Dementia (Dementias)

An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
Also Known As:
Dementias; Dementia, Familial; Amentia; Familial Dementia; Amentias; Dementias, Familial; Dementias, Senile Paranoid; Familial Dementias; Paranoid Dementia, Senile; Paranoid Dementias, Senile; Senile Paranoid Dementias; Senile Paranoid Dementia
Networked: 18504 relevant articles (895 outcomes, 3159 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Alzheimer Disease (Alzheimer's Disease)
2. Parkinson Disease (Parkinson's Disease)
3. Stroke (Strokes)
4. Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
5. Schizophrenia (Dementia Praecox)


1. Morris, John C: 70 articles (11/2015 - 07/2002)
2. Blennow, Kaj: 67 articles (12/2015 - 01/2002)
3. Aarsland, Dag: 66 articles (01/2016 - 04/2004)
4. Ballard, Clive: 62 articles (12/2015 - 02/2002)
5. Mitchell, Susan L: 61 articles (12/2015 - 01/2003)
6. Trojanowski, John Q: 59 articles (11/2015 - 05/2002)
7. van der Steen, Jenny T: 55 articles (01/2016 - 03/2002)
8. Masliah, Eliezer: 55 articles (11/2015 - 01/2004)
9. Engedal, Knut: 54 articles (04/2015 - 02/2002)
10. Alzheimer's Disease Neuroimaging Initiative: 52 articles (01/2016 - 11/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dementia:
1. Memantine (Namenda)FDA Link
2. Antipsychotic Agents (Antipsychotics)IBA
3. donepezil (Aricept)FDA LinkGeneric
4. rivastigmine (Exelon)FDA LinkGeneric
5. Cholinesterase Inhibitors (Anticholinesterases)IBA
6. Risperidone (Risperdal Consta)FDA LinkGeneric
7. Biological Markers (Surrogate Marker)IBA
8. Amyloid (Amyloid Fibrils)IBA
9. Ginkgo biloba extract 761 (Rokan)IBA
10. Estrogens (Estrogen)FDA Link

Therapies and Procedures

1. Home Nursing (Nursing, Home)
08/01/2015 - "The RCS predicted dementia and MCI in study 2. The 3-item RCS exhibits good sensitivity and specificity for the detection of MCI and dementia, and higher cognitive function on the RCS is protective against nursing home placement and mortality. "
01/01/2015 - "The results from our study indicate that a high intensity functional exercise program improved balance and muscle strength as well as reduced apathy in nursing home patients with dementia. "
12/01/2005 - "Residents who died during the 2-year study period had significantly greater mean rates of utilization of all types of health care than residents who were not discharged from the nursing home, even when controlling for dementia diagnosis, age, functional status, and number of comorbid conditions. "
06/01/2012 - "The environmental dimensions of "maximizing awareness and orientation" and better "quality of stimulation" were associated specifically with reduced hazard of walking disability, whereas the dimensions of the nursing home environment specifically associated with a reduced hazard of eating disability included improved "safety and security," "opportunities for personal control," and "regulation of stimulation." The Cox proportional hazards models using the 13-point PEAP scale were not significantly different from nested models using the 5-point PEAP scale, indicating that the 2 scales did not differ in their ability to discriminate between more and less supportive environments for residents with dementia. "
12/01/2011 - "Findings suggest that soothing music may be beneficial in managing agitation in nursing home residents with dementia."
2. Activities of Daily Living (ADL)
3. Music Therapy
4. Drug Therapy (Chemotherapy)
5. Aftercare (After-Treatment)