the doxepin treatment group (p < 0.01)" 08/01/1999 - "CONCLUSION: Topically applied doxepin is safe and effective therapy for pruritus." Order ALL the reference details at left...
3.	Atopic Dermatitis (Atopic Eczema) 02/01/1999 - "The addition of topical doxepin to corticosteroid therapy: an improved treatment regimen for atopic dermatitis." 08/01/1999 - "METHODS: Twenty-four subjects with atopic dermatitis received either doxepin or doxepin/TAC cream 4 times daily for 7 days in a randomized, double-blind, controlled trial" 08/01/1999 - "Pharmacokinetics of doxepin in subjects with pruritic atopic dermatitis." 10/01/1994 - "CONCLUSION: Topical doxepin is effective in reducing pruritus in patients with atopic dermatitis" 10/01/1994 - "OBJECTIVE: The current study was undertaken to compare the efficacy and safety of topical 5% doxepin cream in relieving pruritus associated with atopic dermatitis" Order ALL the reference details at left...
4.	Depressive Disorder (Melancholia) 02/01/1978 - "Practically no support was found for the position that doxepin may be more beneficial for anxious-depressive syndromes" 06/01/1986 - "The efficacy of low doses (10 to 20 mg daily) of doxepin in the treatment of depressive disorders in elderly inpatients was assessed by a double-blind study in 24 patients" 03/01/1997 - "This randomized double-blind placebo-controlled study on doxepin is the first investigation of the effect of the switch from parenteral to oral administration on symptoms of endogenous depression" 03/01/1997 - "On the problems of switching from intravenous to oral administration in drug treatment of endogenous depression--a placebo-controlled double-blind trial with doxepin." 03/01/2007 - "A randomized controlled clinical trial comparing "guideline exposed" and "guideline naive" physicians in respect to dosage selection and treatment outcome with doxepin in depressive disorders." Order ALL the reference details at left...
5.	Urticaria (Hives) 11/01/1986 - "We conclude that doxepin is an effective agent for the treatment of chronic idiopathic urticaria." 11/01/1986 - "Efficacy of doxepin in the treatment of chronic idiopathic urticaria." 11/01/1986 - "Doxepin hydrochloride, a tricyclic antidepressant, was evaluated in a double-blind, placebo-controlled crossover trial for the treatment of chronic idiopathic urticaria in 16 adults" 01/01/1996 - "Based on the treatment of cold urticaria it has been suggested that doxepin, which has known H1- and H2-antagonistic effects, may in addition show specific anti-PAF activity" 01/01/1990 - "The combined H1, H2 and muscarinic blocking activities of doxepin may contribute towards explaining its clinical efficacy in the treatment of chronic urticaria." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Amitriptyline (Elavil)
2.	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)
3.	Imipramine (Janimine)
4.	Fluoxetine (Prozac)
5.	Doxepin (Mareen)
6.	Histamine H1 Antagonists (Antihistamines)
7.	Nortriptyline (Aventyl)
8.	Antidepressive Agents (Antidepressants)
9.	Piroxicam (Feldene)
10.	Hydroxyzine (Vistaril)

Related Therapies and Procedures

1.	Hemoperfusion
2.	Analgesia
3.	Microelectrodes
4.	Renal Dialysis (Hemodialysis)
5.	Electroacupuncture

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