Disseminated Intravascular Coagulation

3571  relevant articles (96 outcomes, 153 trials/studies) found for this Disease

Coagulation, Disseminated Intravascular; Disseminated Coagulation, Intravascular; Intravascular Coagulation, Disseminated; Intravascular Disseminated Coagulation; Coagulation, Intravascular Disseminated; Coagulations, Disseminated Intravascular; Coagulations, Intravascular Disseminated; Coagulopathies, Consumption; Coagulopathy, Consumption; Consumption Coagulopathies; Disseminated Coagulations, Intravascular; Disseminated Intravascular Coagulations; Intravascular Coagulations, Disseminated; Intravascular Disseminated Coagulations; Consumption Coagulopathy

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Sepsis (Septicemia)
2.	Syndrome
3.	Thrombosis (Thrombus)
4.	Hemorrhage
5.	Venous Thrombosis (Deep-Vein Thrombosis)
554 Diseases and 2144 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Asakura, Hidesaku: 14 articles (10/2006 - 01/2002)
2.	Nakao, Shinji: 11 articles (10/2006 - 01/2002)
3.	Morishita, Eriko: 11 articles (10/2006 - 01/2002)
4.	Yamazaki, Masahide: 11 articles (10/2006 - 01/2002)
5.	Ontachi, Yasuo: 10 articles (10/2006 - 01/2002)
6.	Wada, Hideo: 8 articles (10/2005 - 07/2002)
7.	Asakura, H: 7 articles (01/2007 - 01/2001)
8.	Yoshida, Tomotaka: 7 articles (10/2006 - 04/2003)
9.	Omote, Mika: 6 articles (10/2006 - 05/2004)
10.	Miyamoto, Ken-ichi: 6 articles (10/2006 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Disseminated Intravascular Coagulation:

1.	Dacarbazine (DIC)FDA LinkGeneric 01/01/2000 - "First remission rates have increased to greater than 85% world wide, the incidence of disseminated intravascular coagulation (DIC) has declined dramatically, and 60% to 70% of patients with AML-M3 have achieved long term survival and are potentially cured." 01/01/1990 - "3) The patients with disseminated intravascular coagulation (DIC) showed statistically marked decrease of the XIIIa, the alpha 2PI, and the FN on admission and the first hospital day compared with those patients without DIC" 01/01/1987 - "In the absence of good clinical trials, the value of ATIII replacement therapy also remains obscure; its use in congenital deficiency is largely based on anecdote, and while it may cause more rapid correction of the hemostatic defect in patients with disseminated intravascular coagulation (DIC), any improvement in morbidity or mortality resulting from ATIII replacement remains to be demonstrated." 07/03/1978 - "The reduced response of the platelets in the newborn to these aggregating agents can be considered as a protection against disseminated intravascular coagulation (DIC), particularly in high-risk situations." 04/01/1997 - "The efficacy of treatment in relation to the disseminated intravascular coagulation (DIC) score when the treatment was begun showed that greater efficacy was achieved in Pre-DIC than in DIC patients" Get all the results and reference details, order at left...
2.	Antithrombin IIIIBA 01/01/1998 - "Antithrombin III (AT III) supplementation has proven to be effective in the treatment of disseminated intravascular coagulation" 08/01/1983 - "Replacement therapy with antithrombin III (AT-III) proved useful in the management of the consumption coagulopathy" 06/01/1988 - "Efficacy of antithrombin III in endotoxin-induced disseminated intravascular coagulation." 01/01/1987 - "Protection against disseminated intravascular coagulation and death by antithrombin-III in the Escherichia coli endotoxemic rat." 08/01/2007 - "Differences in antithrombin III activities by administration method in critical patients with disseminated intravascular coagulation: a pharmacokinetic study." Get all the results and reference details, order at left...
3.	Heparin (Liquaemin)FDA LinkGeneric 04/01/1980 - "Since the assay system is unaffected by fibrino(geno)lytic degradation products and heparin, it proved useful in monitoring the efficacy of heparin therapy for disseminated intravascular coagulation" 07/01/1976 - "Disseminated intravascular coagulation caused by the carpet viper (Echis carinatus): trial of heparin." 12/01/1999 - "In addition to treatment of the underlying disease, consumption coagulopathy was previously treated with heparin" 01/01/1992 - "In disseminated intravascular coagulation seen in patients with the gravest patterns of IBS, heparin may be indicated." 09/01/1991 - "CONCLUSIONS: The results suggest that heparin, in a dose of 10 IU/kg.hr iv, could possibly be safely used in patients at high risk of developing disseminated intravascular coagulation and in those patients with established disseminated intravascular coagulation." Get all the results and reference details, order at left...
4.	Thromboplastin (Tissue Factor)IBA 04/01/2008 - "Additionally, one should exercise caution if there is evidence of activated coagulation, such as that seen with excessive tissue factor release or disseminated intravascular coagulation" 01/01/2002 - "CONCLUSION: Because pathophysiology differed remarkably between the tissue factor- and lipopolysaccharide-induced disseminated intravascular coagulation models in rats, we recommend that they be assessed carefully as distinct entities to determine implications of their experimental and clinical use." 01/01/2002 - "OBJECTIVE: Tissue factor and lipopolysaccharide frequently have been used to induce disseminated intravascular coagulation in experimental animal models" 01/01/2002 - "Marked difference in pathophysiology between tissue factor- and lipopolysaccharide-induced disseminated intravascular coagulation models in rats." 12/01/2001 - "The tissue factor pathway in disseminated intravascular coagulation." Get all the results and reference details, order at left...
5.	Fibrinogen (Factor I)IBA 07/01/2006 - "Prolonged prothrombin time, 26 seconds (normal range 13-16 seconds); prolonged activated partial thromboplastin time, 61 seconds (normal range 26-38 seconds); positive disseminated intravascular coagulation studies evidenced by low fibrinogen, 74 mg/dL (normal range 160-350 mg/dL); and positive fibrinogen degradation products were also noted" 07/01/1982 - "Studies on fibrinogen heterogeneity in disseminated intravascular coagulation]" 12/01/2002 - "What role does the measurement of fibrinogen and its derivatives have in the diagnosis of disseminated intravascular coagulation?" 12/01/2001 - "Plasma fibrinogen is widely used in horse practice as an unspecific positive marker of inflammatory diseases; it is also lowered in disseminated intravascular coagulation" 02/15/2001 - "On admission non-survivors had a more pronounced degree of disseminated intravascular coagulation compared to survivors (platelet count 18000 (15000; 45000) G/l vs. 119.000 (111000; 152000) G/l, (p = 0.03); fibrinogen 67 (50; 108) mg/dl vs. 356 (234; 483) mg/dl, (p = 0.02); PTZ 28% (20%; 30%) vs. 44% (35%; 51%), (p = 0.05); aPTT 120 (120; 128) sec vs. 46 (44; 69) sec, (p = 0.001)" Get all the results and reference details, order at left...
6.	Protein CIBA 07/01/1985 - "Serial studies of protein C and its plasma inhibitor in patients with disseminated intravascular coagulation." 11/01/2004 - "The presence or absence of disseminated intravascular coagulation should not influence the decision to administer recombinant human activated protein C" 10/01/2004 - "Blood plasma resistance to activated protein C as a risk factor of disseminated intravascular coagulation in acute-poisoned patients]" 06/15/2003 - "Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice." 09/01/2000 - "Effect of activated human protein C on disseminated intravascular coagulation induced by lipopolysaccharide in rats." Get all the results and reference details, order at left...
7.	Factor Xa (Coagulation Factor Xa)IBA 01/01/1979 - "Disseminated intravascular coagulation was induced in dogs by infusion of tissue thrombokinase" 07/15/1991 - "DEGR-factor Xa blocks disseminated intravascular coagulation initiated by Escherichia coli without preventing shock or organ damage." 11/01/2000 - "Increased plasma levels of tissue factor pathway inhibitor-activated factor X complex in patients with disseminated intravascular coagulation." 10/01/2000 - "Tissue factor pathway inhibitor (TFPI) in disseminated intravascular coagulation: low levels of the activated factor X-TFPI complex." 09/01/1999 - "Monoclonal antibody specific for tissue factor pathway inhibitor-factor Xa complex: its characterization and application to plasmas from patients with disseminated intravascular coagulation and pre-disseminated intravascular coagulation." Get all the results and reference details, order at left...
8.	HirudinsIBA 02/01/1995 - "Recombinant hirudin for the treatment of disseminated intravascular coagulation in patients with haematological malignancy." 01/01/1991 - "Hirudin in disseminated intravascular coagulation." 01/01/1991 - "The efficacy of hirudin in preventing venous and arterial thrombosis and disseminated intravascular coagulation was demonstrated in various animal models" 03/01/1988 - "The efficacy of r-hirudin in preventing both venous and arterial thrombosis, vascular shunt occlusion or disseminated intravascular coagulation was demonstrated in rats" 06/28/1982 - "The efficacy of hirudin in preventing venous thrombosis, vascular shunt occlusion and disseminated intravascular coagulation in rats was demonstrated." Get all the results and reference details, order at left...
9.	ThrombinIBA 04/01/2006 - "Thrombin generation by exposure of blood to endotoxin: a simple model to study disseminated intravascular coagulation." 05/01/1984 - "In this study dogs were infused with thrombin, and disseminated intravascular coagulation developed" 02/01/1967 - "An electron microscopic study of thrombin-induced disseminated intravascular coagulation." 10/07/2004 - "Disseminated intravascular coagulation arises from an overwhelming of the haemostatic regulatory mechanisms leading to an excessive generation of thrombin and a failure of the normal inhibitory pathways to prevent systemic effects of this enzyme" 04/01/2004 - "Thrombin in urine was detected in glomerulonephritic patients but not in healthy volunteers or disseminated intravascular coagulation patients, which suggests that thrombin in urine may reflect thrombin generation by clotting activation in the glomerular lesion." Get all the results and reference details, order at left...
10.	Gabexate (Foy)IBA 11/01/1993 - "Treatment of disseminated intravascular coagulation with gabexate mesilate." 06/01/1988 - "Gabexate as a therapy for disseminated intravascular coagulation." 12/01/1986 - "Treatment of pre-disseminated intravascular coagulation state with gabexate mesilate (FOY)]" 01/01/1983 - "Protective effect of gabexate mesilate against experimental disseminated intravascular coagulation in rats." 05/01/1982 - "Protection of endotoxin-induced disseminated intravascular coagulation in rats by gabexate mesilate]" Get all the results and reference details, order at left...
653 Drugs and Important Bio-Agents and 3317 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 12/01/1983 - "Inspite of chemotherapy one twin died of disseminated intravascular coagulation with pulmonary haemorrhage; the other one, however, went into long-term remission" 01/01/2006 - "MEASUREMENTS AND RESULTS: Thirty-seven (69%) patients received chemotherapy because of extensive disease with organ involvement (54%), extensive disease without organ involvement (19%), severe disseminated intravascular coagulation (11%), and other reasons (16%)" 01/01/2004 - "One patient died 8 months after first admission to our hospital, another died of disseminated intravascular coagulation I month after admission, and the third was treated with hepatic arterial infusion chemotherapy and survived >36 months" 09/01/2001 - "Patient died of complications of malignancy-related disseminated intravascular coagulation without chemotherapy after confirming diagnosis was made three months later." 10/01/1998 - "OBJECTIVE: To detect the changes in blood coagulation system and clarify the related mechanisms of chemotherapy-induced disseminated intravascular coagulation" Get all the results and reference details, order at left...
2.	Ligation 04/01/1993 - "However, this activity decreased significantly after portal vein ligation, suggesting progression into irreversible disseminated intravascular coagulation" 02/01/1997 - "Function was lost to occlusion in 26 patients, infection in 9, and ligation for disseminated intravascular coagulation in 3. Thirteen patients underwent 18 shunt replacements" 03/01/1993 - "These included interruption of collateral vessels, intraoperative hypotension and disseminated intravascular coagulation, and distal splenic artery ligation" 02/01/1989 - "The procedure was successful in arresting the haemorrhage in 13 patients but 4 needed hysterectomy in spite of the ligation; 1 patient died from disseminated intravascular coagulation following surgery and 1 had cardiac arrest due to extensive blood loss during surgery and died 12 hours later" 09/01/1987 - "Deaths resulted from disseminated intravascular coagulation and bleeding, and bleeding and pulmonary failure after ligation of a patent ductus arteriosus" Get all the results and reference details, order at left...
3.	Surgical Instruments (Clip) 05/01/1997 - "After forceps delivery a massive postpartum haemorrhage as the result of a consumption coagulopathy occurred" 01/01/2003 - "There were no deaths in the absorbable clip group, but 1 of the 444 patients (0.23%) in the metal clip group died from disseminated intravascular coagulation on postoperative day 3. CONCLUSION: The results of this study suggest that absorbable clips are as safe and effective as standard metal clips for vessel and duct ligation in LC." Get all the results and reference details, order at left...
4.	Cesarean Section (Caesarean Section) 12/01/1991 - "Among the direct maternal deaths, 52% had disseminated intravascular coagulation and 25% had a cesarean section" 08/01/1981 - "Possibilities of development and prevention of disseminated intravascular coagulation during cesarean section]" 11/09/1998 - "Bleeding and disseminated intravascular coagulation following Cesarean section]" 08/01/1996 - "In women with HELLP syndrome there was a higher incidence of cesarean section (p < 0.05), disseminated intravascular coagulation (p < 0.001), and need for transfusion (p < 0.001) than in the other two groups" 09/01/2001 - "We describe a 27-year-old woman with disseminated intravascular coagulation and shock due to amniotic fluid embolism after Caesarean section who responded well to continuous hemodiafiltration (CHDF) therapy" Get all the results and reference details, order at left...
5.	Resuscitation 01/01/2005 - "After initial resuscitation, her recovery was complicated by development of disseminated intravascular coagulation and a large sub-capsular hepatic haematoma" 12/04/1976 - "Consumption coagulopathy is frequently observed in a resuscitation department" 08/01/2006 - "CONCLUSIONS: Accurate visual estimation of blood loss is known to facilitate timely resuscitation, minimising the risk of disseminated intravascular coagulation and reducing the severity of haemorrhagic shock" 01/01/1991 - "After resuscitation he developed adult respiratory distress syndrome and disseminated intravascular coagulation" 04/15/1985 - "A case of intentional ingestion of concentrated acid, in which both disseminated intravascular coagulation and acute respiratory insufficiency complicated initial resuscitation, is reported" Get all the results and reference details, order at left...
123 Therapies and Procedures and 462 more articles analyzed in the Full Patient-Physician Summary Report, order at left...