Recombinant DNA (Recombinant DNA Research)

Biologically active DNA which has been formed by the in vitro joining of segments of DNA from different sources. It includes the recombination joint or edge of a heteroduplex region where two recombining DNA molecules are connected.

Also Known As:

Networked: 913 relevant articles (51 outcomes, 116 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Zhang, Xiaoyan: 4 articles (01/2019 - 12/2012)
2.	Sheng, Xiuzhen: 3 articles (01/2021 - 01/2019)
3.	Tang, Xiaoqian: 3 articles (01/2021 - 01/2019)
4.	Xing, Jing: 3 articles (01/2021 - 01/2019)
5.	Xu, Hongsen: 3 articles (01/2021 - 01/2019)
6.	Zhan, Wenbin: 3 articles (01/2021 - 01/2019)
7.	Xu, Jianqing: 3 articles (01/2019 - 05/2014)
8.	Tian, Yingfang: 3 articles (01/2018 - 01/2011)
9.	Valenta, Rudolf: 3 articles (02/2016 - 04/2011)
10.	Ander, Bradley P: 3 articles (08/2015 - 01/2011)

Related Diseases

1.	Neoplasms (Cancer) 11/30/2010 - "This study demonstrates how alternatively spliced genes can reliably be identified in a cancer data set. " 02/01/2001 - "However, the results of this study suggest that differential growth conditions within tumors could markedly affect the expression of recombinant DNA under control of both inducible and constitutive promoters. " 01/01/1993 - "Cancer Research Campaign operation manual for control recommendations for products derived from recombinant DNA technology prepared for investigational administration to patients with cancer in phase I trials." 05/08/1986 - "These studies provide the basis for prenatal and postnatal prediction of susceptibility to inherited cancer using arbitrary recombinant DNA markers. " 03/01/2023 - "Only in the later 1990s, the genetic engineering and the recombinant DNA techniques that allowed the generation of potent, specific and safe OVs and a better understanding of cancer cells renewed the interest in virotherapy. "
2.	Infections 01/01/2020 - "To study the effect of α-MMC on plant viral defence and how α-MMC increases plant resistance to viruses, recombinant DNA and transgenic technologies were employed to investigate the role of α-MMC in Nicotiana benthamiana resistance to tobacco mosaic virus (TMV) infection. " 12/01/2019 - "In the present study, a recombinant DNA plasmid based on the expression of Hsp33 gene was constructed and intramuscularly administrated to flounder to elucidate whether it induces immune response and prevents the infection of Vibrio anguillarum in flounder model. " 01/01/2021 - "Using six different time points, we were able to identify the presence of differentially spliced genes at 6, 9, 12, 24, 48 and 72 hours post-infection. " 12/20/2019 - "Here, we provide a detailed general protocol for infection, propagation, purification, and titering of Chlamydia trachomatis serovar L2 with additional notes specifically pertaining to mutants or recombinant DNA carrying clones." 01/01/2019 - "Differential expression analysis of the alternatively spliced genes in healthy and smut-infected sugarcane revealed 896 AS events modulated at different stages of infection. "
3.	Hepatitis B 04/01/1985 - "Recombinant DNA techniques in the study of hepatitis B virus infection." 10/01/1992 - "Recombinant DNA hepatitis B vaccination in teenagers: effect of a booster at 5 1/2 years." 05/01/1990 - "Neuralgic amyotrophy following recombinant DNA hepatitis B vaccination." 10/01/1988 - "Recombinant DNA related to hepatitis B and human immunodeficiency viruses in mononuclear cells of patients with AIDS." 09/01/2004 - "[Application of exponent curve model to study the hepatitis B DNA recombinant yeast derived vaccine antibody levels]."
4.	Hemophilia A (Haemophilia) 04/01/1997 - "A prospective, open-label multicenter investigation has been conducted to compare pharmacokinetic parameters of recombinant DNA-derived FVIII (rFVIII) and plasma-derived FVIII concentrate (pdFVIII) and to assess safety and efficacy of long-term home-treatment with rFVIII for subjects with hemophilia A. " 03/01/1988 - "Together with a previously published assay for FVIII-LC it has now become possible to measure the relative amounts of FVIII-HC and FVIII-LC in haemophilia A plasma and to study the separate expression of FVIII-HC and FVIII-LC by recombinant DNA technology. " 04/01/2004 - "Human recombinant DNA-derived antihemophilic factor in the treatment of previously untreated patients with hemophilia A: final report on a hallmark clinical investigation." 05/01/1995 - "Use of recombinant DNA-derived fVIII as well as gene therapy could make hemophilia treatment independent of blood-derived products. " 10/01/1990 - "Recombinant DNA methods in hemophilia A: carrier detection and prenatal diagnosis."
5.	Virus Diseases (Viral Diseases) 03/01/1988 - "The application of recombinant DNA techniques to the diagnosis of sexually transmitted virus infections." 06/01/1985 - "Recombinant DNA techniques are contributing to the understanding of the pathogeneses of genetic, neoplastic, and viral diseases, and are used in the diagnosis of certain genetic and viral diseases. " 04/01/1993 - "With the use of recombinant DNA technology, PCR has allowed a spectrum of advances in diagnostic pathology, specially in the fields of viral diseases, hematology and genetic diseases. " 09/01/1990 - "Detection of avian infectious bronchitis viral infection using in situ hybridization and recombinant DNA." 12/01/2011 - "For the control of these viral diseases, development of vaccines, either with classical methods or with recombinant DNA virus vectors, has been attempted over the years. "

Related Drugs and Biologics

1.	Vaccines
2.	Proteins (Proteins, Gene)
3.	Antigens
4.	Hepatitis B Vaccines (Hepatitis B Vaccine)
5.	Immunoglobulins (Immunoglobulin)
6.	Monoclonal Antibodies
7.	Hepatitis B Surface Antigens (HBsAg)
8.	hepatitis B hyperimmune globulin
9.	Insulin (Novolin)
10.	Interferon-alpha (Interferon Alfa)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Oral Medicine
4.	Fluoridation
5.	Intravenous Infusions