Cytochrome-c Peroxidase

A hemeprotein which catalyzes the oxidation of ferrocytochrome c to ferricytochrome c in the presence of hydrogen peroxide. EC 1.11.1.5.

Also Known As:

Cytochrome Peroxidase; Cytochrome c-551 Peroxidase; Cytochrome c 551 Peroxidase; Cytochrome c Peroxidase; Peroxidase, Cytochrome; Peroxidase, Cytochrome c-551; Peroxidase, Cytochrome-c; Ferrocytochrome c:hydrogen-peroxide oxidoreductase

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Peroxidases: 304
      - Cytochrome-c Peroxidase: 8
        cytochrome C553 peroxidase
        E coli YhjA protein
        porphyrin cytochrome c peroxidase

Experts

1.	Liu, Shaoyi: 2 articles (05/2014 - 07/2013)
2.	Seshan, Surya V: 2 articles (05/2014 - 07/2013)
3.	Soong, Yi: 2 articles (05/2014 - 07/2013)
4.	Szeto, Hazel H: 2 articles (05/2014 - 07/2013)
5.	Borsini, Alessandra: 1 article (01/2022)
6.	Huang, Fei: 1 article (01/2022)
7.	Pariante, Carmine M: 1 article (01/2022)
8.	Butler, Brian P: 1 article (12/2020)
9.	Bäumler, Andreas J: 1 article (12/2020)
10.	Jang, Kyung Ku: 1 article (12/2020)

Related Diseases

1.	Ischemia 05/01/2014 - "It was recently shown to inhibit cardiolipin peroxidation by cytochrome c peroxidase activity, and it has been shown to protect mitochondrial cristae in proximal tubular cells during ischemia, and accelerated ATP recovery upon reperfusion. " 07/01/2013 - "In addition, the SS-31/cardiolipin complex inhibited cytochrome c peroxidase activity, which catalyzes cardiolipin peroxidation and results in mitochondrial damage during ischemia, by protecting its heme iron. "
2.	Infections 01/01/2015 - "Firstly, a gene encoding Cytochrome c Peroxidase (CCP) chromogenic enzyme was inserted into a wild type PP01 phage genome to construct the recombinant PP01ccp phage that was used in the production of the chromogenic enzyme through specific infection into E. " 01/01/2015 - "brasiliensis yeast cells were also up-regulated during macrophage infection, including superoxide dismutases (SOD), thioredoxins (THX) and cytochrome c peroxidase (CCP). "
3.	Necrosis 01/01/2022 - "Findings show that UDCA reduces apoptosis, reactive oxygen species (ROS) and tumour necrosis factor (TNF)-α production in neurodegenerative models, and reduces nitric oxide (NO) and interleukin (IL)-1β production in neuropsychiatric models; GUDCA decreases lactate dehydrogenase, TNF-α and IL-1β production in neurological models, and also reduces cytochrome c peroxidase production in neurodegenerative models; TUDCA decreases apoptosis in neurological models, reduces ROS and IL-1β production in neurodegenerative models, and decreases apoptosis and TNF-α production, and increases glutathione production in neuropsychiatric models. "
4.	Hypersensitivity (Allergy) 06/01/2013 - "Knockout mutants affecting 130 highly-upregulated genes were tested for menadione sensitivity, which revealed that loss of the transcription factor siderophore regulation (SRE) (a transcriptional repressor for siderophore biosynthesis), catatase-3, cytochrome c peroxidase or superoxide dismutase 1 copper chaperone causes hypersensitivity to menadione. "
5.	Hyperplasia 12/09/2020 - "However, we find that prior to the development of colonic crypt hyperplasia, T3SS-mediated intimate attachment is not required for aerobic respiration but for hydrogen peroxide (H2O2) respiration using cytochrome c peroxidase (Ccp). "

Related Drugs and Biologics

1.	Cardiolipins (Cardiolipin)
2.	Vitamin K 3 (Menadione)
3.	Reactive Oxygen Species (Oxygen Radicals)
4.	Siderophores
5.	Transcription Factors (Transcription Factor)
6.	Thioredoxins
7.	Superoxides (Superoxide)
8.	Oxygen (Dioxygen)
9.	Oxidoreductases (Dehydrogenase)
10.	Nitric Oxide (Nitrogen Monoxide)