Cyproterone

An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.

Also Known As:

Networked: 80 relevant articles (8 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chen, Shih-Fen: 2 articles (12/2021 - 01/2020)
2.	Hsu, Chung-Y: 2 articles (12/2021 - 01/2020)
3.	Shen, Yu-Chih: 2 articles (12/2021 - 01/2020)
4.	Yang, Yu-Cih: 2 articles (12/2021 - 01/2020)
5.	But, Anna: 1 article (01/2022)
6.	Haukka, Jari: 1 article (01/2022)
7.	Heikinheimo, Oskari: 1 article (01/2022)
8.	Latvala, Antti: 1 article (01/2022)
9.	Partonen, Timo: 1 article (01/2022)
10.	Toffol, Elena: 1 article (01/2022)

Related Diseases

1.	Acne Vulgaris 01/01/2014 - "Despite a continuous reduction in ASI score in both the groups, according to both physician (P = 0.63) and patient (P = 0.25) assessment, cyproterone compound was not statistically more effective than conventional treatment of nodulocystic acne at the end of the study. " 07/01/2014 - "Following a European review, products containing the ethinylestradiol + cyproterone combination are back on the French market for women with acne (as second-line treatment) or hirsutism. " 07/01/2014 - "Ethinylestradiol + cyproterone: back in France for acne and hirsutism, despite frequent off-label prescription." 11/02/1985 - "At six months the acne (as assessed by overall grade) had improved by 68% in the antibiotic treated group and by 74% in the oestrogen-cyproterone treated group. " 10/15/1983 - "Cyclic cyproterone/ethinyloestradiol in acne."
2.	Prostatic Neoplasms (Prostate Cancer) 01/01/1980 - "Treatment with cyproterone seems more effective in those patients with low-stage and low-grade prostatic cancer. " 07/01/1994 - "Studies have demonstrated the effectiveness of cyproterone monotherapy in patients with prostate cancer, and for those in whom orchiectomy is not an acceptable option cyproterone may be a useful alternative. " 12/01/1973 - "[Proceedings: Value of cyproterone in the treatment of prostatic cancers with metastases]." 01/01/1980 - "[Trial of prostatic cancer treatment with estrogens associated with cyproterone]." 05/01/2003 - "Cyproterone (Schering AG) is clinically used as an antiandrogen for inoperable prostate cancer, virilizing syndromes in women, and the inhibition of sex drive in men. "
3.	Hyperandrogenism 01/01/2014 - "The efficacy of oral isotretinoin versus cyproterone compound in female patients with acne and the triad of cutaneous hyperandrogenism: A randomized clinical trial." 01/01/2014 - "This study indicates that cyproterone compound is not superior to isotretinoin in the treatment of nodulocystic acne in patient with SAHA syndrome or triad of cutaneous hyperandrogenism. " 01/01/2014 - "The aim of this study is to compare the effectiveness of isotretinoin and cyproterone compound in the treatment of nodulocystic acne, in patients with SAHA syndrome or triad of cutaneous hyperandrogenism. "
4.	Seizures (Absence Seizure) 03/01/2002 - "The aim of this study was to evaluate the efficacy of three antihormones, tamoxifen (TXF, an antiestrogen), mifepristone (MIF, an antiprogesterone) and cyproterone (CYP, an antiandrogen) in two major models of experimental epilepsy, electrically and pentetrazole (PTZ)-evoked seizures in mice. "
5.	Epilepsy (Aura) 03/01/2002 - "The aim of this study was to evaluate the efficacy of three antihormones, tamoxifen (TXF, an antiestrogen), mifepristone (MIF, an antiprogesterone) and cyproterone (CYP, an antiandrogen) in two major models of experimental epilepsy, electrically and pentetrazole (PTZ)-evoked seizures in mice. "

Related Drugs and Biologics

1.	Flutamide (Eulexin)
2.	Androgen Antagonists (Antiandrogens)
3.	Cyproterone Acetate
4.	Estradiol (Delestrogen)
5.	Estrogen Receptor Modulators (Antiestrogen)
6.	Mifepristone (RU 486)
7.	Isotretinoin (Accutane)
8.	Tetracycline (Achromycin)
9.	Tamoxifen
10.	Pentylenetetrazole (Metrazol)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Therapeutics
3.	Orchiectomy (Orchidectomy)
4.	Contraception (Birth Control)
5.	Hormone Replacement Therapy (Therapy, Hormone Replacement)