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Dextromethorphan (Levomethorphan)

Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Also Known As:
Levomethorphan; Racemethorphan; Delsym; Dextromethorphan Hydrobromide; Dextromethorphan Hydrochloride; Dextromethorphan Hydrobromide, (+-)-Isomer; Dextromethorphan Hydrobromide, Monohydrate; Dextromethorphan, (+-)-Isomer; l-Methorphan; Hydrobromide, Dextromethorphan; Hydrochloride, Dextromethorphan; d-Methorphan; Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-
Networked: 555 relevant articles (61 outcomes, 111 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Hong, Jau-Shyong: 14 articles (10/2015 - 04/2003)
2. Weinbroum, Avi A: 7 articles (03/2015 - 09/2002)
3. Kim, Hyoung-Chun: 7 articles (01/2011 - 01/2003)
4. Tao, Pao-Luh: 6 articles (01/2015 - 11/2004)
5. Shin, Eun-Joo: 6 articles (10/2010 - 01/2003)
6. Ben-Abraham, R: 6 articles (11/2006 - 06/2000)
7. Chang, Yun-Hsuan: 5 articles (10/2015 - 05/2012)
8. Chen, Shiou-Lan: 5 articles (10/2015 - 05/2012)
9. Lu, Ru-Band: 5 articles (10/2015 - 05/2012)
10. Lee, Sheng-Yu: 5 articles (10/2015 - 05/2012)

Related Diseases

1. Cough
2. Seizures (Seizure)
3. Pain (Aches)
4. Postoperative Pain
5. Respiratory Tract Infections (Respiratory Tract Infection)

Related Drugs and Biologics

1. N-Methylaspartate (NMDA)
2. Codeine (Codeine Phosphate)
3. Ketamine
4. Antitussive Agents (Antitussives)
5. Quinidine (Chinidin)
6. Diphenhydramine (Benadryl)
7. Dextrorphan
8. Dizocilpine Maleate (Dizocilpine)
9. Guaifenesin
10. Expectorants (Mucolytics)

Related Therapies and Procedures

1. Analgesia
2. Premedication
3. Aftercare (After-Treatment)
4. Drug Therapy (Chemotherapy)
5. Patient-Controlled Analgesia (Analgesia, Patient Controlled)