Dieldrin

An organochlorine insecticide whose use has been cancelled or suspended in the United States. It has been used to control locusts, tropical disease vectors, in termite control by direct soil injection, and non-food seed and plant treatment. (From HSDB)

Also Known As:

Networked: 281 relevant articles (3 outcomes, 34 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Martyniuk, Christopher J: 6 articles (01/2021 - 08/2010)
2.	Liu, Bin: 5 articles (01/2021 - 08/2008)
3.	Brooke, B D: 5 articles (09/2019 - 06/2000)
4.	Anantharam, V: 4 articles (04/2010 - 12/2001)
5.	Kanthasamy, A G: 4 articles (04/2010 - 12/2001)
6.	Coetzee, M: 4 articles (03/2007 - 06/2000)
7.	Grandjean, P: 4 articles (01/2001 - 02/2000)
8.	Høyer, A P: 4 articles (01/2001 - 02/2000)
9.	Jørgensen, T: 4 articles (01/2001 - 02/2000)
10.	Sharma, Tusha: 3 articles (01/2021 - 10/2019)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2020 - "Although the exact mechanism is not fully understood, previous studies from our laboratory and others have shown that dieldrin induced liver tumors in mice through a non-genotoxic mechanism acting on tumor promotion stage. " 01/01/2009 - "This study indicates that developmental exposure to the environmental contaminant dieldrin causes increased tumor burden in genetically predisposed mice. " 01/01/2009 - "The objective of this study was to define the effect of developmental exposure to environmentally relevant concentrations of dieldrin, on mammary tumor development in the offspring. " 10/05/1999 - "Also, recent experimental studies provide a plausible mode of action to explain the mouse specificity of dieldrin-induced hepatocarcinogenesis and call into question the relevance of this activity to human cancer risk. " 01/01/2020 - "The previously observed oxidative stress/damage may be an associated or modifying factor in the process of dieldrin-induced liver tumor formation subsequent to the CAR activation."
2.	Malaria 04/01/2012 - "This study was conducted to determine the knockdown resistance (kdr) alleles, dieldrin resistance alleles, and entomological inoculation rates (EIRs) of malaria vectors in lower Moshi irrigation schemes for the mitigation of disease transmission. " 06/19/2012 - "Genetic sex separation of the malaria vector, Anopheles arabiensis, by exposing eggs to dieldrin." 09/01/2006 - "Dieldrin resistance in the malaria vector Anopheles gambiae in Ghana." 12/01/2002 - "We are interested in generating a Y-autosome translocation of the Resistance to dieldrin (Rdl) locus in the malaria vector mosquito Anopheles stephensi Liston (Diptera: Culicidae), for use in sterile insect release. " 02/01/1982 - "The factor was not generated in mice administered dieldrin and infected with malaria nor in mice administered only dieldrin nor in mice only infected with Leishmania. "
3.	Parkinson Disease (Parkinson's Disease) 01/01/2020 - "Epidemiological studies have implicated that environmental exposure to organochlorine pesticides including dieldrin is a risk factor for the development of Parkinson's disease. " 01/01/2019 - "Developmental Dieldrin Exposure Alters DNA Methylation at Genes Related to Dopaminergic Neuron Development and Parkinson's Disease in Mouse Midbrain." 03/30/2010 - "These results provide some support for an increased risk of Parkinson disease with exposure to dieldrin, but chance or exposure correlation with other less persistent pesticides could contribute to our findings." 10/22/2008 - "Here we further investigated dieldrin toxicity in a dopaminergic neuronal cell model of Parkinson's disease, namely N27 cells, using biochemical, immunochemical, and flow cytometric analyses. " 10/22/2008 - "Dieldrin has been reported to be one of the environmental factors correlated with Parkinson's disease and may selectively destroy dopaminergic neurons. "
4.	Breast Neoplasms (Breast Cancer) 12/01/2000 - "Our study did not confirm the recent findings of a Danish study of increased concentrations of dieldrin in the serum of breast cancer cases. " 02/01/2008 - "The human breast cancer cell line MDA-MB-231 was treated with dieldrin and proliferation, viability and resistance to anoikis were measured. " 02/01/2008 - "We hypothesize that dieldrin promotes breast cancer by increasing survival of breast cancer cells. " 02/01/2008 - "Dieldrin promotes resistance to anoikis in breast cancer cells in vitro." 11/25/2000 - "Breast cancer and dieldrin."
5.	Poisoning 01/01/1977 - "In a study of dieldrin toxicity to breeding and nonbreeding bob-white quail (Colinus virginianus), breeding birds of both sexes on long photoperiods were more susceptible to dieldrin poisoning than nonbreeding birds, although some differences were not statistically significant at the .10 level. " 12/01/1957 - "[Study on the 1st cases of dieldrin poisoning & the application of xenodiagnosis to humans]." 05/01/1987 - "The diagnosis of poisoning with dieldrin was based upon the presence of characteristic clinical signs, pathological findings and the detection of residues of dieldrin in tissues. " 05/01/1984 - "At the onset of poisoning, 20-30 min following the application of dieldrin, outer glial cells exhibited slight increase in electron opacity while the inner glial cells showed increase in lysosomal activity. " 04/07/1984 - "Dieldrin poisoning in cats."

Related Drugs and Biologics

1.	Insecticides
2.	Aldrin (Isodrin)
3.	Pesticides
4.	Carcinogens
5.	teleocidins
6.	Dichlorodiphenyl Dichloroethylene (DDE)
7.	Hexachlorocyclohexane (gamma-Hexachlorocyclohexane)
8.	DDT
9.	Chlorinated Hydrocarbons
10.	Heptachlor

Related Therapies and Procedures

1.	Electrodes (Electrode)
2.	Diet Therapy (Therapy, Diet)
3.	Topical Administration