Dextromethorphan (Levomethorphan)

Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Also Known As:
Levomethorphan; Racemethorphan; Delsym; Dextromethorphan Hydrobromide; Dextromethorphan Hydrochloride; Dextromethorphan Hydrobromide, (+-)-Isomer; Dextromethorphan Hydrobromide, Monohydrate; Dextromethorphan, (+-)-Isomer; l-Methorphan; Hydrobromide, Dextromethorphan; Hydrochloride, Dextromethorphan; d-Methorphan; Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-
Networked: 539 relevant articles (60 outcomes, 110 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results


1. Hong, Jau-Shyong: 13 articles (11/2014 - 04/2003)
2. Kim, Hyoung-Chun: 7 articles (01/2011 - 01/2003)
3. Shin, Eun-Joo: 6 articles (10/2010 - 01/2003)
4. Weinbroum, Avi A: 6 articles (11/2006 - 09/2002)
5. Ben-Abraham, R: 6 articles (11/2006 - 06/2000)
6. Pope, Laura E: 5 articles (11/2014 - 10/2004)
7. Tao, Pao-Luh: 5 articles (12/2012 - 11/2004)
8. Paul, Ian M: 5 articles (02/2012 - 07/2004)
9. Weinbroum, A A: 5 articles (08/2001 - 06/2000)
10. Lu, Ru-Band: 4 articles (11/2014 - 05/2012)

Related Diseases

1. Cough
2. Seizures (Seizure)
3. Pain (Aches)
4. Postoperative Pain
5. Respiratory Tract Infections (Respiratory Tract Infection)

Related Drugs and Biologics

1. N-Methylaspartate (NMDA)
2. Codeine (Codeine Phosphate)
3. Ketamine
4. Antitussive Agents (Antitussives)
5. Diphenhydramine (Benadryl)
6. Quinidine (Chinidin)
7. Dextrorphan
8. Dizocilpine Maleate (Dizocilpine)
9. Guaifenesin
10. Expectorants (Mucolytics)

Related Therapies and Procedures

1. Analgesia
2. Premedication
3. Aftercare (After-Treatment)
4. Drug Therapy (Chemotherapy)
5. Patient-Controlled Analgesia (Analgesia, Patient Controlled)

blog comments powered by Disqus
for Cough,
Ranking and Evidence

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. Analytic charts allow you and your physicians to see at a glance the treatment options—including new, promising, off-label and experimental.
  • Free Updates for 1 Year
  • All 563 Outcomes
  • Top 200 Key Drugs and Biologics
  • Top 50 Key Therapies and Procedures
  • Detailed History Charts
  • Full Research Evidence References
  • Sample PDF Report on Psoriasis >>
Price:$24.95 USD & Delivery via PDF download
updates for 1 year
Research Interface PRO

Rapidly retrieve clinical outcome summaries for all evidence of drug efficacy against any disease in seconds. Click "Charts" to view graphs of relative efficacy of all drugs against any known disease. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time. Save hours of search and analysis time:
Price:$490.00 USD access via web interface
1 year subscription
Request Bulk Institution License Details >>