|1.||Russell, Paul: 1 article (11/2012)|
|2.||Chabes, Andrei: 1 article (11/2012)|
|3.||Roguev, Assen: 1 article (11/2012)|
|4.||Rozenzhak, Sophie: 1 article (11/2012)|
|5.||Sánchez, Arancha: 1 article (11/2012)|
|6.||Krogan, Nevan J: 1 article (11/2012)|
|7.||Sharma, Sushma: 1 article (11/2012)|
|8.||Neyts, Johan: 1 article (10/2008)|
|9.||Andrei, Graciela: 1 article (10/2008)|
|10.||De Clercq, Erik: 1 article (10/2008)|
01/01/1990 - "Deoxycytidylate aminohydrolase activity in the Novikoff hepatoma is dependent on the localization of the tumor."
11/01/2001 - "The great majority of head-and-neck tumors from patient material had markedly higher levels of dC kinase and dCMP deaminase than found in adjacent normal tissue. "
05/01/1987 - "H4Urd treatment of 25 mg/kg did not affect the elevated levels of deoxycytidine kinase or deoxycytidylate deaminase in LLC tumor tissue or the low levels found in normal tissue. "
01/01/1990 - "Evidence is presented which indicates that deoxycytidylate aminohydrolase activity, and the expression of alternate pathways of pyrimidine biosynthesis in the Novikoff hepatoma, is dependent on the localization of the tumor within the host."
01/01/1990 - "The activity of deoxycytidylate aminohydrolase, a pivotal enzyme for pyrimidine biosynthesis in mammalian tissue, is 100x greater in the Novikoff hepatoma harvested from the intraperitoneal cavity than in the same tumor excised from either subcutaneous or intramuscular sites. "
11/03/1992 - "Modulation of deoxycytidylate deaminase in intact human leukemia cells. "
01/01/1983 - "Deoxycytidylate deaminase has been highly purified (1232-fold) from human leukemia CCRF-CEM cells. "
09/15/1982 - "The therapeutic efficacy of combinations of fluorinated pyrimidines and inhibitors of either ribonucleotide reductase or deoxycytidylate deaminase was evaluated for the treatment of the L1210 mouse leukemia in DBA/2 mice. "
03/01/1972 - "Relationship between Escherichia coli B titer and the level of deoxycytidylate deaminase activity induced on bacteriophage T2r + infection."
04/28/2000 - "A deoxycytidylate (dCMP) deaminase encoded in T4-bacteriophage DNA that is induced on phage infection of Escherichia coli was shown earlier (Maley, G. "
02/05/1993 - "Deoxycytidylate (dCMP) deaminase, a hexameric allosteric enzyme induced on infection of Escherichia coli by bacteriophage T4, was shown to contain two atoms of zinc per subunit by atomic absorption spectroscopy. "
04/25/1987 - "Imbalanced deoxyribonucleoside triphosphate pools and spontaneous mutation rates determined during dCMP deaminase-defective bacteriophage T4 infections."
11/01/1974 - "The activities of dCMP deaminase and DNA polymerase I increased twofold and fivefold in BHK-21/C13 cells after infection by the virus of herpes simplex. "
|4.||Hepatocellular Carcinoma (Hepatoma)
01/01/1980 - "Correlation of deoxycytidylate deaminase activity with cell proliferation during hepatocarcinogenesis and tumour growth in transplantable rat hepatomas."
06/01/1977 - "It is concluded that the Dunning hepatoma probably has intrinsically low deoxycytidylate deaminase activity."
06/01/1977 - "Dunning hepatoma has a low activity of deoxycytidylate deaminase, comparable to that of normal adult rat liver. "
06/01/1977 - "Factors affecting deoxycytidylate deaminase activity in some transplantable rat hepatomas."
06/01/1977 - "Factors which might affect the activity of deoxycytidylate deaminase in the Dunning hepatoma have been examined in it and compared to the Novikoff hepatoma which has high activity of this enzyme. "
01/01/1979 - "The estimation of the enzyme activity of DCMP-Deaminase in the plasma seems to be a valuable method for the registration of pregnant woman with classical EPH-Gestosis and chronic kidney diseases."
12/01/1977 - "Elevations of plasma urate and serum dCMP deaminase are therefore both early features of pre-eclampsia. "
12/01/1977 - "Serial antenatal observations for a mean period of 104 days (36-179 days) on 33 of the patients demonstrated that plasma urate and serum dCMP deaminase increased together as early changes in the development of pre-eclampsia. "
12/01/1977 - "Plasma urate and serum deoxycytidylate deaminase measurements for the early diagnosis of pre-eclampsia."
04/01/1982 - "The results confirm that elevated dCMP deaminase activity (greater than 4.8 units) is associated with the development of pre-eclampsia but not with essential hypertension in pregnancy; a high rising level can precede eclampsia. "
|3.||Ribonucleotide Reductases (Ribonucleotide Reductase)
|7.||DNA (Deoxyribonucleic Acid)
|2.||Drug Therapy (Chemotherapy)