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DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)

A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catalyzes the elongation of oligo- or polydeoxynucleotide chains and is widely used as a tool in the differential diagnosis of acute leukemias in man. EC 2.7.7.31.
Also Known As:
Terminal Deoxynucleotidyl Transferase; Deoxynucleotidyl Transferase; Deoxynucleotidyltransferase; Desoxynucleotidyl Transferase; Desoxynucleotidyltransferase; Tdt Antigen; Terminal Deoxyribonucleotidyl Transferase; Addition Enzyme, Terminal; Antigen, Tdt; Deoxynucleotidyl Transferase, Terminal; Deoxyribonucleotidyl Transferase, Terminal; Deoxyribonucleotidyltransferase, Terminal; Enzyme, Terminal Addition; Nucleotidylexotransferase, DNA; Transferase, Deoxynucleotidyl; Transferase, Desoxynucleotidyl; Transferase, Terminal Deoxynucleotidyl; Transferase, Terminal Deoxyribonucleotidyl; Terminal Addition Enzyme; Terminal Deoxyribonucleotidyltransferase; Nucleoside-triphosphate:DNA deoxynucleotidylexotransferase
Networked: 1569 relevant articles (37 outcomes, 88 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Cuzzocrea, Salvatore: 13 articles (05/2010 - 02/2005)
2. Mazzon, Emanuela: 13 articles (05/2010 - 02/2005)
3. Bramanti, Placido: 12 articles (05/2010 - 02/2005)
4. Genovese, Tiziana: 12 articles (02/2010 - 02/2005)
5. Di Paola, Rosanna: 11 articles (05/2010 - 03/2006)
6. Kim, Sung-Hoon: 9 articles (08/2015 - 10/2004)
7. Muià, Carmelo: 9 articles (08/2008 - 02/2005)
8. Esposito, Emanuela: 8 articles (05/2010 - 07/2006)
9. Kim, Chang-Ju: 7 articles (08/2015 - 08/2002)
10. Wang, Jing: 7 articles (03/2015 - 12/2010)

Related Diseases

1. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
2. Neoplasms (Cancer)
3. Leukemia
4. Necrosis
5. Ischemia

Related Drugs and Biologics

1. Biotin (Vitamin H)
2. deoxyuridine triphosphate
3. Biological Markers (Surrogate Marker)
4. Caspase 3 (Caspase-3)
5. Fluorescein (Funduscein)
6. Proliferating Cell Nuclear Antigen (PCNA)
7. Uridine Triphosphate (UTP)
8. Deoxyuridine
9. triphosphoric acid (triphosphate)
10. Vincristine (Oncovin)

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Aftercare (After-Treatment)
3. Intraperitoneal Injections
4. Radioimmunotherapy
5. Intravenous Injections