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Dihydropteridine Reductase (6,7 Dihydropteridine Reductase)

An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.
Also Known As:
6,7 Dihydropteridine Reductase; 6,7-Dihydropteridine Reductase; Reductase, 6,7-Dihydropteridine; Reductase, Dihydropteridine; NAD(P)H:6,7-dihydropteridine oxidoreductase
Networked: 87 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Blau, Nenad: 5 articles (01/2021 - 03/2008)
2. Ponzone, Alberto: 4 articles (11/2016 - 03/2004)
3. Thöny, Beat: 3 articles (01/2021 - 01/2011)
4. Porta, Francesco: 3 articles (11/2016 - 03/2008)
5. Spada, Marco: 3 articles (11/2016 - 03/2004)
6. Khatami, Shohreh: 2 articles (09/2021 - 10/2013)
7. Raiman, Julian: 2 articles (01/2018 - 02/2015)
8. Furujo, Mahoko: 2 articles (01/2017 - 01/2014)
9. Hyland, Keith: 2 articles (02/2015 - 01/2013)
10. Hoffmann, Georg F: 2 articles (06/2011 - 03/2008)

Related Diseases

1. Phenylketonurias (Phenylketonuria)
2. Seizures (Absence Seizure)
3. Pheochromocytoma
4. Fetal Growth Retardation (Intrauterine Growth Retardation)
5. Inborn Genetic Diseases (Disease, Hereditary)

Related Drugs and Biologics

1. Neurotransmitter Agents (Neurotransmitter)
2. Levetiracetam (Keppra)
3. sapropterin (tetrahydrobiopterin)
4. Enzymes
5. GTP Cyclohydrolase (GTP Cyclohydrolase I)
6. 6-pyruvoyltetrahydropterin synthase (PTPS)
7. Serotonin (5 Hydroxytryptamine)
8. Antibodies
9. Pterins
10. Neopterin

Related Therapies and Procedures

1. Therapeutics