A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
Also Known As:
Networked: 30 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Das, Ashok Kumar: 1 article (04/2015)
2. Zeng, Xin: 1 article (10/2010)
3. Chen, Qian-ming: 1 article (10/2010)
4. Li, Qiong-hua: 1 article (10/2010)
5. Bartenschlager, Ralf: 1 article (08/2009)
6. Kallis, Stephanie: 1 article (08/2009)
7. Luban, Jeremy: 1 article (08/2009)
8. Lopez, Margarita Zayas: 1 article (08/2009)
9. Pertel, Thomas: 1 article (08/2009)
10. Zayas, Margarita: 1 article (08/2009)

Related Diseases

1. Neoplasms (Cancer)
2. Infection
01/01/2007 - "Although bacterial pathogens are the most common cause of infections, a wide variety of viral pathogens can also cause serious clinical manifestations mostly due to immunosupressive therapy primarily targeting cellular immunity (steroids, cyclosporins, cyclophosphamid, leflunomid, TNF-alfa antagonists etc.). "
01/01/2001 - "Biological response modifiers that show specific high-affinity interactions with Cyp, FKBPs and Hsps, including cyclosporins, FK-506 and cyclopentenone prostaglandins respectively, may block HIV-1 replication and infection, providing novel HIV-1 therapeutic strategies. "
10/01/2010 - "Reliable evidence for management of oral submucous fibrosis is still limited; amifostine, hydrolytic enzymes, ice chips and Chinese medicine may be effective in preventing oral mucositis for patients with cancer receiving radiotherapy or chemotherapy; the evidence in treating oral mucositis with allopurinol mouthwash, granulocyte macrophage-colony stimulating factor, immunoglobulin or human placentral extract for patients with cancer receiving treatment is weak and unreliable yet; there is evidence that acyclovir is efficacious in prevention and treatment of herpes simplex virus infections in patients being treated for cancer; there is strong evidence that drugs absorbed or partially absorbed from the gastrointestinal tract prevent oral candidiasis in patients receiving treatment for cancer; relapses and adverse effects are common in using beta carotene, lycopene, vitamin A or retinoids to treat oral leukoplakia; only some weak evidence is provided in using cyclosporines, retinoids, steroids or phototherapy for treating oral lichen planus; the evidence about acyclovir for treating primary herpetic gingivostomatitis is insufficient; there is little research evidence for treatment of burning mouth syndrome. "
3. Mastocytoma
4. Oral Lichen Planus
5. Herpetic Stomatitis

Related Drugs and Biologics

1. Steroids
2. beta Carotene (Betacarotene)
3. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
4. Vitamin A (Retinol)
5. Retinoids
6. Immunoglobulins (Immunoglobulin)
7. Ice
8. Amifostine (Ethyol)
9. Enzymes
10. Allopurinol (Remid)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Radiotherapy
3. Phototherapy (Light Therapy)
4. Lung Transplantation
5. Plasmapheresis