|1.||Bipolar Disorder (Mania)
|2.||Mood Disorders (Mood Disorder)
|3.||Major Depressive Disorder (Major Depressive Disorders)
|4.||Panic Disorder (Panic Attack)
|5.||Schizophrenia (Dementia Praecox)
|1.||Gałecki, Piotr: 21 articles (01/2015 - 12/2004)|
|2.||Krupina, N A: 16 articles (07/2015 - 02/2000)|
|3.||Szemraj, Janusz: 13 articles (01/2015 - 01/2009)|
|4.||Khlebnikova, N N: 12 articles (07/2015 - 06/2002)|
|5.||Maes, Michael: 12 articles (12/2014 - 02/2005)|
|6.||Thase, Michael E: 12 articles (01/2014 - 06/2002)|
|7.||Dudek, Dominika: 11 articles (01/2016 - 11/2002)|
|8.||Orlova, I N: 11 articles (07/2015 - 02/2000)|
|9.||Talarowska, Monika: 11 articles (01/2015 - 07/2011)|
|10.||Florkowski, Antoni: 11 articles (01/2013 - 12/2004)|
|1.||Antidepressive Agents (Antidepressants)IBA
08/01/1981 - "Antidepressant drugs have been most specifically beneficial for patients with 'endogenous' depressions, but they should be used whenever this type of depression cannot be definitely ruled out. "
11/01/1995 - "In conclusion, the evaluation of risk-benefit ratio associated with antidepressants, drugs of proven efficacy in many indications, should take into account the risks of not treated depressive disorders (chronicity, social functioning and mortality)."
09/01/2009 - "Although depressive disorders affect approximately 5% of the population in developed countries each year, current antidepressants usually require several weeks to produce beneficial clinical effects and are only effective in about 55% of patients. "
06/01/2007 - "The delayed onset of therapeutic response and the high number of nonresponders to antidepressants remain major clinical problems in depressive disorders. "
01/01/2007 - "Firstly, new antidepressant drugs such as SSRIs and SNRIs are very useful to treat depressive disorders without severe adverse effects, which might lead to a good rate of adherance to the drugs. "
03/01/2002 - "Lithium also may be beneficial in recurrent unipolar depression and is an effective adjunct for treatment-resistant depression. "
11/01/1990 - "The results support the view that the everyday clinical use of lithium as prophylaxis is beneficial in unipolar depression."
08/01/1988 - "Lithium noncompliance is a significant barrier to effective treatment of manic-depressive disorders, yet the reasons for it are not well established. "
05/01/1985 - "A significant reduction was found on all indices during lithium management as compared to before lithium treatment, attesting to the efficacy of long-term prophylactic lithium in recurrent unipolar depression. "
06/01/1979 - "We concluded that ECT followed by either lithium or a tricyclic antidepressant is a more effective treatment for unipolar depression than ECT alone."
|3.||venlafaxine (Effexor)FDA LinkGeneric
04/01/2006 - "Venlafaxine ER was shown to be an effective and safe drug for the treatment of very elderly primary care patients with depressive syndrome and associated anxiety symptoms."
05/01/2009 - "The results achieved show that treatment with venlafaxine extended release significantly improved the clinical condition of climacteric patients with anxiety or depressive disorder. "
01/01/1997 - "Venlafaxine was effective in outpatients and hospitalized patients with major depression and in those with melancholia, agitated or retarded symptoms, and refractory or treatment-resistant depression. "
01/01/1997 - "Venlafaxine is effective in a broad spectrum of patients, including outpatients and inpatients, those with and without melancholia, patients with symptoms of anxiety or agitation or retardation and patients with first time or recurrent episodes of major depression. "
11/01/2014 - "The aim of this study was to assess whether the combination of low frequency repetitive transcranial magnetic stimulation (rTMS) and venlafaxine (150-225 mg/day) is effective and safe for treatment-resistant unipolar depression (TRD). "
|4.||Imipramine (Janimine)FDA LinkGeneric
12/01/1975 - "Two of the three trials of imipramine in neurotic depression gave results showing significant improvement. "
07/01/1992 - "After six weeks of treatment the results showed that the scores on the Hamilton Depression Scale as well as on the Melancholia Scale were significantly more improved in the imipramine-plus-minaserin group than in the group of patients receiving imipramine alone (P less than 0.01). "
05/01/1999 - "Imipramine was more effective against the clusters related to core symptoms of depression: "depression and guilt", "retardation", and "melancholia", respectively. "
04/01/1994 - "The authors' first objective was to ascertain whether imipramine is superior to placebo in treating axis I depressive disorders in the context of HIV illness. "
04/01/1993 - "Alternatively, if cognitive therapy and imipramine are effective for different subtypes of depressive disorder, then imipramine ought to be more effective than placebo for patients failing to benefit from cognitive therapy because some potential imipramine failures would already have been removed. "
|5.||Citalopram (Escitalopram)FDA Link
01/01/1985 - "The relationship between improvement (percentage reduction in total score on the Montgomery-Asberg Depression Rating Scale) and serum level of citalopram indicated a lower limit of effect in endogenous depression at about 100 nM, corresponding to an average dose of 15 mg. Marked improvement was seen in ten patients with steady state levels in the range 70 to 335 nM. The ten nonendogenously depressed patients had steady state levels from 15 to 620 nM; complete remission was seen in the three with the lowest levels (15-25 nM). "
01/01/1999 - "The results of this study indicate that citalopram is safe and effective in the treatment of depressed patients with melancholia, and is associated with a favorable side effect profile and a potentially rapid onset of action."
05/01/2015 - "Following escitalopram treatment, improvement in apathy significantly correlated with improvement in disability measures, while change in the rest of the depressive syndrome did not. "
12/01/1999 - "Citalopram was significantly more effective than placebo in the treatment of moderate-to-severe major depression, especially symptoms of depressed mood and melancholia, with particularly robust effects shown at doses of 40 and 60 mg/day. "
12/01/1999 - "Patients randomly assigned to 40 mg/day and 60 mg/day of citalopram showed significantly greater improvement than placebo on all efficacy measures, as well as on the HAM-D symptom clusters measuring depressed mood, melancholia, cognitive disturbance, and psychomotor retardation. "
|6.||Fluoxetine (Prozac)FDA LinkGeneric
11/01/2011 - "The improvement in cellular oxidative status may be an important mechanism underlying the protective pharmacological effects of fluoxetine, which are clinically observed in the treatment of depressive disorders."
01/01/1993 - "Fluoxetine was statistically significantly superior to placebo in patients with melancholia (endpoint change in the Montgomery-Asberg Depression Rating Scale [MADRS] score, response rates and remission rates). "
01/01/2008 - "Acupuncture is an effective and safe therapy for depressive neurosis; therapeutic effect of acupuncture on depressive neurosis possibly is better than or similar to that of Prozac, but with less side-effects."
04/18/2002 - "By contrast, in only one placebo-controlled study fluoxetine (SSRI) has shown to be effective in the treatment of depressive disorders in these age groups. "
03/01/2000 - "To get an impression of the efficacy of the widely used phytopharmaceutical St. John's wort, the antidepressant efficacy in mild depressive disorders was compared with that of the standard antidepressant fluoxetine. "
|7.||Serotonin (5 Hydroxytryptamine)IBA
12/01/1987 - "The very marked decrease in plasma 5-HT levels may be in accord with the central nervous system changes reported in depression and suggests the possibility of using plasma 5-HT as a peripheral indicator of abnormal serotonin function in melancholia."
01/01/1990 - "This review provides an update on the efficacy of serotonin-specific drugs for anxiety and depressive disorders."
01/01/2010 - "Pharmacological and genetic studies in humans and experimental animals have shown that 5-HT is important for the pathophysiology of depressive disorders. "
09/01/2003 - "This review will follow the evolution of serotonin receptor and transporter studies in postmortem tissues that initially focused on suicide and gradually incorporated depressive disorders as psychiatric assessments were increasingly performed. "
01/01/1996 - "[A clinico-biological study of the thrombocyte serotonin-transport complex in therapeutically resistant patients with endogenous depression undergoing combined treatment]."
|8.||Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
09/01/2005 - "If a depressive disorder is also present, or if obsessive thoughts are predominant, a combination of cognitive behavioral therapy and pharmacological treatment with (selective) serotonin reuptake inhibitors has proven effective."
08/01/2003 - "Previous studies suggest that selective serotonin reuptake inhibitors (SSRIs) are effective when used alone in the treatment of unipolar depression with psychotic features. "
01/01/2012 - "Selective Serotonin Reuptake Inhibitors (SSRI) are an effective treatment for depressive disorder. "
01/01/2008 - "To evaluate the efficacy of selective serotonin reuptake inhibitors (SSRIs) in children and adolescents with depressive disorder, the main electronic databases and the reference lists of retrieved articles and reviews were searched up to January 2007. "
11/01/2012 - "The quality of studies regarding the psychopharmacological therapy of depressive disorders in childhood and adolescence has improved since the «black box» warning of the FDA concerning the occurrence of suicidality under treatment with selective serotonin reuptake inhibitors (SSRIs). "
|9.||Amitriptyline (Elavil)FDA LinkGeneric
12/01/1998 - "The results from both studies showed that the therapeutic efficacy of EA was equal to that of amitriptyline for depressive disorders (P > 0.05). "
11/01/1995 - "This report describes a case of encephalopathy developed in the course of amitriptyline therapy, during a remission of unipolar depression. "
01/01/1994 - "The aim of this study was to compare the therapeutic and side effects with doses and plasma concentrations in the patients with major (unipolar) depression (DSM-III-R criteria) treated by amitriptyline combine (At+Li) and mono-therapy. "
03/01/1993 - "The present study used two different methods to define treatment outcome profiles--rationally-derived criteria (Frank et al., Archives of General Psychiatry 48, 851-855, 1991) and dynamic clustering--to evaluate four treatments of unipolar depression: behaviour therapy, amitriptyline, psychodynamic psychotherapy and relaxation training (attention placebo). "
02/01/2005 - "Fifty Caucasian inpatients with at least medium-grade depressive disorder received amitriptyline at a fixed dose of 75 mg twice a day. "
|10.||Sertraline (Zoloft)FDA LinkGeneric
05/01/2001 - "As a result of its proven efficacy, good tolerability and lack of pharmacokinetic interactions, sertraline should be considered first-line in the treatment of anxiety and depressive disorders."
01/01/2011 - "Within a randomized placebo-controlled single-centre 10-week trial with 5 arms (sertraline; placebo; cognitive-behavioral group therapy, CBT-G; moderated self-help group control; treatment with sertraline or CBT-G according to patients' choice), outcomes for 145 primary care patients with mild-to-moderate depressive disorders according to DSM-IV criteria were investigated. "
01/02/2015 - "Seventy-three patients with moderate-to-severe, antidepressant-free unipolar depression were assigned to a pharmacological (sertraline) and a non-pharmacological (transcranial direct current stimulation, tDCS) intervention in a randomized, 2 × 2, placebo-controlled design. "
01/01/2011 - "Eligibility criteria are moderate-to-severe unipolar depression (Hamilton Depression Rating Scale >17) not currently on sertraline treatment. "
06/01/2010 - "Regarding suicidality, this audit in a small group of patients suggests that sertraline is the most effective antidepressant monotherapy in reducing suicidality in patients with unipolar depression. "
|1.||Drug Therapy (Chemotherapy)
09/01/2000 - "Both psychotherapy and pharmacotherapy have been found to be beneficial for the acute treatment of children and adolescents with depressive disorders. "
10/01/1998 - "Both psychotherapy and pharmacotherapy have been found to be beneficial for the acute treatment of youth with depressive disorders. "
11/01/2014 - "It was recognized that herbal anti-depressant formulations made from SJW are at least as effective for the treatment of unipolar depression in old age as classical pharmacotherapy, while having fewer side effects (Cochrane reports, 2008). "
01/01/1997 - "A single randomized controlled clinical trial, and additional anecdotal evidence, suggests that antidepressant pharmacotherapy is effective for depressive disorders in MS. Future epidemiological studies should not restrict their evaluation of risk factors to those specific factors that are closely related to the disease process. "
04/10/1965 - "THREE THERAPEUTIC MODALITIES HAVE PROVED EFFECTIVE IN THE TREATMENT OF DEPRESSIVE SYNDROMES: electroconvulsive therapy (ECT), pharmacotherapy and psychotherapy. "
09/01/2002 - "In Study 2 this process was repeated in a group of 27 subjects who were in remission from unipolar depression after treatment with psychotherapy and who completed SRM-17 for at least 20 successive weeks. "
06/01/2010 - "We also decided to compare the efficacy of 'the four' versus 'the others' in patients with unipolar depression in Bedford East CMHT, using discharge rates and rates of reduced suicidality (including suicidal ideation and Behaviour) after treatment by the CMHT as the outcome measures. "
06/01/2010 - "We intended to compare the efficacy of antidepressant monotherapies in patients with unipolar depression at Bedford East CMHT, using discharge rates and rates of reduced suicidality (including suicidal ideation and Behaviour) after treatment by the CMHT as the outcome measure. "
03/01/2015 - "The effect of acupuncture on early onset of SSRls in treating acute phase depressive disorder pa- tients was evaluated by HAMD score in the control group and the treatment group before treatment,and at weekends of the 1st, 2nd, and 4th week after treatment. "
04/03/2014 - "Observation of decreased phosphorylation of GSK3β in platelets of both AD patients with depressive symptoms and depressive patients after treatment confirms the role of increased GSK3β activity in the pathophysiology of both AD and depressive disorder. "
|3.||Activities of Daily Living (ADL)
07/01/2001 - "Patients whose depressive disorder remitted at follow-up had significantly greater recovery in ADL functions compared with patients whose depression did not remit. "
04/01/2015 - "Activity of daily living was assessed with the Instrumental Activities of Daily Living Scale (IADL), life events were evaluated with the Life Event Scale, depressive disorders were diagnosed using the Geriatric Depression Scale (GDS), and QOL was measured using the Medical Outcomes Study Short Form-12 (SF-12) and St. George's Respiratory Questionnaire (SGRQ). "
01/01/2015 - "Patients receiving pharmacological treatment for depression or other illnesses were included. Types of intervention(s)/phenomena of interest: This review considered studies that used nonpharmacological interventions for older adults with depressive disorders. Types of studies: This review considered any experimental study design, including randomized controlled trials, non-randomized controlled trials, or other quasi-experimental studies, including before and after studies. Types of outcomes: This review considered studies that included the following outcome measures: depressive symptomatology. The secondary outcomes were the level of autonomy in activities of daily living, cognitive function, health-related quality of life and wellbeing. "
04/04/2006 - "One year after a baseline evaluation, data were collected by using the following tools: Hamilton Depression Rating Scale, the depressive disorders section of the Structured Clinical Interview for DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, fourth edition), Charlson Comorbidity Index, Multilevel Assessment Instrument for measuring instrumental activities of daily living, Physical Component Summary of the Medical Outcomes Study Short Form-36, and Duke Social Support Index. "
07/01/2015 - "We aimed to determine the prevalence of neurocognitive impairment using the IHDS and depressive disorders using the Hamilton Rating Scale for Depression (HAM-D17), compare the IHDS performance with the performances on the Timed Gait Test (TGT), the Digit Symbol Coding Test (DS) and the Brazilian version of the Scale of Instrumental Activities of Daily Living (IADL), and evaluate the association between the IHDS performance and clinical-demographic variables. "
|4.||Phototherapy (Light Therapy)
01/01/2012 - "The objective of the present clinical and psychopathological study was to estimate the influence of high-intensity white and yellow phototherapy on the clinical condition of 41 and 18 patients respectively presenting with astheno-depressive syndrome. "
11/01/2012 - "Phototherapy is used since early of 1980 years as non-drug method of therapy for seasonal depressive disorders. "
05/01/2012 - "Light Therapy (LT) when combined with standard antidepressant treatment for unipolar depression hastens recovery. "
03/01/2004 - "The response rate to 1-week light therapy and relapse during the continuation phase of 15 weeks were assessed by use of the Hamilton Depression Rating Scale (HAM-D17), the six-item subscale (HAM-D6), the Melancholia Scale (MES), and the combined HAM-D/SIGH-SAD. "
01/01/1997 - "Light therapy for depressive disorders: indications and efficacy."
03/01/2015 - "Randomized controlled trials of techniques meeting the Agency for Healthcare Research and Quality definition of meditation, for participants having clinically diagnosed depressive disorders, not currently in remission, were selected. "
03/01/2015 - "Critical analysis of the efficacy of meditation therapies for acute and subacute phase treatment of depressive disorders: a systematic review."
04/15/2010 - "Mindful meditation and exercise have positive effects as adjunctive treatments for depressive disorders, although some studies show multiple methodological weaknesses. "
03/01/2015 - "A substantial body of evidence indicates that meditation therapies may have salutary effects on patients having clinical depressive disorders during the acute and subacute phases of treatment. "
11/01/2011 - "This paper presents a case study in which Theravadan Buddhist mindfulness meditation and cognitive therapy practices were used in the treatment of a client with depressive disorder. "