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Diazooxonorleucine

An amino acid that inhibits phosphate-activated glutaminase and interferes with glutamine metabolism. It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil. (From Merck Index, 11th ed)
Also Known As:
6-Diazo-5-oxo-L-norleucine; 6 Diazo 5 oxo L norleucine; Norleucine, 6-diazo-5-oxo-
Networked: 34 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lee, Chen-Fang: 1 article (10/2015)
2. Gordon, Emile B: 1 article (10/2015)
3. Tran, Tuan M: 1 article (10/2015)
4. Waisberg, Michael: 1 article (10/2015)
5. Hart, Geoffrey T: 1 article (10/2015)
6. Pierce, Susan K: 1 article (10/2015)
7. Kim, Ann S: 1 article (10/2015)
8. Hamilton, Sara E: 1 article (10/2015)
9. Pena, Mirna: 1 article (10/2015)
10. Akkaya, Munir: 1 article (10/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
3. Carcinoma (Carcinomatosis)
4. Sarcoma (Soft Tissue Sarcoma)
5. Mesothelioma

Related Drugs and Biologics

1. Glutaminase
2. Glutamic Acid (Glutamate)
3. Carbenoxolone
4. Norleucine
5. Glutamine (L-Glutamine)
6. Aclarubicin
7. lonidamine
8. Azaserine
9. acivicin (AT 125)
10. Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Analgesia