|1.||Taylor, Robert W: 13 articles (09/2014 - 02/2004)|
|2.||Zeviani, Massimo: 11 articles (12/2015 - 08/2002)|
|3.||Turnbull, Douglass M: 9 articles (02/2013 - 11/2002)|
|4.||Tachtsidis, Ilias: 8 articles (10/2014 - 03/2007)|
|5.||Avadhani, Narayan G: 7 articles (01/2013 - 03/2003)|
|6.||Levy, Richard J: 7 articles (03/2011 - 02/2004)|
|7.||Shoubridge, Eric A: 6 articles (03/2015 - 01/2003)|
|8.||Blakely, Emma L: 6 articles (02/2013 - 02/2008)|
|9.||Smith, Martin: 6 articles (01/2013 - 03/2007)|
|10.||Elwell, Clare E: 6 articles (01/2013 - 03/2007)|
11/01/2012 - "In OT-stimulated cells, phospho-Akt accumulates intracellularly close to the mitochondrial marker cytochrome c oxidase subunit 4. Functional analyses reveal the involvement of Akt/ERK1/2 pathways in cell proliferation, migration, and protection against the cytotoxic and apoptotic effects of hypoxia and serum deprivation. "
02/01/1994 - "Hypoxia completely relieved the cytochrome-c-oxidase deficit. "
06/30/1999 - "The aim of the present study was to compare the capacity of the oxidative metabolism (total activity of cytochrome c oxidase, COX) in the right and left ventricular myocardium of adult rats exposed to intermittent high altitude (IHA) hypoxia simulated in a barochamber (5,000 m, 8 h/day, 5 days/wk, for a total of 32 exposures). "
07/25/1997 - "This study sought to link the hypoxia-induced changes in cytochrome oxidase to the inhibition of respiration seen in intact cells. "
09/01/2015 - "Hypoxia induced an increase in the activity of cytochrome c oxidase only at 4590 m. "
|2.||Muscular Diseases (Myopathy)
03/01/1992 - "Morphological studies failed to show ragged-red fibers but there was lipid storage myopathy and decreased cytochrome c oxidase activity. "
01/01/1991 - "In the fatal infantile myopathy due to cytochrome c oxidase (COX) deficiency, an autosomal recessive condition, immunocytochemical studies have shown an isolated defect of subunit VIIa, which is 1 of the only 2 tissue-specific subunits of human COX. "
02/01/2001 - "Skeletal muscle showed severe degenerating myopathy found to be full of ragged-red fibers (RRFs), an increased number of lipid droplets, and severe cytochrome c oxidase (COX) deficiency. "
07/01/2000 - "Cytochrome c oxidase (COX) deficiency is an important cause of myopathy or encephalomyopathy. "
10/01/1999 - "A missense mutation of cytochrome oxidase subunit II causes defective assembly and myopathy."
04/01/2013 - "Polymyositis with cytochrome C oxidase negative fibers--a pathological and clinical challenge."
01/01/1997 - "We evaluated 10 patients with histologically typical polymyositis except for an excess of muscle fibres with absent cytochrome oxidase (COX) staining. "
01/01/1997 - "Polymyositis with cytochrome oxidase negative muscle fibres. "
04/01/2013 - "Polymyositis (PM) with cytochrome C oxidase negative fibers also referred to as PM with mitochondrial pathology (PM-Mito) is characterized by the symptoms of inclusion body myositis (IBM) and by the myopathological findings of PM except for an increase of muscle fibers with insufficient mitochondrial cytochrome C oxidase activity. "
01/01/1996 - "We studied mitochondrial function in inflammatory myopathies, using cytochrome c oxidase (COX) reaction on muscle biopsy samples from 30 patients (15 with dermatomyositis, 12 with polymyositis, and 3 with inclusion body myositis) and 30 age-matched controls. "
02/12/2013 - "The ischemia group mitochondria also exhibited decreased respiration coupled to decreased expression and activity of the electron transport chain complex IV (cytochrome c oxidase). "
05/01/2007 - "We recently found that during ischemia PKA activation causes inactivation of cytochrome-c oxidase (CcO) and contributes to myocardial damage due to ischemia-reperfusion. "
04/03/2007 - "Site specific phosphorylation of cytochrome c oxidase subunits I, IVi1 and Vb in rabbit hearts subjected to ischemia/reperfusion."
06/01/2005 - "The mean rate of change in net oxidized minus reduced cytochrome a,a3 redox status in the brain following 7.5 min of ischemia was 0.49 +/- 0.26 micromol L(-1) min(-1), and, the corresponding mean magnitude of change was -1.23 +/- 0.57 micromol L(-1). "
06/01/2001 - "After 30 and 45 min of ischemia in the isolated perfused rabbit heart, subsarcolemmal mitochondria (SSM), located beneath the plasma membrane, sustain a decrease in oxidative phosphorylation through cytochrome oxidase. "
|5.||Body Weight (Weight, Body)
11/01/2011 - "Data collected included measures of training status (running volume, body weight, run-to-exhaustion time, and skeletal muscle cytochrome c oxidase activity), flow cytometric analysis of cell phenotypes and apoptosis (CD45+, CD11b+, Annexin+, Annexin+/PI+, PI+), and cytokine concentrations in cell lysates. "
08/01/2002 - "Animals were swum for 60 min.d(-1) for 1 wk. One week of swim training significantly increased plantaris cytochrome oxidase activity, as well as significantly increasing left ventricular (LV) weight and the left ventricular:body weight (LV/BW) ratio. "
06/01/1998 - "Brown adipose tissue (BAT) cytochrome oxidase activity, although slightly lower than in P rats (P = 469.96 +/- 16.20 vs CL = 414.48 +/- 11.32 U/BAT x kg body weight, P < 0.05), was still much higher than in control rats (C = 159.55 +/- 11.54 vs CL = 414.48 +/- 11.32 U/BAT x kg body weight, P < 0.05). "
10/01/1989 - "More gradual loss of organ (liver, spleen, and thymus) cytochrome c oxidase activity was observed during the next 4 wk. Body weight was equivalent between +Cu and -Cu mice, but thymus weight dropped faster in -Cu mice than +Cu mice. "
03/01/1986 - "Moreover, cold exposure also decreased body weight gain and increased brown adipose tissue mass, total cytochrome-oxidase activity, and cellularity by approximately 600-800%. "
|2.||Adenosine Triphosphate (ATP)
|5.||Glutathione (Reduced Glutathione)
|9.||Adenosine Diphosphate (ADP)
|5.||Heterologous Transplantation (Xenotransplantation)