DNA (Cytosine-5-)-Methyltransferases (DNA (Cytosine 5) Methyltransferase)

Enzymes that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the 5-position of CYTOSINE residues in DNA.

Also Known As:

DNA (Cytosine 5) Methyltransferase; Cytosine-5-Methylase, DNA; DNA Cytosine 5 Methylase; DNA (Cytosine-5-)-Methyltransferase; DNA Cytosine-5-Methylase; S-Adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase

Networked: 12 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ma, Yuhong: 1 article (01/2022)
2.	Will, Britta: 1 article (01/2022)
3.	Sacko, Koita: 1 article (07/2019)
4.	Shoyele, Sunday A: 1 article (07/2019)
5.	Thangavel, Karthik: 1 article (07/2019)
6.	Katanasaka, Yasufumi: 1 article (01/2018)
7.	Oshima, Kosei: 1 article (01/2018)
8.	Sano, Miho: 1 article (01/2018)
9.	Sano, Soichi: 1 article (01/2018)
10.	Walsh, Kenneth: 1 article (01/2018)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2022 - "In this issue of Cancer Discovery, Huang and colleagues define a new class of disease-associated DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A) variants with decreased de novo DNA methylation activity due increased proteasomal degradation that are able to drive clonal expansion of hematopoietic stem cells.See" 12/01/2010 - "The DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B) -579 G>T promoter polymorphism (rs1569686) influences gene function and has been associated with various malignancies. " 01/01/2015 - "Recently, large-scale sequencing has identified frequent ribonuclease type III (DICER1), CCCTC-binding factor (CTCF), ribosomal protein L22 (RPL22), DNA (cytosine-5-)-methyltransferase 3α (DNMT3A), transformation/transcription domain-associated protein (TRRAP), isocitrate dehydrogenase (IDH)1 and IDH2 hotspot mutations in diverse types of cancer. "
2.	Acute Erythroblastic Leukemia (Erythroleukemia) 05/01/1985 - "Friend murine erythroleukemia cells were found to contain three distinct species of DNA (cytosine-5-)-methyltransferase (DNA MeTase) whose relative proportions were a characteristic function of the proliferative state of the cells. " 09/01/1983 - "Dye-ligand chromatography on Cibacron blue F3GA-agarose has been used to resolve two species of DNA (cytosine-5-)-methyltransferase from nuclear extracts of uninduced Friend murine erythroleukemia cells. "
3.	Mastocytoma 10/15/1988 - "DNA (cytosine-5-)-methyltransferase was purified as a single polypeptide (190 kDa by SDS-PAGE) from mouse P815 mastocytoma cells. "
4.	Thymoma (Thymic Carcinoma) 07/23/2019 - "The ability of GMLHN to downregulate targeted oncoproteins Phosphorylated protein kinase, strain AK, Thymoma (Phosphorylated protein kinase B) (pAKT), Phosphorylated phosphoinositide 3-kinase (p-PI3K), DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B) and Myeloid Cell Leukemia Sequence 1 (MCL 1) was evaluated using western blot, while antiproliferative effect and ability to initiate apoptosis was also assessed in A549 cells. "
5.	Glioma (Gliomas) 04/01/2017 - "A total of six PcGs [chromobox protein homolog (CBX) 6, CBX7, PHD finger protein 1, enhancer of zeste homolog 2 (EZH2), DNA (cytosine-5-)-methyltransferase 3β (DNMT3B) and polyhomeotic-like protein 2] were identified to be associated with glioma grade. "

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