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DNA Helicases

Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate of DNA strands.
Also Known As:
ATP-Dependent DNA Helicases; DNA Helicase A; DNA Helicase E; DNA Helicase II; DNA Helicase III; ATP Dependent DNA Helicases; DNA Helicases, ATP-Dependent; Helicases, ATP-Dependent DNA; Helicases, DNA; Unwinding Proteins, DNA; DNA Unwinding Proteins
Networked: 86 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Brosh, Robert M: 11 articles (10/2013 - 05/2005)
2. Aggarwal, Monika: 4 articles (10/2013 - 04/2009)
3. Sommers, Joshua A: 4 articles (10/2013 - 08/2005)
4. Sharma, Sudha: 4 articles (01/2011 - 05/2005)
5. Seki, Masayuki: 3 articles (05/2014 - 08/2002)
6. Enomoto, Takemi: 3 articles (05/2014 - 08/2002)
7. Sung, Patrick: 3 articles (07/2010 - 05/2003)
8. Ellis, N A: 3 articles (11/2008 - 01/2000)
9. Doherty, Kevin M: 3 articles (09/2006 - 05/2005)
10. Jin, Weidong: 2 articles (06/2015 - 01/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Genomic Instability
3. Werner Syndrome (Werner's Syndrome)
4. Xeroderma Pigmentosum (Kaposi's Disease)
5. Bloom Syndrome (Syndrome, Bloom)

Related Drugs and Biologics

1. DNA (Deoxyribonucleic Acid)
2. Proteins (Proteins, Gene)
3. RecQ Helicases
4. Tumor Viral Antigens (Large T Antigen)
5. Transcription Factor TFIIH
6. Replication Protein A
7. DNA-Binding Proteins (DNA Binding Protein)
8. Fanconi Anemia Complementation Group Proteins
9. A-Form DNA (A-DNA)
10. Lamin Type A (Lamin A)

Related Therapies and Procedures

1. Adjuvant Chemotherapy