|1.||Hearing Loss (Hearing Impairment)
|3.||Deafness (Deaf Mutism)
|4.||Vertigo (Positional Vertigo)
|5.||Bilateral Hearing Loss
|1.||Guan, Min-Xin: 43 articles (03/2015 - 07/2002)|
|2.||Friedman, Thomas B: 26 articles (03/2015 - 05/2003)|
|3.||Petit, Christine: 24 articles (11/2015 - 04/2002)|
|4.||Li, Ronghua: 19 articles (03/2015 - 07/2002)|
|5.||Dai, Pu: 19 articles (01/2015 - 02/2006)|
|6.||Avraham, Karen B: 19 articles (09/2014 - 03/2002)|
|7.||Riazuddin, Saima: 18 articles (03/2015 - 05/2003)|
|8.||Riazuddin, Sheikh: 18 articles (03/2015 - 05/2003)|
|9.||Ahmed, Zubair M: 18 articles (03/2015 - 05/2003)|
|10.||Zhu, Yi: 18 articles (06/2013 - 06/2005)|
|1.||Silver Sulfadiazine (SSD)FDA LinkGeneric
07/01/2014 - "Studies that investigate the subjective benefit from a bone conduction implant (BCI) sound processor in patients with single-sided sensorineural deafness (SSD) have been limited to examining short- and mid-term benefit. "
12/01/2012 - "To determine factors predicting whether patients with single-sided deafness (SSD) opt for a bone conduction device (BCD) for the contralateral routing of sound (CROS) after a regular trial with a BCD on a headband. "
04/01/2012 - "The purpose of this study was to present objective and subjective outcomes on speech-in-noise testing as a predictor of patient performance after bone-anchored implant surgery in patients with single-sided deafness (SSD). "
09/01/2015 - "To refine and extend the knowledge on cortical plasticity in single-sided deafness (SSD) by assessing magnetoencephalographic imaging in a well-defined group of subjects. "
08/01/2015 - "To analyze speech discrimination scores and subjective benefit of a transcutaneous bone conduction device (tBCD) in adults with single-sided deafness (SSD). "
|2.||Dexamethasone (Maxidex)FDA LinkGeneric
11/15/2007 - "Dexamethasone therapy prevented deafness in patients with H. "
11/01/1998 - "When we controlled for the confounding factor, severity of illness (intubation), the incidence of any deafness and of any neurologic sequelae, including deafness, were no longer significantly different between children who did or did not receive dexamethasone. "
02/01/1995 - "The addition of dexamethasone to antibiotic therapy prevented the development of profound deafness. "
10/13/1988 - "We conclude that dexamethasone is beneficial in the treatment of infants and children with bacterial meningitis, particularly in preventing deafness."
10/09/2012 - "This study provides Class III evidence that adjuvant dexamethasone in adults with meningococcal meningitis does not increase negative outcomes such as deafness, death, or negative Glasgow Outcome Scale measures."
|3.||Thiamine (Aneurin)FDA Link
12/01/2006 - "Thiamine induces a remarkable hematological response and improvement in the diabetic control but has no effect on deafness."
05/01/2009 - "Thiamine may be effective in preventing deafness if started before two months. "
06/01/2012 - "Thiamine-responsive megaloblastic anaemia (TRMA), due to mutations in the thiamine transporter SLC19A2, is associated with the classical clinical triad of diabetes, deafness, and megaloblastic anaemia. "
01/01/2012 - "Thiamine-responsive megaloblastic anaemia (TRMA) syndrome is an example of a rare form of monogenic diabetes coexisting with anaemia and deafness. "
01/01/2011 - "Does early treatment prevent deafness in thiamine-responsive megaloblastic anaemia syndrome?"
|4.||Nerve Growth Factors (Neurotrophins)IBA
05/01/2007 - "In earlier animal studies it has been demonstrated that neurotrophic factors are effective to improve SGC survival after experimentally induced deafness. "
11/01/2005 - "Experimental studies have demonstrated that neurotrophic factors can prevent this degeneration in animal models of deafness, and can even provide functional benefits. "
11/28/1999 - "Studies in the cochlea now show that application of exogenous neurotrophic factors can enhance survival of spiral ganglion cells after deafness and induce regrowth of peripheral processes, perhaps by replacing lost endogenous factors. "
09/09/2015 - "Deafness-induced degeneration of these cells can be averted with neurotrophic factors. "
09/26/2014 - "Nucleofected fibroblasts may therefore represent a method for safe, long-term delivery of neurotrophins to the deafened cochlea to support SGN survival in deafness."
|5.||Adrenal Cortex Hormones (Corticosteroids)IBA
01/01/2015 - " corticosteroids reduced the risk of death (typical RR 0.46, 95% confidence interval (CI) 0.24 to 0.88; typical RD -0.19, 95% CI -0.33 to -0.04; NNTB = 6; two studies, 132 participants, very low-quality evidence) but did not have a significant effect on the number of infants with sensorineural deafness at two years (RR 1.80, 95% CI 0.18 to 18.21; RD 0.04, 95% CI -0.12 to 0.21; one study, 38 participants, low-quality evidence). "
07/01/2005 - "The treatment of acute deafness is based on a systemic application of corticosteroids. "
07/01/1995 - "In 3 patients that were diagnosed early and treatment with corticosteroids was initiated early, hearing could be stabilized, in the remaining patients total bilateral deafness could not be prevented. "
08/01/2006 - "The symptoms could be improved by systemic and local administration of corticosteroids and immunosuppressive therapy, however, progression of inner ear deafness could not be stopped in one patient and a cochlear implant was necessary."
10/01/2007 - "The combined therapy include high-dose corticosteroids and defibrinogenation therapy is effective for the patients with total deafness and severe all frequency hearing loss. "
05/01/2002 - "Finally, we have shown that interventions with antioxidants may also be effective in preventing pathophysiological changes of the auditory nerve following deafness. "
10/01/2003 - "Therefore, we evaluated the use of antioxidants for the adjunctive therapy of meningitis-associated deafness. "
01/01/2008 - "This study assesses the combined efficacy of two classes of agents found effective in preventing degeneration of the auditory nerve following deafness, neurotrophic factors, and antioxidants. "
05/01/2002 - "Protection and regrowth of the auditory nerve after deafness: neurotrophins, antioxidants and depolarization are effective in vivo."
09/01/2010 - "Thresholds for electrically-evoked auditory brain stem responses (eABRs) were significantly elevated at 3 weeks with deafness, stabilized with GDNF, and showed no change with GDNF cessation and treatment with antioxidants or saline. "
|7.||Penicillins (Penicillin)FDA Link
06/20/1987 - "Penicillin overdose and deafness."
02/15/1986 - "Deafness after penicillin overdose."
07/01/2002 - "In the penicillin group 87.1% recovered uneventfully, 6.4% died, 2.1% developed blindness and 1.5% partial deafness. "
07/01/2002 - "In the penicillin group 87.1% recovered uneventfully, 6.4% died, 2.1% developed blindness and 1.5% partial deafness. "
03/01/1948 - "Penicillin treatment of nerve deafness due to syphilis."
|8.||Vasodilator Agents (Vasodilators)IBA
09/01/1959 - "[Sudden unilateral deafness cured by vasodilators]."
01/01/1991 - "The authors report 75 cases (including 4 children) treated between 1983 and 1988 by normovolemic hemodilution, corticoids and vasodilators for deafness of various origins. "
03/01/1980 - "Because we had a similar case, injected 10 ml of Urografin (76%) intravenously in 130 patients with sensorineural deafness and tinnitus, which had not improved with previous treatment consisting of vasodilators and stellate ganglion blocks. "
11/01/2007 - "Mutations in the connexin 26 gene seem to be extremely common in non-syndromic hereditary deafness genesis, especially the 35delG, but there are still only a few studies that describe the audiometric characteristics of patients with these mutations. "
12/01/2005 - "Previous studies have shown that one of these genes, connexin 26 (GJB2), accounts for 30-60% of such deafness, but the relative contribution of the many other genes is not known, especially in the outbred UK population. "
08/01/2004 - "Our study conducted on 39 children with pre-lingual bilateral sensorineural autosomal recessive deafness showed as follows: (I) from a molecular perspective: an incidence of 41% in the cases studied of mutations in the encoding of the connexin 26 gene; a prevalence in our case study of the 35delG mutation (69%). "
09/01/2003 - "After taking into account other factors which are known to affect language development and speech perception in children with impaired hearing, no significant differences were found between the 15 children where connexin 26 was known to be the cause of deafness and the other 37 children in the study."
10/01/2001 - "[Study of a mutation in connexin 26 gene associated with congenital sensorineural deafness]."
|10.||DNA (Deoxyribonucleic Acid)IBA
01/02/2014 - "In this study, whole-exome sequencing was performed with genomic DNA from affected individuals from three large consanguineous families in which markers linked to DFNB86 segregate with profound deafness. "
02/01/2011 - "[Study on the causes of deafness in a consanguineous marriage family using DNA microarray]."
06/01/2006 - "This study demonstrates that buccal smears are an adequate, reliable source of genomic DNA providing material for genetic tests that can especially help to avoid drawing blood from very young children for the genetic screening of deafness."
01/01/2003 - "In this study, real-time polymerase chain reaction (PCR) was used to measure CMV DNA in clinical samples (including perilymph) collected from five patients with deafness. "
04/01/1996 - "We are creating a bank of EBV immortalized lymphoblast cells and extracted DNA taken from the blood of deaf children and their relatives, in order to study the molecular basis of hereditary deafness. "
02/01/2015 - "Cochlear implantation is rapidly gaining acceptance as the most effective treatment for adult patients with unilateral deafness. "
08/01/2004 - "Cochlear implantation was least effective when the preoperative audiological status of the better-hearing ear was good and the duration of profound deafness of the implanted ear was long. "
01/01/2011 - "The results in these patients suggest that cochlear implantation improves hearing abilities in people with single-sided deafness and is superior to the alternative treatment options. "
01/01/2006 - "A major source of controversy between Deaf people and those who support a "social/cultural" view of Deafness as "a life to be lived" and those who see deafness within a "medical model" as a "condition to be cured" has been over the cochlear implantation of young deaf children. "
01/01/1998 - "We concluded that the results of postlingual patients after cochlear implantation showed clear benefits of these devices in profound bilateral deafness, better results with the SPEAK coding strategy than with MPEAK and constant improvement in results, even after the first year of surgery."
|2.||Cochlear Implants (Cochlear Implant)
06/01/2012 - "Cochlear implants are the best treatment for congenital profound deafness. "
10/01/2012 - "Recent research in genetics indicates that the cause of deafness in individuals with Usher type 1 (USH1) could be beneficial for the outcome with cochlear implants (CI). "
01/01/2014 - "Since their introduction more than 30 years ago, cochlear implants have improved their performance to the extent that are now considered to be standard of care in the treatment of children with severe to profound deafness. "
01/01/2009 - "PCR has proved to be a very useful tool in order to investigate infectious causes of deafness even for more than one virus type at a time and in a limited quantity of sample, such as the small volume of endolabyrinthine liquid collected from children during cochlear implant surgery."
11/01/2012 - "The cochlear implant (CI) is the first effective treatment for deafness and severe losses in hearing. "
|3.||Hearing Aids (Hearing Aid)
08/01/1996 - "This study has shown that in this preselected group of children with persistent OME and the predominant symptom of deafness, a hearing aid was an effective treatment for their deafness with high acceptance and compliance."
04/01/2009 - "The aim was to examine short- and long-term efficacy of the bone-anchored hearing aid (BAHA) on adults with single-sided deafness. "
04/01/2009 - "Efficacy of the bone-anchored hearing aid for single-sided deafness."
03/01/2003 - "Because age at implantation negatively correlates with improved speech perception after implantation, congenitally affected children with profound deafness (if they cannot obtain enough benefit from hearing aids) should receive implants as early as possible."
09/01/2015 - "No factors that were evaluated in this study, including gender, age, etiology of deafness, duration of deafness, time between implant insertion, and the preoperative hearing aid status, were correlated with stability duration in either stability assessment method. "
03/01/2007 - "In agreement with the notion that EABR maturation follows an apex-to-base gradient as described for ABR, we observed that wave V latencies were longer for the basal than the apical end of the implant electrode array and remained so throughout the study period, whatever the time of onset of deafness. "
01/01/1980 - "[Trials of treatment of perceptive deafness by implantation of electrodes into the cochlea (author's transl)]."
03/01/2015 - "In postmeningitis deafness, initial choice of electrode array is of utmost importance. "
10/01/2014 - "Variables such as patient age, degree of residual hearing, insertion depth, insertion speed, duration of profound high frequency deafness and electrode design have been proposed. "
02/01/2014 - "Positive preconditions are short ipsilateral and short bilateral deafness periods and high number of auditory electrodes. "
|5.||Prostheses and Implants (Prosthesis)
01/01/1993 - "However it must be only applied to total deafness which fail to show an improvement with conventional acoustic prostheses. "
10/01/1973 - "A hearing prosthesis for severe perceptive deafness--experimental studies."
06/13/1953 - "[Radioelectricity in the study of deafness and electronic prosthesis]."
04/01/2015 - "Sound location modulation of electrocochleographic responses in chinchilla with single-sided deafness and fitted with an osseointegrated bone-conducting hearing prosthesis."
01/01/2001 - "Surgical option is promising in cases of severe deafness when our aim is to improve the enlargement and recognition of environmental sounds when an acoustic prosthesis is not employed. "