Hydromorphone (Dilaudid)

12/09/2004 - "This observational study confirms the good pain-relieving efficacy of sustained-release hydromorphone together with very good tolerability and very good compliance. "
10/13/2023 - "Our objective was to determine if oral hydromorphone (2 mg) given six hours after a single-injection interscalene block for arthroscopic shoulder surgery leads to a clinically significant reduction in the severity of rebound pain. "
08/01/2009 - "Safety and efficacy of rapid titration using 1mg doses of intravenous hydromorphone in emergency department patients with acute severe pain: the "1+1" protocol."
06/01/2023 - "The primary objective was to determine whether PCA or IVP hydromorphone is more effective in controlling VOC pain determined by a reduction in mean absolute difference pain intensity (MPI) from baseline to discharge. "
01/01/2021 - "Hydromorphone lacks these characteristics potentially leading to a more predictable drug delivery and improved pain and sedation management among ECMO patients. "

09/15/2009 - "The results of this extension study suggest that long-term repeated dosing with once-daily OROS(R) hydromorphone can be beneficial in the continuing management of persistent, moderate-to-severe cancer pain."
05/01/1996 - "A randomized, double-blind, double-dummy, crossover trial comparing the safety and efficacy of oral sustained-release hydromorphone with immediate-release hydromorphone in patients with cancer pain. "
09/15/1994 - "Controlled release hydromorphone administered every 12 hours is as effective as immediate release hydromorphone administered every 4 hours in the management of patients with chronic severe cancer pain. "
05/01/1996 - "To evaluate the safety and efficacy of a new slow-release preparation of hydromorphone (SRH) in the treatment of cancer pain. "
09/15/2009 - "An open-label, 1-year extension study of the long-term safety and efficacy of once-daily OROS(R) hydromorphone in patients with chronic cancer pain."

10/01/2014 - "Clinical Usefulness of Hydromorphone-OROS in Improving Sleep Disturbances in Korean Cancer Patients: A Multicenter, Prospective, Open-Label Study."
09/01/2022 - "Hydromorphone for dyspnoea in terminally ill patients with cancer: case series."
12/01/2020 - "[Hydromorphone in Cancer Patients-A Retrospective Study]."
05/01/2002 - "Hydromorphone metabolites: isolation and identification from pooled urine samples of a cancer patient."
03/01/2001 - "Hydromorphone: pharmacology and clinical applications in cancer patients."

10/01/2011 - "Intrathecal hydromorphone for cesarean delivery: in search of improved postoperative pain management: a case report."
01/01/2012 - "The purpose of this study was to determine the dose of intrathecal hydromorphone necessary to achieve postoperative pain relief after arthroscopic knee surgery. "
01/01/2023 - "Intraoperative hydromorphone decreases postoperative pain: an instrumental variable analysis."
12/01/2022 - "The secondary outcomes included postoperative anxiety and depression scores using the Hospital Anxiety and Depression Scale, postoperative pain using the visual analog scale, postoperative hydromorphone consumption, and risk factors associated with PSD. "
01/01/2021 - "Increasing intraoperative hydromorphone does not decrease postoperative pain: a retrospective observational study."

01/01/2016 - "Efficacy of a new once daily hydromorphone formulation in comparison with twice daily administration in chronic pain: a randomized, double-blind, cross-over study."
09/01/2011 - "We studied the efficacy of OROS(®) hydromorphone in the treatment of chronic pain, the appearance and frequency of any adverse effects, the impact upon quality of life. "
03/01/2009 - "To assess the safety and efficacy of long-term repeated dosing of OROS hydromorphone in chronic pain patients. "
03/01/2009 - "Long-term safety, tolerability, and efficacy of OROS hydromorphone in patients with chronic pain."
09/01/2011 - "Clinical efficacy of OROS® hydromorphone in patients suffering from severe chronic pain: A Study undertaken in routine clinical practice."