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Cyclopenthiazide
Thiazide diuretic also used as an antihypertensive agent.
Also Known As:
Cyclomethiazide; 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide
Networked:
46
relevant articles (
2
outcomes,
19
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazides: 1584
Benzothiadiazines: 3
Cyclopenthiazide: 46
Trasidrex: 5
navidrex-K: 3
Sulfones: 534
Sulfonamides: 2809
Benzothiadiazines: 3
Cyclopenthiazide: 46
Trasidrex: 5
navidrex-K: 3
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzothiadiazines: 3
Cyclopenthiazide: 46
Trasidrex: 5
navidrex-K: 3
Experts
1.
Pitchumoni, C S
: 1 article (09/2005)
2.
Trivedi, Chirag D
: 1 article (09/2005)
3.
Reyes, A J
: 1 article (03/2002)
Related Diseases
1.
Hypertension (High Blood Pressure)
02/01/1991 - "
Low-dose cyclopenthiazide in the treatment of hypertension: a one-year community-based study.
"
12/06/1962 - "
[Experiences in the treatment of hypertension with cyclopenthiazide in general practice].
"
04/01/1989 - "
In a double-blind, placebo controlled, randomised parallel study we investigated the antihypertensive activity and metabolic adverse effects of three doses of cyclopenthiazide in 53 patients with mild hypertension.
"
06/01/1981 - "
The design of the study was a double blind between patient investigation in which 9 subjects with mild hypertension received slow oxprenolol and 11 slow oxprenolol and cyclopenthiazide.
"
01/01/1977 - "
In a study of 10 patients suffering from hypertension the results showed that combination treatment with prazosin, cyclopenthiazide and a beta-blocker produced a significant fall in blood pressure.
"
2.
Cataract (Cataracts)
11/01/1988 - "
Drugs, including alcohol, that act as risk factors for cataract, and possible protection against cataract by aspirin-like analgesics and cyclopenthiazide.
"
3.
Essential Hypertension
09/01/1992 - "
Twenty-two patients with essential hypertension received a single dose of 2.5 mg cilazapril and were then randomised into a double-blind parallel group study to receive either placebo, 1.25 mg cilazapril + 0.5 mg cyclopenthiazide (CPTZ), 2.5 mg cilazapril + 0.5 mg CPTZ, or 2.5 mg cilazapril alone for 1 month.
"
07/09/1988 - "
In a double blind placebo controlled randomised parallel study the antihypertensive activity and adverse biochemical effects of three doses of cyclopenthiazide were evaluated in patients with mild essential hypertension that had been recently diagnosed or was being treated with a single drug.
"
04/01/1988 - "
Effect of low versus conventional dose cyclopenthiazide on platelet intracellular calcium in mild essential hypertension.
"
06/13/1981 - "
Oxprenolol slow-release with cyclopenthiazide KCl in the treatment of essential hypertension.
"
04/01/1988 - "
Platelet free intracellular calcium levels were measured during a double-blind, placebo-controlled parallel study to investigate the antihypertensive activity of 50 micrograms, 125 micrograms, and 500 micrograms cyclopenthiazide, in mild essential hypertension.
"
4.
Heart Failure
03/01/1988 - "
Forty-seven patients entered this comparison of frusemide-amiloride and cyclopenthiazide-potassium chloride in the treatment of congestive cardiac failure in general practice.
"
03/01/1988 - "
A comparative study of frusemide-amiloride and cyclopenthiazide-potassium chloride in the treatment of congestive cardiac failure in general practice.
"
01/01/1990 - "
An open, parallel group study comparing a frusemide/amiloride diuretic and a diuretic containing cyclopenthiazide with sustained release potassium in the treatment of congestive cardiac failure--a multicentre general practice study.
"
01/01/1990 - "
A total of 71 patients with cardiac failure requiring diuretic treatment were randomly allocated to receive either 20 mg frusemide/2.5 mg amiloride or 0.25 mg cyclopenthiazide/8.1 mmol sustained release potassium once daily for 12 weeks.
"
5.
Glucose Intolerance
03/01/1975 - "
1. A comparative cross-over trial of mefruside and cyclopenthiazide, each drug being given for 6 weeks, was conducted on thirty hypertensive patients with diabetes mellitus or impaired glucose tolerance.
"
Related Drugs and Biologics
1.
Potassium
2.
Hydrochlorothiazide (Esidrix)
3.
Amiloride (Midamor)
4.
Aspirin (Acetylsalicylic Acid)
5.
Analgesics (Analgesic Drugs)
6.
Oxprenolol (Trasicor)
7.
Antihypertensive Agents (Antihypertensives)
8.
Trasidrex
9.
Potassium Chloride
10.
navidrex-K
Related Therapies and Procedures
1.
Therapeutics