Drug Eruptions (Drug Eruption)

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705 relevant articles (6 outcomes, 19 trials/studies) found for this Disease

Description: Adverse cutaneous reactions caused by ingestion, parenteral use, or local application of a drug. These may assume various morphologic patterns and produce various types of lesions.

Also Known As:

Drug Eruption; Eruption, Drug; Eruptions, Drug; Dermatitis Medicamentosa; Dermatitis, Adverse Drug Reaction

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Eosinophilia
2.	Fever (Fevers)
3.	Dyspnea (Shortness of Breath)
4.	Hypersensitivity (Allergy)
5.	Drug Eruptions (Drug Eruption)
141 Diseases and 192 more articles analyzed in the Research Interface, order at left...

Experts

1.	Kurokawa, Ichiro: 5 articles (10/2005 - 11/2002)
2.	Fonseca, E: 3 articles (04/2008 - 09/2004)
3.	Ozkaya, Esen: 3 articles (01/2008 - 07/2005)
4.	Heikkilä, H: 3 articles (07/2004 - 04/2000)
5.	Ozkaya, E: 2 articles (05/2008 - 05/2007)
6.	Almagro, M: 2 articles (04/2008 - 04/2008)
7.	Mahendra, Aneet: 2 articles (09/2006 - 11/2005)
8.	Gupta, Sunita: 2 articles (09/2006 - 11/2005)
9.	Gupta, Sanjeev: 2 articles (09/2006 - 11/2005)
10.	Umehara, Makiko: 2 articles (10/2005 - 05/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Drug Eruptions:

1.	Amoxicillin (Wymox)FDA LinkGeneric 02/01/1976 - "2) Amoxicillin was effective against: Staphylococcus aureus in 10 of 11 patients (90.9%) Staphylococcus epidermidis in 2 of 2 patients (100%) Streptococcus hemolyticus in 3 of 4 patients (75%) Streptococcus viridans in 1 of 1 patient (100%) Diplococcus pneumoniae in 1 of 1 patient (100%) (3) Although one patient developed drug eruption, there were no side effects that necessitated cessation of administration" 09/01/2008 - "Fixed drug eruption caused by amoxicillin-clavulanic." 09/01/1997 - "On reviewing the literature we have only found three reports of fixed drug eruption fue to amoxycillin." 09/01/1997 - "We present a case of fixed drug eruption on the genital mucosa induced by amoxycillin" 09/01/1997 - "Fixed drug eruption from amoxycillin." Get all the results and reference details, order at left...
2.	AntibodiesIBA 10/01/1994 - "Based on these patients, the following should be noted: 1) drug eruption may occur in both types of rhG-CSF without detectable antibodies, 2) intradermal test is useful for determination of the causal drug, and 3) if one rhG-CSF product causes eruption, the alternative one may possibly be safe and effective." 01/01/1976 - "We speculate the antibodies are similar to those found in burns, drug eruptions and certain other skin diseases." Get all the results and reference details, order at left...
3.	cetuximab (Erbitux)FDA Link 07/01/2007 - "We conclude that triple therapy is an effective treatment for patients with severe acneiform drug eruptions caused by cetuximab." 07/01/2007 - "We report two patients with metastatic colorectal carcinoma, who developed a severe acneiform drug eruption on the face and upper part of the body during the treatment with cetuximab" 01/01/2007 - "Papulopustular drug eruption due to an epidermal growth factor receptor inhibitors, erlotinib and cetuximab." Get all the results and reference details, order at left...
4.	bosentan (Tracleer)FDA Link 01/01/2006 - "Drug eruption due to bosentan in a patient with systemic sclerosis." 11/01/2007 - "Oral administration of bosentan was effective in improving her dyspnea but had to be stopped because of drug eruption along with fever and eosinophilia" Get all the results and reference details, order at left...
5.	sephadexIBA 01/01/1978 - "Moreover, in fixed drug eruption, the addition of soluble skin material fractionated by gel filtration with Sephadex G-100 (FrD1) is as effective as the autologous sera in inducing lymphocyte transformation" Get all the results and reference details, order at left...
6.	hemodesIBA 03/01/1983 - "Efficacy of hemodes in combination with desensitizing drugs in dermatitis medicamentosa]" Get all the results and reference details, order at left...
7.	Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)FDA LinkGeneric 10/01/1999 - "The purpose of this study was to investigate the usefulness of topical provocation in the diagnosis of cotrimoxazole-induced fixed-drug eruption (FDE)" 07/01/2008 - "Cotrimoxazole was the most common cause of drug eruptions." 01/01/2008 - "We suggest that desensitization protocols with co-trimoxazole be considered in patients with fixed drug eruption, especially when there are no alternative drugs." 01/01/2008 - "We present the case of an 85-year-old woman with a fixed drug eruption to co-trimoxazole" 01/01/2008 - "Although co-trimoxazole is a major cause of fixed drug eruption, there are no reports in the literature of desensitization protocols for co-trimoxazole in such patients" Get all the results and reference details, order at left...
8.	Anti-Bacterial Agents (Antibiotics)IBA 06/01/2007 - "The objective of this review is to address patch testing for the evaluation of exanthematous drug eruptions due to systemic antibiotics, using a MEDLINE database search for articles in English on patch testing for systemic drug eruptions caused by antibiotics." 09/01/2004 - "Fixed drug eruption is an infrequent but well-known adverse event most commonly associated with antibiotics and nonsteroidal anti-inflammatory medications" 08/01/2004 - "We studied 28 patients with fixed drug eruption (FDE) caused by sulfonamide antibiotics to investigate cross-reactivity between sulfonamide derivatives and p-amino compounds and to explore the usefulness of patch testing, as an alternative to controlled oral challenge testing (COCT), in diagnosis within this clinical area" 02/01/2001 - "In some cases the drug eruptions exacerbate by re-administration of beta-lactam antibiotics" 05/01/2000 - "Localized forms of pustular drug eruptions related to antibiotics are uncommon and their mechanism is still unknown" Get all the results and reference details, order at left...
9.	Antipyrine (Phenazone)FDA LinkGeneric 06/01/1957 - "Dermatitis medicamentosa due to antipyrine; a study of twenty-eight cases in Negroes following the use of a proprietary medication (666 cold preparation)." 01/01/2006 - "A porcine model for fixed drug eruptions in humans: the case of antipyrine in the Yucatan micropig." 07/01/1996 - "Topical and systemic provocation of fixed drug eruption due to phenazone." 04/01/1972 - "Fixed drug eruption due to phenazone in a hypnotic." 02/01/1948 - "Fixed drug eruption due to antipyrine contained in kazefurusan; report of a case." Get all the results and reference details, order at left...
10.	Naproxen (Naprosyn)FDA LinkGeneric 07/01/2005 - "Neutrophilic fixed drug eruption caused by naproxen: a real entity or a stage in the histopathologic evolution of the disease?" 07/01/2004 - "Naproxen-induced generalized bullous fixed drug eruption." 03/01/1996 - "These findings suggested a fixed drug eruption (FDE) due to naproxen, a sporadic clinical event previously reported only once" 01/01/1987 - "Fixed drug eruption due to naproxen." 07/01/2004 - "The aim of this study was to investigate the usefulness of topical provocation in the diagnosis of metamizol- and naproxen-induced fixed drug eruption (FDE)" Get all the results and reference details, order at left...
442 Drugs and Important Bio-Agents and 687 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Transplants (Transplant) 01/01/1994 - "Immunohistochemical study of graft-versus-host reaction (GVHR)-type drug eruptions." 03/01/1969 - "Fixed drug eruption: an autoradiographic study of exchange grafts." 01/01/1994 - "Skin biopsies of graft-versus-host reaction (GVHR)-type drug eruptions in the acute phase were compared immunohistochemically with those in the chronic phase and also with non-GVHR type drug eruptions in the acute phase" 08/06/1999 - "In these diseases, or some other conditions occasionally distributed along these lines (chronic graft versus host reaction, fixed drug eruption, lupus erythematosus, atopic dermatitis, etc.), the cause of the disease may lead to the unmasking of tolerance to an abnormal keratinocyte clone that remained hidden in these lines" 03/01/1990 - "It has been reported that cutaneous SH-induced drug eruptions have a wide variety of clinical presentations; histologically, they show a pattern of eosinophilic necrosis and/or satellite necrosis similar to that seen in cutaneous graft vs host reactions" Get all the results and reference details, order at left...
2.	Self Medication 07/01/2008 - "AIMS: The present study was carried out to determine the age, sex incidence and clinical pattern of drug eruptions, to recognize offending drugs (self medication or prescribed), to evaluate mortality and morbidity associated with drugs, to educate the patients, and to avoid self-administration of drugs and re-administration of the offending drugs" 04/01/2004 - "CASE REPORTS: All the patients presented one or more fixed drug eruption reactivation lesions induced by sulfaguanidine as self-medication for diarrhea" Get all the results and reference details, order at left...
3.	Self Administration (Administration, Self) 07/01/2008 - "AIMS: The present study was carried out to determine the age, sex incidence and clinical pattern of drug eruptions, to recognize offending drugs (self medication or prescribed), to evaluate mortality and morbidity associated with drugs, to educate the patients, and to avoid self-administration of drugs and re-administration of the offending drugs" Get all the results and reference details, order at left...
4.	Drug Therapy (Chemotherapy) 08/01/2008 - "Drug eruptions are common adverse reactions to drug therapy and are a frequent reason for consultation in clinical practice" 01/01/2003 - "Cutaneous drug eruptions are among the most common adverse reactions to drug therapy" 08/01/1987 - "Seven patients receiving systemic chemotherapy for solid tumors developed an erythematous papulosquamous eruption resembling a drug eruption in sun-exposed areas" 09/01/1988 - "Drug eruptions occurred in 22 patients; 2 died of Stevens-Johnson syndrome subsequent to drug therapy for tuberculosis" 12/01/2004 - "Chemotherapy- related side effect, such as grade I-II nausea (n=2), grade II vomiting (n=1), fever (n=1), drug eruption (n=1) and catheter-related complication such as dislodgement of the catheter (n=2), occurred in six patients" Get all the results and reference details, order at left...
5.	Polypharmacy 07/01/2003 - "The measures for the drug profiles were medicine type (ATC-code), mono- and polypharmacy, CYP-enzyme metabolism pattern, and medicine with a potential to induce lichenoid drug eruptions" 01/01/2003 - "Drug eruptions are particularly common in patients who are HIV positive, presumably as a result of immune dysregulation, altered drug metabolism, and polypharmacy" Get all the results and reference details, order at left...
18 Therapies and Procedures and 28 more articles analyzed in the Research Interface, order at left...

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