A nucleoside consisting of the base guanine and the sugar deoxyribose.
Also Known As:
Guanosine, 2'-deoxy-
Networked: 132 relevant articles (3 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Zhang, Junfeng: 2 articles (05/2014 - 02/2013)
2. Lu, Shou-En: 2 articles (05/2014 - 02/2013)
3. Ohman-Strickland, Pamela: 2 articles (05/2014 - 02/2013)
4. Wang, Yuedan: 2 articles (05/2014 - 02/2013)
5. Kipen, Howard: 2 articles (05/2014 - 02/2013)
6. Hu, Min: 2 articles (05/2014 - 02/2013)
7. Zhu, Tong: 2 articles (05/2014 - 02/2013)
8. Zhu, Ping: 2 articles (05/2014 - 02/2013)
9. Wang, Guangfa: 2 articles (05/2014 - 02/2013)
10. Huang, Wei: 2 articles (05/2014 - 02/2013)

Related Diseases

1. Inflammation
12/01/2015 - "8-Hydroxy deoxyguanosine (8-OHdG) is a marker of this process and its levels in saliva could be linked to the severity of periodontal inflammation. "
11/01/2015 - "Plasma concentrations of Hcy and both plasma and CSF levels of folate, Cbl, nicotinamide adenine dinucleotide (NAD(H)) and markers of inflammation (interleukin-6, IL-6), and oxidative stress (F2-isoprostanes, 8-hydroxy-2'-deoxyguanosine (8-OHdG), and total antioxidant capacity (TAC)) were quantified. "
01/13/2012 - "Inflammation generates lipid peroxidation (LPO) products which can react with deoxycytidine, deoxyadenosine, and deoxyguanosine in DNA to form pro-mutagenic exocyclic etheno-nucleoside residues. "
03/01/2013 - "Markers of oxidative stress [malondialdehyde (MDA), advanced glycation end products (AGEs), thiols, advanced oxidation protein products and 8-hydroxy-2'-deoxyguanosine] and markers of inflammation (C-reactive protein, interleukin-6 and tumour necrosis factor alpha) were also measured. "
02/01/2013 - "Using the combination of a quasi-experimental design and a panel-study approach, we measured biomarkers of autonomic dysfunction (heart rate [HR*] and heart rate variability [HRV]), of systemic inflammation and oxidative stress (plasma C-reactive protein [CRP], fibrinogen, blood cell counts and differentials, and urinary 8-hydroxy-2'-deoxyguanosine [8-OHdG]), of pulmonary inflammation and oxidative stress (fractional exhaled nitric oxide [FeNO], exhaled breath condensate [EBC] pH, EBC nitrate, EBC nitrite, EBC nitrite+nitrate [sum of the concentrations of nitrite and nitrate], and EBC 8-isoprostane), of hemostasis (platelet activation [plasma sCD62P and sCD40L], platelet aggregation, and von Willebrand factor [vWF]), and of blood pressure (systolic blood pressure [SBP] and diastolic blood pressure [DBP]). "
2. Communicable Diseases (Infectious Diseases)
3. Bone Marrow Diseases (Bone Marrow Disease)
4. Neoplasms (Cancer)
5. Anoxia (Hypoxia)
08/15/2009 - "Indirect markers of oxidative stress (oxidized nucleic acid 8-hydroxy-2'-deoxyguanosine, redox-sensitive transcription factor c-fos, and hypoxia-inducible factor-1alpha) were increased after social isolation in brain areas with high NOX2 expression. "
11/01/1994 - "However, the cell cycle inhibition induced under moderate hypoxia is partially reversed in the presence of exogenously added deoxycytidine and uridine, while no such reversal is seen in the presence of purine deoxynucleosides (deoxyadenosine and deoxyguanosine). "
05/01/1992 - "To correlate the reduction of cell growth under hypoxia with the functional pyrimidine supply, hypoxic cells were cultured in the presence of a balanced mixture of deoxynucleosides and/or uridine (100 microM deoxycytidine, 10 microM deoxyadenosine, 10 microM deoxyguanosine, 100 microM uridine). "
03/01/2013 - "The objective of this study is to explore the protective effect of an angiotensin receptor blocker (ARB) on local cardiovascular angiotensin II (AngII) and oxidative stress markers such as malondialdehyde (MDA), NADPH oxydase p47(phox), and 8-hydroxy-2'-deoxyguanosine/8-hydroxyguanosine (8-OHdG/8-OHG) of mice that had chronic intermittent hypoxia (CIH). "
03/01/1987 - "Supplementation of cells cultured under hypoxia with a combination of deoxynucleosides (100 microM deoxycytidine, 10 microM deoxyadenosine, 10 microM deoxyguanosine) was found to stimulate reprogression through the cycle, provided the residual oxygen tension in the protective atmosphere exceeded 40 ppm. The increase in the number of cells with a DNA content of more than 4 C and in the number of binucleate cells observed after re-aeration of hypoxic cells was not prevented by deoxynucleosides or by uridine, which were present in the medium either during hypoxia of from the beginning of reoxygenation. "

Related Drugs and Biologics

1. Biological Markers (Surrogate Marker)
2. DNA Adducts
3. C-Reactive Protein
4. Nitric Oxide (Nitrogen Monoxide)
5. Oligonucleotides
6. Autoantibodies
7. CPG-oligonucleotide
8. oxidized low density lipoprotein
9. F2-Isoprostanes (F2 Isoprostanes)
10. Vitamins

Related Therapies and Procedures

1. Transplants (Transplant)
2. Resuscitation
3. Radiotherapy
4. Intravenous Injections
5. Drug Therapy (Chemotherapy)