|1.||Type 1 Diabetes Mellitus (Autoimmune Diabetes)
|2.||Type 2 Diabetes Mellitus (MODY)
|3.||Hypoglycemia (Reactive Hypoglycemia)
|1.||Huang, Gan: 28 articles (12/2015 - 01/2003)|
|2.||Ricordi, Camillo: 28 articles (07/2012 - 12/2002)|
|3.||Sanjeevi, C B: 21 articles (04/2007 - 05/2000)|
|4.||Li, Xia: 20 articles (05/2015 - 01/2003)|
|5.||Bluestone, Jeffrey A: 20 articles (09/2012 - 05/2002)|
|6.||Zhou, Zhiguang: 19 articles (12/2015 - 11/2003)|
|7.||Yang, Lin: 18 articles (05/2015 - 01/2003)|
|8.||Eisenbarth, George S: 18 articles (02/2014 - 04/2002)|
|9.||Myśliwiec, Małgorzata: 17 articles (10/2014 - 01/2002)|
|10.||Lernmark, Ake: 17 articles (06/2014 - 06/2002)|
|1.||Insulin (Novolin)FDA Link
08/01/1990 - "Therefore, most studies have failed to demonstrate improved glycemic control after adding sulfonylurea to insulin therapy in patients with insulin-dependent diabetes mellitus. "
09/01/2014 - "The life expectancy of Type 1 diabetes mellitus (T1DM) dramatically improved after the discovery of insulin in 1922, but was still 25 years shorter than that of non-diabetic population. "
10/01/1993 - "Moreover, after the clinical onset of IDDM, most patients experience a transitory period of improved insulin secretion. "
07/01/2002 - "Diabetic patients undergo an important oxidative stress that is nearly corrected for IDDM, but only partially improved for ITDM2, although length of insulin treatment and HbA1c values are similar, suggesting metabolic differences between the two types of diabetes."
12/01/1991 - "Insulin replacement is the mainstay of treatment in IDDM; however, optimal therapy requires a careful balance of food, insulin, and physical activity. "
|2.||Glucose (Dextrose)FDA LinkGeneric
03/01/1998 - "Significantly greater concentrations of glucose were seen in saliva and serum in children with IDDM. "
07/01/1984 - "Normalization of glucose tolerance by means of GCIIS was associated with significant improvement of lipid metabolism in IDDM. "
09/01/2015 - "To determine whether a weight-based hypoglycaemia treatment using 0.3 g/kg (or 0.2 g/kg) glucose effectively treats adults with Type 1 diabetes mellitus compared with an internationally recommended 15-g treatment. "
08/01/2011 - "The aim of this study was to evaluate the efficacy of short-term continuous glucose monitoring system (CGMS) application in improvement of glycemic control in pediatric type 1 diabetes mellitus (T1DM) patients. "
06/01/1997 - "The Glucose Evaluation Trial for Remission (GETREM): A European effort to evaluate insulin-dependent diabetes mellitus in the first year after diagnosis."
|3.||Blood Glucose (Blood Sugar)IBA
03/01/1989 - "Our data suggest that clinic-based problem-solving groups can be more effective with young adolescents with IDDM than conventional treatment in preventing the expected deterioration in blood glucose."
08/01/1998 - "In the present study, we have examined the effect of an improved blood glucose control on plasma levels of hydroperoxides in patients with IDDM. "
06/01/1997 - "In patients with IDDM our studies demonstrated the limitations of traditional clinical judgement and the laboratory procedures in providing an accurate assessment of blood glucose control and that knowledge of HbA1c values allowed the clinician to identify patients in poor glycemic control and lead to improvement in glycemic control. "
09/01/1996 - "Microangiopathy is retarded by improved blood glucose control in patients with IDDM. "
08/01/1989 - "Improved blood glucose control, without 'near normoglycaemia', delayed the progression of nephropathy in patients with IDDM and retinopathy."
07/01/1998 - "To investigate the role of puberty on spontaneous clinical remission and on secretion of residual C-peptide during the first year of type 1 diabetes mellitus, we studied 77 pre-pubertal, 39 pubertal and 41 post-pubertal type 1 diabetic patients. "
01/01/1998 - "In addition, replacement of C-peptide during a period of 1-3 months has been shown to improve renal function as well as autonomic and sensory nerve function in IDDM patients. "
01/01/2007 - "At present, in view of numerous studies concerning its structure, membrane binding and biological functions, C-peptide seems to constitute a crucial role in the pathogenesis of complications in diabetes mellitus type 1 (DM1). "
04/01/2005 - "Recent studies have demonstrated that replacement of C-peptide to normal physiological concentrations in IDDM patients either on a short-term basis (1-3 hours) or on a prolonged administration (1-3 months) was accompanied by improvements in renal glomerular and tubular function. "
05/01/2004 - "The study included 20 participants with C-peptide-deficient Type 1 diabetes mellitus. "
|5.||Cyclosporine (Ciclosporin)FDA LinkGeneric
09/01/1992 - "Several studies have demonstrated the efficacy of cyclosporin A in modifying the initial course of Type 1 (insulin-dependent) diabetes mellitus in older children and adults but none have reported the effects in very young children. "
09/01/1987 - "We have developed a protocol of prophylactic cyclosporin A administration which confers complete and permanent protection against insulin-dependent diabetes mellitus in diabetes-prone BioBreeding rats. "
09/01/2010 - "Administration of high-dose cyclosporin (cyclo) has been demonstrated to induce remission of type 1 diabetes mellitus (T1D). "
09/01/1987 - "Cyclosporin A prophylaxis initiated later, but still before the onset of clinical symptoms (8-9 weeks), and terminated at 22-23 weeks, was only partially effective; 5/20 (25%) of cyclosporin A-treated rats developed insulin-dependent diabetes mellitus, compared to 60% (12/20) of controls (p less than 0.05). "
04/01/1988 - "The subjects were drawn from a pilot study (The Canadian Open Study on the effects of immunosuppression with Cyclosporine in Type 1 Diabetes Mellitus) in which 50% of the patients demonstrated remission during one year of cyclosporine administration. "
09/01/1996 - "Thus, p277 peptide therapy, marked by the induction of Th2-type antibodies, can be effective in toxin-induced autoimmune diabetes."
02/01/2006 - "Measurement of antigliadin antibodies in patients with diabetes mellitus type 1 helped in the selection of patients to undergo jejunal biopsy. "
02/01/2003 - "In mouse models of autoimmune diabetes, CD3-specific antibodies induce stable disease remission by restoring tolerance to pancreatic beta-cells. "
08/01/1996 - "Although the positivity was low, the detection of hsp60 antibodies may be helpful for diagnosis of IDDM especially in GAD65 Ab- or JCA-negative Japanese patients."
04/01/1980 - "Pancreatic islet-cell antibodies (I.C.Ab.) were detected in the sera of 6 of 123 patients with insulin-dependent diabetes mellitus of recent onset, compared with only 2 positive results among the 434 control sera. "
|7.||insulin LISPRO (Humalog)FDA Link
05/01/1999 - "Long-term efficacy of humalog in subjects with Type 1 diabetes mellitus."
08/01/1997 - "Strategies toward improved control during insulin lispro therapy in IDDM. "
03/01/1997 - "Prolonged efficacy of short acting insulin Lispro in combination with human ultralente in insulin-dependent diabetes mellitus."
09/01/2008 - "We simulate pulsatile implementations of a basal rate profile over a day on a type 1 diabetes mellitus patient using insulin lispro. "
01/01/2003 - "Pregnancy outcome in Type 1 diabetes mellitus treated with insulin lispro (Humalog)."
|8.||Streptozocin (Streptozotocin)FDA Link
09/25/2010 - "A few studies reported that Cr might also have some beneficial effects in people with type 1 diabetes mellitus and in streptozotocin-treated rats, but direct beneficial effects of Cr on pancreatic beta cells have not been proven. "
08/01/2010 - "The aim of this study is to investigate the therapeutic effect of RegIII-proinsulin-pBudCE4.1 plasmid on streptozotocin (STZ)-induced type 1 diabetes mellitus and its underlying mechanisms. "
12/01/2009 - "The aim of this paper is to study the myocardial damage secondary to long-term streptozotocin-induced type 1 diabetes mellitus (DM1). "
11/15/2009 - "In the present study, we evaluated whether TLR3 and TLR9, recognizing microbial dsDNA and CpG-containing DNA sequences, respectively, play a role in the protection from experimental autoimmune diabetes induced in C57BL/6 mice by streptozotocin. "
05/01/2009 - "Mechanistic studies examining the effects of Type 1 diabetes mellitus (T1DM) on skeletal muscle have largely relied on streptozotocin-induced diabetic (STZ) rodents. "
12/01/1998 - "The comparison of examined groups showed statistically significant higher susceptibility on the oxidation of chosen lipoproteins in pregnant with IDDM. "
07/01/1991 - "Abnormal clearance of postprandial Sf 100-400 plasma lipoproteins in insulin-dependent diabetes mellitus."
12/01/2001 - "In conclusion, children with type 1 diabetes mellitus included in this study did not have high-risk lipoprotein profiles at this early stage of life. "
12/01/1998 - "The aim of study was estimation of susceptibility on the process of oxidation of selected lipoproteins of pregnant women with IDDM in II, III trimester of pregnancy. "
05/01/1998 - "This study suggests that moderate alcohol consumption has no beneficial effect on the lipoprotein profile in IDDM men. "
|10.||Insulin-Like Growth Factor I (IGF-1)IBA
06/01/2015 - "A significant reduction of serum IGF-I levels was observed in patients with type 1 diabetes mellitus (T1DM). "
07/01/1996 - "Higher rate of clearance of the latter may be the reason for the low IGF-I levels we observed in children with IDDM. "
01/01/2013 - "A few studies have investigated the serum IGF-1 level at the onset of type 1 diabetes mellitus (T1DM) in children. "
07/01/1996 - "The role of recombinant human IGF-I in the treatment of IDDM needs to be tested by long-term controlled trials."
01/01/2015 - "Eighteen TM patients with IDDM (94.7 %) and ten non-diabetic patients (32.2 %) had IGF-1 levels below the 2.5(th) percentile of the normal values for the Italian population. "
|1.||Transplantation (Transplant Recipients)
07/01/2014 - "Pancreatic islet transplantation has emerged as an effective treatment for type 1 diabetes mellitus, but its use is limited due to an insufficient supply of cadaveric pancreata. "
01/01/2012 - "Parenteral administration of anti-CD3 monoclonal antibody is an approved therapy for transplantation in humans and is effective in autoimmune diabetes. "
06/01/2009 - "Pancreatic islet transplantation is a promising therapeutic treatment for type 1 diabetes mellitus. "
01/01/2009 - "Pancreatic islet transplantation has the potential to be an effective treatment for type 1 diabetes mellitus. "
11/15/2008 - "Parenteral administration of anti-CD3 monoclonal antibody is an approved therapy for transplantation in humans and is effective in autoimmune diabetes. "
|2.||Islets of Langerhans Transplantation
08/01/2005 - "Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs best medical therapy in type 1 diabetes mellitus."
03/27/1999 - "The findings have potential implications for islet transplantation as well as improved and more cost-effective therapy for IDDM."
01/01/2009 - "Islet transplantation has recently emerged as an effective therapy and potential cure for type 1 diabetes mellitus. "
02/01/2008 - "We conclude that in islet transplantation and autoimmune diabetes, ICOS blockade can be effective in inhibiting alloimmunity and preventing autoimmunity but is ineffective in inhibiting recurrence of autoimmunity."
04/27/1994 - "Islet transplantation can provide a therapeutic option for patients who suffer from type 1 diabetes mellitus, especially if current aggressive immunosuppression could be eliminated. "
12/01/1994 - "PKT has become an important option in selected IDDM patients being considered for kidney transplantation because of its ability to offer superior glycemic control and improved quality of life. "
05/01/2005 - "Simultaneous pancreas-kidney transplantation (SPK) has evolved as an effective treatment for patients with end-stage nephropathy due to type 1 diabetes mellitus. "
06/21/2002 - "The pancreas kidney transplantation (PKTx) currently is the only treatment for cure for patients with diabetes mellitus Type 1. Despite the availability of organs and the need for therapy the PKTx rate is much lower in Germany than it is in the United States. "
10/01/2009 - "The aim of the study was to compare the quality of life (QOL) of patients with IDDM and CRF subjected to SPK or kidney transplantation alone (KTA). "
05/01/2015 - "Renal transplantation in type 1 diabetes mellitus: an unusual case report."
04/01/2008 - "Pancreas transplantation is currently considered to be the most reliable and effective treatment for insulin-dependent diabetes mellitus (also called type 1 diabetes). "
12/01/2010 - "Simultaneous kidney and pancreas transplantation (SKPT) has become an effective treatment for patients who have diabetes mellitus type I with advanced nephropathy. "
03/01/1997 - "To determine the safety and efficacy of solitary pancreas transplantation in the treatment of IDDM. "
09/01/2003 - "Solitary pancreas or combined kidney-pancreas transplantation is currently the only therapeutic procedure for complete resolution of diabetes mellitus type I. The aim of the present study is to investigate the role of multislice computed tomography (MSCT) in the follow-up of patients subjected to solitary pancreas or combined kidney-pancreas transplantation. "
10/01/2000 - "The purpose of this study was to find out whether prolonged normoglycemia, as achieved by a successful pancreas transplantation, can improve survival in patients with insulin-dependent diabetes mellitus. "
12/01/2005 - "To evaluate the safety, feasibility, and clinical efficacy of percutaneous transhepatic injection of beta-cell grafts in patients with type 1 diabetes mellitus. "
12/01/2004 - "Optimized parameters for microencapsulation of pancreatic islet cells: an in vitro study clueing on islet graft immunoprotection in type 1 diabetes mellitus."
05/01/1997 - "In terms of islets, as problems of human islet yield and purity are gradually being overcome, the problem of islet graft-directed immune destruction hampers the success of ongoing clinical trials in IDDM patients. "
12/27/1996 - "Experimental studies by Bartlett et al. on the BB rat model suggest that whole pancreas transplants are not susceptible to recurrent autoimmune diabetes. "
10/01/2015 - "Pancreas transplant is an effective long-term treatment modality for complicated type 1 diabetes mellitus. "