Cyclic CMP

A cyclic nucleotide formed from CYTIDINE TRIPHOSPHATE by the action of cytidylate cyclase. It is a potential cyclic nucleotide intracellular mediator of signal transductions.

Also Known As:

Cyclic CMP, Monosodium Salt; Cytidine Cyclic 3,5 Monophosphate; Cytidine Cyclic Monophosphate; CMP, Cyclic; Cyclic Monophosphate, Cytidine; Cyclic-3',5'-Monophosphate, Cytidine; Cytidine Cyclic 3',5' Monophosphate; Monophosphate, Cytidine Cyclic; Cytidine Cyclic-3',5'-Monophosphate; Cytidine, cyclic 3',5'-(hydrogen phosphate)

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bian, Ka: 1 article (12/2014)
2.	Murad, Ferid: 1 article (12/2014)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2014 - "An understanding of the mechanisms of the translocation of the sGCβ1 subunit into the nucleus and the possible regulation of gene expression of NO and/or cyclic CMP could lead to novel and innovative approaches to cancer therapy and stem cell proliferation and differentiation. " 08/01/1981 - "High cyclic CMP levels are associated only with acute leukemia, whether myeloblastic, monoblastic, or lymphoblastic, a fact which suggests that cyclic CMP could be a biochemical marker of hematopoietic stem cell malignancy."
2.	Leukemia 08/01/1981 - "High cyclic CMP levels are associated only with acute leukemia, whether myeloblastic, monoblastic, or lymphoblastic, a fact which suggests that cyclic CMP could be a biochemical marker of hematopoietic stem cell malignancy." 08/01/1981 - "Our data show that: (a) the concentration of cyclic CMP is always lower than that of cyclic GMP or cyclic AMP; (b) in urines, the concentrations of the three nucleotides are higher in patients than in healthy volunteers, the greatest differences being observed between the cyclic CMP concentrations of acute leukemia patients and controls; and (c) in white blood cells, cyclic AMP concentration is lower in leukemic than in normal cells. " 04/25/1978 - "Demonstration, in leukemia L-1210 cells, of a phosphodiesterase acting on 3':5'-cyclic CMP but not on 3':5'-cyclic AMP or 3':5'-cyclic GMP."

Related Drugs and Biologics

1.	Cyclic GMP
2.	Cyclic AMP (AMP, Cyclic)
3.	Biomarkers (Surrogate Marker)
4.	Phosphoric Diester Hydrolases (Phosphodiesterases)
5.	Nucleotides

Related Therapies and Procedures

1.	Therapeutics